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	KU AND DNA-DEPENDENT PROTEIN KINASE (DNA-PK) DYNAMIC CONFORMATIONS AND ASSEMBLY REGULATE DNA BINDING AND THE INITIAL NONHOMOLOGOUS END JOINING COMPLEX. [My Copy] The Journal of biological chemistry (5 November 2009) by Michal Hammel, Yaping Yu, Brandi L. Mahaney, et al.Brandon Cai, Ruiqiong Ye, Barry M. Phipps, Robert P. Rambo, Greg L. Hura, Martin Pelikan, Sairei So, Ramin M. Abolfath, David J. Chen, Susan P. Lees-Miller, John A. Tainer posted to nhej ku dna-pk by qw4054 on 2009-12-01 12:34:31 as
	PIKKing on PKB: regulation of PKB activity by phosphorylation. [My Copy] Current opinion in cell biology, Vol. 21, No. 2. (April 2009), pp. 256-261. by Lana Bozulic, Brian A. Hemmings posted to pikk mtorc2 mtor dna-pk akt by guhjy on 2009-11-25 04:28:52 as
	Three-Dimensional Structure of the Human DNA-PKcs/Ku70/Ku80 Complex Assembled on DNA and Its Implications for DNA DSB Repair [My Copy] Molecular Cell, Vol. 22, No. 4. (19 May 2006), pp. 511-519. by Laura Spagnolo, Angel Rivera-Calzada, Laurence H. Pearl, Oscar Llorca posted to nhej ku em dsbs dna-pk by qw4054 on 2009-11-18 11:46:12 as
	Cryo-EM structure of the DNA-dependent protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding. [My Copy] Structure (London, England : 1993), Vol. 16, No. 3. (11 March 2008), pp. 468-477. by Dewight R. Williams, Kyung-Jong J. Lee, Jian Shi, David J. Chen, Phoebe L. Stewart posted to em dna-pk by qw4054 on 2009-11-17 20:09:06 as along with 1 person TOchi
	Cryo-EM imaging of the catalytic subunit of the DNA-dependent protein kinase [My Copy] Journal of Molecular Biology, Vol. 284, No. 4. (11 December 1998), pp. 1075-1081. by C. Chiu posted to dna-pk by qw4054 on 2009-11-17 19:58:26 as
	Synapsis of DNA ends by DNA-dependent protein kinase [My Copy] EMBO J, Vol. 21, No. 12. (17 June 2002), pp. 3192-3200. by Lisa G. DeFazio, Rachel M. Stansel, Jack D. Griffith, Gilbert Chu posted to synapsis dna-pk by qw4054 on 2009-11-12 20:28:27 as
	Defining interactions between DNA-PK and ligase IV/XRCC4 [My Copy] DNA Repair, Vol. 1, No. 3. (28 March 2002), pp. 225-235. by H. Hsu posted to xrcc4 nhej dsbs dnaligase dna-pk by qw4054 on 2009-11-12 19:12:42 as
	DNA-dependent Protein Kinase and XRCC4-DNA Ligase IV Mobilization in the Cell in Response to DNA Double Strand Breaks [My Copy] Journal of Biological Chemistry, Vol. 280, No. 8. (25 February 2005), pp. 7060-7069. by JÃ©rÃ´me Drouet, Christine Delteil, Jacques LefranÃ§ois, Patrick Concannon, Bernard Salles, Patrick Calsou posted to xrcc4 dsbs dnaligase dna-pk by qw4054 on 2009-11-12 18:23:07 as
	The leucine rich region of DNA-PKcs contributes to its innate DNA affinity. [My Copy] Nucleic acids research, Vol. 33, No. 22. (2005), pp. 6972-6981. by Shikha Gupta, Katheryn Meek posted to dna-pk dna by qw4054 on 2009-11-12 18:16:43 as
	Terminal DNA structure and ATP influence binding parameters of the DNA-dependent protein kinase at an early step prior to DNA synapsis. [My Copy] Nucleic acids research, Vol. 34, No. 4. (2006), pp. 1112-1120. by Marko Jovanovic, William S. Dynan posted to synapsis end dna-pk by qw4054 on 2009-11-12 18:14:41 as
	Structural model of full-length human Ku70-Ku80 heterodimer and its recognition of DNA and DNA-PKcs. [My Copy] EMBO reports, Vol. 8, No. 1. (08 January 2007), pp. 56-62. by Angel Rivera-Calzada, Laura Spagnolo, Laurence H. Pearl, Oscar Llorca posted to ku dna-pk dna by qw4054 on 2009-11-12 18:04:39 as
	The DNA repair complex DNA-PK, a pharmacological target in cancer chemotherapy and radiotherapy [My Copy] Pathologie Biologie, Vol. 54, No. 4. (May 2006), pp. 185-193. by B. Salles, P. Calsou, P. Frit, C. Muller posted to nhej dna-pk by qw4054 on 2009-11-11 15:47:10 as along with 1 person guhjy
	The DNA-dependent protein kinase: the director at the end [My Copy] Immunological Reviews, Vol. 200, No. 1. (August 2004), pp. 132-141. by Katheryn Meek, Shikha Gupta, Dale A. Ramsden, Susan P. Lees-Miller posted to dna-pk by qw4054 on 2009-10-22 14:32:00 as along with 2 people ecattell TOchi
	DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks [My Copy] DNA Repair, Vol. 7, No. 10. (01 October 2008), pp. 1680-1692. by Y. Yu, B. Mahaney, K. Yano, et al.R. Ye, S. Fang, P. Douglas, D. Chen, S. Leesmiller posted to xlf dna-pk atm by qw4054 on 2009-08-17 17:49:21 as
	DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys? [My Copy] The Journal of cell biology, Vol. 179, No. 2. (22 October 2007), pp. 183-186. by Eric Weterings, David J. Chen posted to damage dna dna-pk repair by mkiyer to the group Chinnaiyan Lab on 2009-08-04 03:44:02 as
	Regulation of p53: the next generation. [My Copy] Cell cycle (Georgetown, Tex.), Vol. 7, No. 20. (October 2008), pp. 3149-3153. by C. Blattner posted to dna-damage dna-pk p53 by guhjy on 2009-02-09 14:22:25 as
	PIKK-ing a New Partner: A New Role for PKB in the DNA Damage Response [My Copy] Cancer Cell, Vol. 13, No. 5. (06 May 2008), pp. 379-380. by S. Leesmiller posted to akt dna-damage dna-pk by guhjy on 2009-02-08 00:59:36 as
	Ku80 deletion suppresses spontaneous tumors and induces a p53-mediated DNA damage response. [My Copy] Cancer research, Vol. 68, No. 22. (15 November 2008), pp. 9497-9502. by V. B. Holcomb, F. Rodier, Y. Choi, et al.R. A. Busuttil, H. Vogel, J. Vijg, J. Campisi, P. Hasty posted to cancer dna-damage dna-pk ko p53 by guhjy on 2009-02-08 00:30:48 as
	DNA-PK suppresses a p53-independent apoptotic response to DNA damage [My Copy] EMBO Reports, Vol. aop, No. current. (05 December 2008) by Kay E. Gurley, Russell Moser, Yansong Gu, Paul Hasty, Christopher J. Kemp posted to apoptosis dna-damage dna-pk p53 by guhjy on 2009-02-07 16:24:52 as
	Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage [My Copy] Nature, Vol. aop, No. current. (02 March 2005) by Jacob Falck, Julia Coates, Stephen P. Jackson posted to atm dna-damage dna-pk by guhjy on 2009-01-31 10:08:52 as along with 1 person DNAReplication
	DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases. [My Copy] Journal of molecular biology, Vol. 385, No. 3. (23 January 2009), pp. 800-810. by H. Yajima, K. J. Lee, S. Zhang, J. Kobayashi, B. P. Chen posted to atm dna-damage dna-pk by guhjy on 2009-01-29 10:17:31 as
	In vivo analysis of protein kinase B (PKB)/Akt regulation in DNA-PKcs-null mice reveals a role for PKB/Akt in DNA damage response and tumorigenesis. [My Copy] The Journal of biological chemistry, Vol. 283, No. 44. (31 October 2008), pp. 30025-30033. by B. Surucu, L. Bozulic, D. Hynx, A. Parcellier, B. A. Hemmings posted to akt cancer dna-damage dna-pk by guhjy on 2009-01-28 15:47:06 as
	KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation [My Copy] Cellular Signalling, Vol. 20, No. 11. (November 2008), pp. 1978-1985. by Takuya Abe, Masamichi Ishiai, Yoshifumi Hosono, et al.Akari Yoshimura, Shusuke Tada, Noritaka Adachi, Hideki Koyama, Minoru Takata, Shunichi Takeda, Takemi Enomoto posted to apoptosis dna-damage dna-pk by guhjy on 2008-11-16 08:43:53 as along with 2 people qw4054 TOchi
	Ku entry into DNA inhibits inward DNA transactions in vitro. [My Copy] The Journal of biological chemistry, Vol. 275, No. 46. (17 November 2000), pp. 35684-35691. by P. Frit, R. Y. Li, D. Arzel, B. Salles, P. Calsou posted to dna-pk ku nhej repair by ramalldf on 2008-11-01 21:38:13 as
	DNA looping by Ku and the DNA-dependent protein kinase. [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, No. 9. (29 April 1997), pp. 4267-4272. by R. B. Cary, S. R. Peterson, J. Wang, D. G. Bear, E. M. Bradbury, D. J. Chen posted to afm dna-pk ku nhej single-molecule by ramalldf on 2008-11-01 21:34:41 as along with 1 person TOchi
	Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks. [My Copy] Current opinion in genetics & development, Vol. 7, No. 1. (February 1997), pp. 99-104. by M. R. Lieber, U. Grawunder, X. Wu, M. Yaneva posted to dna-pk ku nhej by ramalldf on 2008-11-01 21:33:25 as
	The role of DNA dependent protein kinase in synapsis of DNA ends. [My Copy] Nucleic acids research, Vol. 31, No. 24. (15 December 2003), pp. 7238-7246. by E. Weterings, N. S. Verkaik, H. T. Brüggenwirth, J. H. Hoeijmakers, D. C. van Gent posted to dna-pk ku nhej repair by ramalldf on 2008-11-01 21:32:05 as
	Ataxia Telangiectasia Mutated (ATM) Is Essential for DNA-PKcs Phosphorylations at the Thr-2609 Cluster upon DNA Double Strand Break [My Copy] J. Biol. Chem., Vol. 282, No. 9. (2 March 2007), pp. 6582-6587. by Benjamin P. Chen, Naoya Uematsu, Junya Kobayashi, et al.Yaniv Lerenthal, Andrea Krempler, Hirohiko Yajima, Markus Lobrich, Yosef Shiloh, David J. Chen posted to atm dna-damage dna-pk by guhjy on 2008-10-27 14:30:16 as along with 1 person fredrikberglund
	Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks. [My Copy] The Journal of biological chemistry, Vol. 282, No. 14. (6 April 2007), pp. 10138-10145. by N. Tomimatsu, C. G. Tahimic, A. Otsuki, et al.S. Burma, A. Fukuhara, K. Sato, G. Shiota, M. Oshimura, D. J. Chen, A. Kurimasa posted to atm dna-damage dna-pk by guhjy on 2008-10-25 03:30:02 as
	Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441. [My Copy] Cancer research, Vol. 66, No. 10. (15 May 2006), pp. 5354-5362. by Y. Zhao, H. D. Thomas, M. A. Batey, et al.I. G. Cowell, C. J. Richardson, R. J. Griffin, A. H. Calvert, D. R. Newell, G. C. Smith, N. J. Curtin posted to cancer dna-pk inhibitor by guhjy on 2008-10-23 17:07:24 as along with 1 person fredrikberglund
	The life and death of DNA-PK [My Copy] Oncogene, Vol. aop, No. current. (13 December 2004) by Spencer J. Collis, Theodore L. Deweese, Penelope A. Jeggo, Antony R. Parker posted to dna-pk by guhjy on 2008-08-31 11:20:29 as along with 1 person ecattell
	Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair. [My Copy] Molecular cancer therapeutics, Vol. 7, No. 7. (July 2008), pp. 1772-1781. by M. Toulany, R. Kehlbach, U. Florczak, et al.A. Sak, S. Wang, J. Chen, M. Lobrich, H. P. Rodemann posted to akt dna-pk by guhjy on 2008-08-31 10:51:58 as
	DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells. [My Copy] Cancer research, Vol. 68, No. 1. (1 January 2008), pp. 89-97. by S. J. Arlander, B. T. Greene, C. L. Innes, R. S. Paules posted to atm dna-pk by guhjy on 2008-08-31 09:21:43 as
	Modulation of cellular response to anticancer treatment by caffeine: inhibition of cell cycle checkpoints, DNA repair and more. [My Copy] Current pharmaceutical biotechnology, Vol. 9, No. 4. (August 2008), pp. 325-336. by Michal Sabisz, Andrzej Skladanowski posted to atm cancer coffee dna-pk by guhjy on 2008-08-24 06:32:48 as along with 2 people bertelsen Zephyrus
	Akt signaling: a damaging interaction makes good. [My Copy] Trends in biochemical sciences, Vol. 33, No. 8. (August 2008), pp. 356-359. by A. Toker posted to dna-damage dna-pk akt by guhjy on 2008-08-24 05:50:03 as
	PKB[alpha]/Akt1 Acts Downstream of DNA-PK in the DNA Double-Strand Break Response and Promotes Survival [My Copy] Molecular Cell, Vol. 30, No. 2. (25 April 2008), pp. 203-213. by Lana Bozulic, Banu Surucu, Debby Hynx, Brian A. Hemmings posted to akt dna-damage dna-pk p21 pi3k by guhjy on 2008-08-24 05:08:29 as along with 1 person zhlei
	p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK. [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, No. 22. (3 June 2008), pp. 7785-7790. by K. A. Boehme, R. Kulikov, C. Blattner posted to dna-damage dna-pk p53 pi3k akt by guhjy on 2008-08-24 05:04:24 as
	A mechanism for DNA-PK activation requiring unique contributions from each strand of a DNA terminus and implications for microhomology-mediated nonhomologous DNA end joining [My Copy] Nucl. Acids Res., Vol. 36, No. 12. (1 July 2008), pp. 4022-4031. by Katherine S. Pawelczak, John J. Turchi posted to dna-pk dna-pkcs ku by TOchi on 2008-07-10 16:03:25 as
	Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. [My Copy] J Cell Biol, Vol. 173, No. 2. (24 April 2006), pp. 195-206. by S. Bekker-Jensen, C. Lukas, R. Kitagawa, et al.F. Melander, M. B. Kastan, J. Bartek, J. Lukas posted to atm atr dna-damage dna-pk by zhlei on 2008-04-29 17:59:25 as along with 2 people cannin DNAReplication
	Coordinate 5' and 3' endonucleolytic trimming of terminally blocked blunt DNA double-strand break ends by Artemis nuclease and DNA-dependent protein kinase [My Copy] Nucl. Acids Res. (25 April 2008), gkn205. by Steven M. Yannone, Imran S. Khan, Rui-Zhe Zhou, Tong Zhou, Kristoffer Valerie, Lawrence F. Povirk posted to artemis dna-pk nhej by TOchi on 2008-04-26 15:39:16 as
	Activation of the DNA-dependent Protein Kinase Stimulates Nuclear Export of the Androgen Receptor in Vitro [My Copy] J. Biol. Chem., Vol. 283, No. 16. (18 April 2008), pp. 10568-10580. by Leonard C. Shank, Joshua B. Kelley, Daniel Gioeli, et al.Chun-Song Yang, Adam Spencer, Lizabeth A. Allison, Bryce M. Paschal posted to dna-pk by TOchi on 2008-04-21 13:04:55 as
	Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development [My Copy] PNAS, Vol. 98, No. 6. (13 March 2001), pp. 3243-3248. by Joann Sekiguchi, David O. Ferguson, Hua T. Chen, et al.Eva M. Yang, John Earle, Karen Frank, Scott Whitlow, Yansong Gu, Yang Xu, Andre Nussenzweig, Frederick W. Alt posted to atm dna-pk ku70-80 synthetic-lethal by DNAReplication on 2007-08-21 16:32:13 as
	Synthetic lethality between mutation in Atm and DNA-PKcs during murine embryogenesis [My Copy] Current Biology, Vol. 11, No. 3. (6 February 2001), pp. 191-194. by Kay E. Gurley, Christopher J. Kemp posted to atm dna-pk knockout-mouse radiation-sensitivity synthetic-lethal by DNAReplication on 2007-08-21 16:18:24 as
	DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus [My Copy] Nat Genet, Vol. 17, No. 4. (December 1997), pp. 483-486. by Chamelli Jhappan, Herbert C. Morse, Robert D. Fleischmann, Michael M. Gottesman, Glenn Merlino posted to dna-pk knockout-mouse vdj-recombination by DNAReplication on 2007-08-11 18:43:04 as

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