Tag drugdiscovery [102 articles] Export

Recent papers classified by the tag drugdiscovery.

	STITCH 2: an interaction network database for small molecules and proteins [My Copy] Nucl. Acids Res. (6 November 2009), gkp937. by Michael Kuhn, Damian Szklarczyk, Andrea Franceschini, et al.Monica Campillos, Christian von Mering, Lars J. Jensen, Andreas Beyer, Peer Bork posted to ressource drugdiscovery database bioinformatics by Yanno on 2009-11-10 09:37:20 as along with 2 people guhjy neils
	Predicting new molecular targets for known drugs [My Copy] Nature In Nature, Vol. 462, No. 7270. (01 November 2009), pp. 175-181. by Michael J. Keiser, Vincent Setola, John J. Irwin, et al.Christian Laggner, Atheir I. Abbas, Sandra J. Hufeisen, Niels H. Jensen, Michael B. Kuijer, Roberto C. Matos, Thuy B. Tran, Ryan Whaley, Richard A. Glennon, Jerome Hert, Kelan L. H. Thomas, Douglas D. Edwards, Brian K. Shoichet, Bryan L. Roth posted to target drugdiscovery datamining chemoinformatics by Yanno on 2009-11-09 09:45:54 as along with 15 people and 1 group flbarroso venancio okapi ahmetbakan zufar pablocarb zwang TRHvidsten phoenixzxl qshao mnishimu tmmurali sjcockell seb1 abhishek_tiwari Journal picks
	Drug Discovery and Natural Products: End of an Era or an Endless Frontier? [My Copy] Science, Vol. 325, No. 5937. (10 July 2009), pp. 161-165. by Jesse W. H. Li, John C. Vederas posted to review naturalproducts drugdiscovery by Yanno on 2009-11-06 13:58:15 as along with 6 people chemnerd1 guhjy richardbickerton reyez TRHvidsten flbarroso
	Influence of Protonation, Tautomeric, and Stereoisomeric States on Protein−Ligand Docking Results [My Copy] Journal of Chemical Information and Modeling, Vol. 0, No. 0. (0000) by Ten, Thomas E. Exner posted to glide drugdiscovery docking charge by snichols15 on 2009-10-21 23:52:13 as along with 1 person ima
	Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening. [My Copy] J Med Chem, Vol. 47, No. 7. (25 March 2004), pp. 1750-1759. by T. A. Halgren, R. B. Murphy, R. A. Friesner, et al.H. S. Beard, L. L. Frye, W. T. Pollard, J. L. Banks posted to rafriesner glide drugdiscovery docking by snichols15 on 2009-10-19 01:26:55 as along with 4 people flbarroso BragilMassoud schlauchi LamBras
	The Many Roles of Computation in Drug Discovery [My Copy] Science, Vol. 303, No. 5665. (19 March 2004), pp. 1813-1818. by William L. Jorgensen posted to wljorgensen hiv drugdiscovery compchem by snichols15 on 2009-10-19 01:21:59 as along with 8 people dgruiz kuhn balicea blackbart ramensky euan onufriev ashaytan
	A Mapping of Drug Space from the Viewpoint of Small Molecule Metabolism [My Copy] PLoS Comput Biol, Vol. 5, No. 8. (21 August 2009), e1000474. by James C. Adams, Michael J. Keiser, Li Basuino, et al.Henry F. Chambers, Deok-Sun Lee, Olaf G. Wiest, Patricia C. Babbitt posted to pathways metabolic drugdiscovery by thomaskelder on 2009-08-21 18:58:10 as along with 8 people and 1 group sobolevnrm nickolay klexa bdessailly pablocarb ptrobajo biomcgary reyez Orengo Group Journal Picks
	Novel anticancer targets: revisiting ERBB2 and discovering ERBB3 [My Copy] Nat Rev Cancer, Vol. 9, No. 7. (18 July 2009), pp. 463-475. by Jose Baselga, Sandra M. Swain posted to cancer drugdiscovery erbb kinase kinaseinhibition review by sschurer on 2009-07-14 18:20:35 as along with 2 people misonneh renatomilani
	Cell cycle kinases as therapeutic targets for cancer [My Copy] Nat Rev Drug Discov, Vol. 8, No. 7. (01 July 2009), pp. 547-566. by Silvia Lapenna, Antonio Giordano posted to cancer cdk drugdiscovery kinase kinaseinhibition review by sschurer on 2009-07-14 18:16:07 as along with 3 people kokphinchooi guhjy reyez
	Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds. [My Copy] Nature reviews. Drug discovery, Vol. 8, No. 7. (July 2009), pp. 567-578. by Yan Feng, Timothy J. Mitchison, Andreas Bender, Daniel W. Young, John A. Tallarico posted to drugdiscovery integration phenotypicprofiling review targetfishing by sschurer on 2009-07-13 17:59:07 as along with 4 people abhishek_tiwari guhjy sameersoi mingzhi
	Transforming fragments into candidates: small becomes big in medicinal chemistry [My Copy] Drug Discovery Today, Vol. 14, No. 13-14. (31 July 2009), pp. 630-646. by Gerdien E. de Kloe, David Bailey, Rob Leurs, Iwan J. P. de Esch posted to drugdiscovery fragmentbaseddesign leadcompounds library ligandefficiency review by sschurer on 2009-06-30 14:33:27 as along with 1 person and 1 group pslee Fragment Based Drug Discovery
	Methodological approaches in application of synthetic lethality screening towards anticancer therapy [My Copy] British Journal of Cancer, Vol. aop, No. current. (24 March 2009) by D. Canaani posted to cancer drugdiscovery review rnai screen syntheticlethal by myzhang on 2009-06-22 19:28:52 as
	Kinase-targeted libraries: the design and synthesis of novel, potent, and selective kinase inhibitors. [My Copy] Drug discovery today, Vol. 14, No. 5-6. (21 March 2009), pp. 291-297. by Irini Akritopoulou-Zanze, Philip J. Hajduk posted to chemical chemogenomics drugdiscovery kinase library by Yanno on 2009-06-04 17:11:37 as along with 3 people guhjy sschurer pslee
	Off-Target Decoding of a Multitarget Kinase Inhibitor by Chemical Proteomics [My Copy] ChemBioChem, Vol. 9999, No. 9999. (2009), NA. by Enrico Missner, Inke Bahr, Volker Badock, Ulrich Lücking, Gerhard Siemeister, Peter Donner posted to chemogenomics drugdiscovery kinase screening by Yanno on 2009-06-04 16:14:08 as along with 1 person anwazo
	Where is the hope for drug discovery? Let history tell the future. [My Copy] Drug discovery today (4 August 2008) by De-Xin X. Kong, Xue-Juan J. Li, Hong-Yu Y. Zhang posted to drugdiscovery perspective by Yanno on 2009-04-30 11:02:06 as along with 2 people flbarroso tbinbal
	A network view of disease and compound screening. [My Copy] Nature reviews. Drug discovery, Vol. 8, No. 4. (April 2009), pp. 286-295. by Eric E. Schadt, Stephen H. Friend, David A. Shaywitz posted to deseasenetwork drugdiscovery net network polypharmacology review by sschurer on 2009-04-02 20:40:06 as along with 11 people jbesnard abhishek_tiwari pablocarb richardbickerton sameersoi mingzhi oelemento ptrobajo phoenixzxl reyez guhjy
	Efficient Drug Lead Discovery and Optimization [My Copy] Accounts of Chemical Research, Vol. 0, No. 0. (0000) by William L. Jorgensen posted to docking drugdiscovery leadcompounds review structurebaseddesign by sschurer on 2009-03-31 23:44:20 as along with 6 people and 2 groups nanonan tbinbal Thermaneutist jmccammon superpyrin sobolevnrm McCammon baker-group
	Ligand efficiency and fragment-based drug discovery. [My Copy] Drug discovery today, Vol. 14, No. 5-6. (30 March 2009), pp. 278-283. by Scott D. Bembenek, Brett A. Tounge, Charles H. Reynolds posted to drugdiscovery fragmentbaseddesign ligandefficiency review by sschurer on 2009-03-12 17:49:38 as along with 3 people higueruelo jerome pslee
	G-protein-coupled receptor-focused drug discovery using a target class platform approach. [My Copy] Drug discovery today, Vol. 14, No. 5-6. (30 March 2009), pp. 231-240. by Ralf Heilker, Michael Wolff, Christofer S. Tautermann, Michael Bieler posted to drugdiscovery gpcr review by sschurer on 2009-03-12 17:41:17 as along with 1 person guhjy
	De Novo Drug Design Using Multiobjective Evolutionary Graphs [My Copy] Journal of Chemical Information and Modeling, Vol. 0, No. 0. (0000) by Christos A. Nicolaou, Joannis Apostolakis, Costas S. Pattichis posted to denovodesign drugdiscovery geneticalgorithm graphsearch multiobjective optimization pareto by sschurer on 2009-03-04 17:18:04 as along with 2 people and 1 group carlosjavierna oteri Structural Biology Group TorVergata
	Genetic programming for human oral bioavailability of drugs [My Copy] In GECCO '06: Proceedings of the 8th annual conference on Genetic and evolutionary computation (2006), pp. 255-262. by Francesco Archetti, Stefano Lanzeni, Enza Messina, Leonardo Vanneschi posted to drugdiscovery masterthesis by scarcelan on 2009-02-26 03:12:20 as
	Gaining Insight into Off-Target Mediated Effects of Drug Candidates with a Comprehensive Systems Chemical Biology Analysis [My Copy] Journal of Chemical Information and Modeling, Vol. 0, No. 0. (0000) by Josef Scheiber, Bin Chen, Mariusz Milik, et al.Sai C. Sukuru, Andreas Bender, Dmitri Mikhailov, Steven Whitebread, Jacques Hamon, Kamal Azzaoui, Laszlo Urban, Meir Glick, John W. Davies, Jeremy L. Jenkins posted to adversedrugreactions chemicalbiology drugdiscovery by sschurer on 2009-02-24 18:02:01 as along with 4 people zimbo1 jerome jbesnard reyez
	Translational Toxicology and the Work of the Predictive Safety Testing Consortium [My Copy] Clin Pharmacol Ther, Vol. 85, No. 3. (21 January 2009), pp. 327-330. by W. B. Mattes, E. G. Walker posted to drugdiscovery drugsafety review toxicology by sschurer on 2009-02-19 14:52:46 as
	A class of selective antibacterials derived from a protein kinase inhibitor pharmacophore [My Copy] Proceedings of the National Academy of Sciences, Vol. 106, No. 6. (10 February 2009), pp. 1737-1742. by Richard J. Miller, Steve Dunham, Igor Mochalkin, et al.Craig Banotai, Matthew Bowman, Susan Buist, Bill Dunkle, Debra Hanna, James H. Harwood, Michael D. Huband, Alla Karnovsky, Michael Kuhn, Chris Limberakis, Jia Y. Liu, Shawn Mehrens, Thomas W. Mueller, Lakshmi Narasimhan, Adam Ogden, Jeff Ohren, Vara J. V. N. Prasad, John A. Shelly, Laura Skerlos, Mark Sulavik, Hayden V. Thomas, Steve Vanderroest, Liann Wang, Zhigang Wang, Amy Whitton, Tong Zhu, Kendall C. Stover posted to bacterial drugdiscovery kinase kinaseinhibition xraystructure by sschurer on 2009-02-12 16:08:11 as
	Knocking down barriers: advances in siRNA delivery [My Copy] Nat Rev Drug Discov, Vol. 8, No. 2. (01 February 2009), pp. 129-138. by Kathryn A. Whitehead, Robert Langer, Daniel G. Anderson posted to drugdiscovery rnainterference by sschurer on 2009-02-06 16:46:54 as along with 2 people qshao guhjy
	Deal watch: Bristol-Myers Squibb and Exelixis collaborate on kinase inhibitors [My Copy] Nat Rev Drug Discov, Vol. 8, No. 2. (February 2009), pp. 98-99. posted to drugdiscovery kinase kinaseinhibition by sschurer on 2009-02-06 16:44:11 as
	The promises and pitfalls of RNA-interference-based therapeutics [My Copy] Nature, Vol. 457, No. 7228. (21 January 2009), pp. 426-433. by Daniela Castanotto, John J. Rossi posted to drugdiscovery review rnainterference by sschurer on 2009-02-06 16:07:52 as along with 2 people jfr ealloza
	Structure-based maximal affinity model predicts small-molecule druggability [My Copy] Nat Biotech, Vol. 25, No. 1. (08 January 2007), pp. 71-75. by Alan C. Cheng, Ryan G. Coleman, Kathleen T. Smyth, et al.Qing Cao, Patricia Soulard, Daniel R. Caffrey, Anna C. Salzberg, Enoch S. Huang posted to bindingsites drugdiscovery drugtargets proteinligandinteraction by sschurer on 2009-02-05 01:28:25 as along with 9 people mingzhi flbarroso phoenixzxl ubcg08l ucbcjbm jerome yeastyboy willpitt higueruelo
	Principles for 3D/4D QSAR classification of drugs [My Copy] Drug Discovery Today (07 September 2008) by V. Potemkin, M. Grishina posted to 3d4d biologicalsubstratesearch bis classification drugclassification drugdiscovery drugs qsar qsarselfconsistentfield by didacmargaix on 2009-01-21 04:17:36 as along with 3 people sg45653 sschurer zimbo1
	‘Metabolite-likeness’ as a criterion in the design and selection of pharmaceutical drug libraries [My Copy] Drug Discovery Today, Vol. 14, No. 1-2. (28 January 2009), pp. 31-40. by P. Dobson, Y. Patel, D. Kell posted to drugdiscovery druglike metabolite by sschurer on 2009-01-07 17:24:18 as along with 9 people mingzhi richardbickerton massivemayhem vpenelle jmuhlich lptolik pauldobson egonw dullhunk
	Target-specific anti-fungal discovery by targeting Geotrichum candidum histidinol dehydrogenase: a hybrid approach. [My Copy] Chemical biology & drug design, Vol. 72, No. 3. (September 2008), pp. 229-234. by S. Pahwa, A. G. Chavan, R. Jain, N. Roy posted to drugdiscovery by nilanjanroy on 2008-11-01 02:29:34 as
	New G-protein-coupled receptor crystal structures: insights and limitations. [My Copy] Trends in pharmacological sciences, Vol. 29, No. 2. (February 2008), pp. 79-83. by B. Kobilka, G. F. Schertler posted to drugdiscovery gpcr structurebaseddesign by sschurer on 2008-10-24 17:50:40 as along with 2 people ubcg08l IrinaMoreira
	A network solution [My Copy] Nature, Vol. 455, No. 7214. (October 2008), pp. 730-731. by Adriano Henney, Giulio Superti-Furga posted to drugdiscovery opinion systemsbiology by Yanno on 2008-10-16 16:01:43 as along with 4 people raiyar reyez alexknight dullhunk
	Hydra: A Self Regenerating High Performance Computing Grid for Drug Discovery [My Copy] J. Chem. Inf. Model. (14 March 2008) by Drew Bullard, Alberto Gobbi, Matthew A. Lardy, Charles Perkins, Zach Little posted to drugdiscovery grid hpc mscproject by ibuch on 2008-09-25 11:45:00 as along with 2 people mrt2k9 middledomain
	Design of a grid service-based platform for in silico protein-ligand screenings. [My Copy] Computer methods and programs in biomedicine (2 September 2008) by Marshall J J. Levesque, Kohei Ichikawa, Susumu Date, Jason H H. Haga posted to drugdiscovery grid md mscproject proteinligand by ibuch on 2008-09-25 11:03:24 as
	Hunting for predictive computational drug-discovery models [My Copy] Expert Review of Anti-Infective Therapy, Vol. 6, No. 3. (June 2008), pp. 291-293. by Snow, D. Christopher posted to bioinformatics drugdiscovery review by Yanno on 2008-09-09 12:51:05 as
	Systems biology in drug discovery. [My Copy] Nature biotechnology, Vol. 22, No. 10. (October 2004), pp. 1253-1259. by E. C. Butcher, E. L. Berg, E. J. Kunkel posted to drugdiscovery review systemsbiology by Yanno on 2008-09-09 12:27:41 as along with 9 people and 4 groups flbarroso ubcg08l dlobo rhem1224 tny karthikram mingzhi maburkitt kengg GEB TCR_Signaling Neoscientists SysbioMPI-TCells
	Picomolar Inhibitors as Transition-State Probes of 5′-Methylthioadenosine Nucleosidases [My Copy] ACS Chem. Biol., Vol. 2, No. 11. (20 November 2007), pp. 725-734. by Jemy A. Gutierrez, Minkui Luo, Vipender Singh, et al.Lei Li, Rosemary L. Brown, Gillian Norris, E., Gary B. Evans, Richard H. Furneaux, Peter C. Tyler, Gavin F. Painter, Dirk H. Lenz, Vern L. Schramm posted to drugdiscovery transitionstate by gemmalholliday on 2008-08-07 11:58:48 as
	PDTD: a web-accessible protein database for drug target identification [My Copy] BMC Bioinformatics, Vol. 9 (19 February 2008), 104. by Zhenting Gao, Honglin Li, Hailei Zhang, et al.Xiaofeng Liu, Ling Kang, Xiaomin Luo, Weiliang Zhu, Kaixian Chen, Xicheng Wang, Hualiang Jiang posted to drugdiscovery by gemmalholliday on 2008-08-07 11:31:47 as along with 3 people flbarroso guhjy ajaymalik
	How many drug targets are there? [My Copy] Nature Reviews Drug Discovery, Vol. 5, No. 12., pp. 993-996. by John P. Overington, Bissan Al-Lazikani, Andrew L. Hopkins posted to drugdiscovery by gemmalholliday on 2008-08-07 11:17:53 as along with 10 people and 1 group BragilMassoud cannin kuhn bicko mingzhi higueruelo srp33 ramensky aheilbut ajaymalik libr
	Rational design of transition-state analogues as potent enzyme inhibitors with therapeutic applications. [My Copy] ACS chemical biology, Vol. 2, No. 11. (20 November 2007), pp. 711-714. by T. L. Amyes, J. P. Richard posted to drugdiscovery transitionstate by gemmalholliday on 2008-08-07 11:00:32 as along with 1 person apostola
	Systems biology, metabolic modelling and metabolomics in drug discovery and development. [My Copy] Drug discovery today, Vol. 11, No. 23-24. (December 2006), pp. 1085-1092. by Douglas B. Kell posted to drugdiscovery by gemmalholliday on 2008-08-07 10:55:58 as along with 14 people and 2 groups dadiamah peterli flbarroso schwartzjmc egonw irenas nicklynch alexg dullhunk mhucka raiyar fishtank shikin alanrw steinmetzlab GeneGo
	From toxicological problem to therapeutic use: the discovery of the mode of action of 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC), its toxicology and development as a drug. [My Copy] Journal of inherited metabolic disease, Vol. 21, No. 5. (August 1998), pp. 498-506. by E. A. Lock, M. K. Ellis, P. Gaskin, et al.M. Robinson, T. R. Auton, W. M. Provan, L. L. Smith, M. P. Prisbylla, L. C. Mutter, D. L. Lee posted to drugdiscovery by gemmalholliday on 2008-08-07 10:55:33 as
	The use of metabolomics for the discovery of new biomarkers of effect. [My Copy] Toxicol Lett (25 May 2007) by B van Ravenzwaay, G Coelho-Palermo C. Cunha, E Leibold, et al.R Looser, W Mellert, A Prokoudine, T Walk, J Wiemer posted to drugdiscovery by gemmalholliday on 2008-08-07 10:54:15 as along with 1 person guhjy
	Structure-and-mechanism-based design and discovery of therapeutics for cocaine overdose and addiction. [My Copy] Org Biomol Chem, Vol. 6, No. 5. (7 March 2008), pp. 836-843. by F. Zheng, C. G. Zhan posted to drugdiscovery by gemmalholliday on 2008-08-07 10:53:40 as along with 2 people schmoutz ucbcjbm
	Enzyme inhibitors as chemical tools to study enzyme catalysis: rational design, synthesis, and applications. [My Copy] Chemical record (New York, N.Y.), Vol. 5, No. 4. (2005), pp. 209-228. by J. Hiratake posted to drugdiscovery by gemmalholliday on 2008-08-07 10:51:04 as
	Enzymes as a special class of therapeutic target: clinical drugs and modes of action. [My Copy] Current opinion in structural biology, Vol. 17, No. 6. (December 2007), pp. 674-679. by J. G. Robertson posted to drugdiscovery by gemmalholliday on 2008-08-07 10:46:51 as
	Mechanistic basis of enzyme-targeted drugs. [My Copy] Biochemistry, Vol. 44, No. 15. (19 April 2005), pp. 5561-5571. by J. G. Robertson posted to drugdiscovery by gemmalholliday on 2008-08-07 10:41:51 as along with 1 person and 1 group caporaso biomedical-nlp
	In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling [My Copy] Br J Pharmacol, Vol. 152, No. 1. (4 June 2007), pp. 9-20. by S. Ekins, J. Mestres, B. Testa posted to drugdiscovery methods msc by ibuch on 2008-07-25 14:22:57 as
	In silico pharmacology for drug discovery: applications to targets and beyond [My Copy] Br J Pharmacol, Vol. 152, No. 1. (4 June 2007), pp. 21-37. by S. Ekins, J. Mestres, B. Testa posted to drugdiscovery mscproject by ibuch on 2008-07-25 14:21:44 as along with 2 people and 2 groups nicholasflann jmrivort G-quadruplex Supramolecular

Note: You may cite this page as: http://www.citeulike.org/tag/drugdiscovery

Result page: 1 2 3 Next

review	33
kinase	19
drug	12
kinaseinhibition	12
systemsbiology	9
datamining	7
cancer	6
chemical	6
library	6
method	5
networks	5
chemogenomics	4
docking	4
gpcr	4
inhibitor	4
screening	4
statistics	4
activity_profile	3
assay	3
bacterial	3
bioinformatics	3
fragmentbaseddesign	3
hcs	3
leadcompounds	3
methods	3
mscproject	3
pathways	3
prediction	3
seh	3
side_effects	3
similarity	3
adversedrugreactions	2
biologicalsubstratesearch	2
bis	2
chemoinformatics	2
denovodesign	2
descriptors	2
drugclassification	2
glide	2
grid	2
hts	2
ligandefficiency	2
medicinalchemistry	2
naturalproducts	2
opinion	2
proteinligandinteraction	2
proteomics	2
qsarselfconsistentfield	2
rnainterference	2
serotonin	2
structurebaseddesign	2
target	2
targetfishing	2
transitionstate	2
tuberculosis	2
addiction	1
adrenergic	1
cdk	1
cellbased	1
charge	1
cocain	1
deseasenetwork	1
disease	1
drugdesign	1
druglike	1
drugtargets	1
flowcytometry	1
function	1
genomics	1
hat	1
highthrouhput	1
histoneacetyltransferases	1
history	1
hiv	1
integration	1
interaction	1
kinasesar	1
kinome	1
masterthesis	1
md	1
metabolite	1
modeofaction	1
multiobjective	1
network	1
nrd	1
phenotype	1
phenotypicprofiling	1
phosphorylation	1
pi3k	1
polypharmacology	1
promiscuity	1
protease	1
proteinligand	1
ptp	1
purine	1
reference	1
screen	1
sea	1
visualization	1
wljorgensen	1

Tag drugdiscovery [102 articles] Export

Related Tags