Tag inhibitor [at least 200 articles] Export

Recent papers classified by the tag inhibitor.

	Tyrosine kinase inhibitors and the dawn of molecular cancer therapeutics. [My Copy] Annual review of pharmacology and toxicology, Vol. 45 (2005), pp. 357-384. by Raoul Tibes, Jonathan Trent, Razelle Kurzrock posted to tyrk inhibitor cancer by guhjy on 2009-11-26 02:02:15 as
	Small-molecule inhibitors of PDK1. [My Copy] ChemMedChem, Vol. 3, No. 12. (December 2008), pp. 1810-1838. by Christian Peifer, Dario R. Alessi posted to pdk inhibitor by guhjy on 2009-11-25 09:30:59 as
	4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: potent and selective p70S6 kinase inhibitors. [My Copy] Bioorganic & medicinal chemistry letters, Vol. 19, No. 17. (1 September 2009), pp. 5191-5194. by Upul Bandarage, Brian Hare, Jonathan Parsons, et al.Ly Pham, Craig Marhefka, Guy Bemis, Qing Tang, Cameron Stuver S. Moody, Steve Rodems, Sundeep Shah, Chris Adams, Jose Bravo, Emmanuelle Charonnet, Vladimir Savic, Jon H. Come, Jeremy Green posted to s6k inhibitor by guhjy on 2009-11-25 04:37:01 as
	Attacking cancer at its foundation. [My Copy] Nature medicine, Vol. 15, No. 10. (October 2009), pp. 1153-1157. by Nicholas Lydon posted to kinase inhibitor imatinib cancer by guhjy on 2009-11-25 02:23:16 as
	Selective antagonism of anticancer drugs for side-effect removal. [My Copy] Trends in pharmacological sciences, Vol. 30, No. 8. (11 August 2009), pp. 403-410. by Ariel Fernández, Sean Sessel posted to kinase inhibitor cancer by guhjy on 2009-11-25 02:21:47 as
	An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer. [My Copy] Nature, Vol. 458, No. 7239. (9 April 2009), pp. 732-736. by Teresa A. Soucy, Peter G. Smith, Michael A. Milhollen, et al.Allison J. Berger, James M. Gavin, Sharmila Adhikari, James E. Brownell, Kristine E. Burke, David P. Cardin, Stephen Critchley, Courtney A. Cullis, Amanda Doucette, James J. Garnsey, Jeffrey L. Gaulin, Rachel E. Gershman, Anna R. Lublinsky, Alice McDonald, Hirotake Mizutani, Usha Narayanan, Edward J. Olhava, Stephane Peluso, Mansoureh Rezaei, Michael D. Sintchak, Tina Talreja, Michael P. Thomas, Tary Traore, Stepan Vyskocil, Gabriel S. Weatherhead, Jie Yu, Julie Zhang, Lawrence R. Dick, Christopher F. Claiborne, Mark Rolfe, Joseph B. Bolen, Steven P. Langston posted to nedd kinase inhibitor cancer by guhjy on 2009-11-25 02:19:45 as along with 3 people renatomilani absterga jbhiatt
	A competitive inhibitor traps LeuT in an open-to-out conformation. [My Copy] Science (New York, N.Y.), Vol. 322, No. 5908. (12 December 2008), pp. 1655-1661. by Satinder K. Singh, Chayne L. Piscitelli, Atsuko Yamashita, Eric Gouaux posted to structure membrane_proteins kinetics inhibitor channels carriers by martainn on 2009-11-23 15:59:55 as along with 1 person tprpip
	Selective cyclin-dependent kinase inhibitors discriminating between cell cycle and transcriptional kinases: future reality or utopia? [My Copy] Annals of the New York Academy of Sciences, Vol. 1171, No. 1. (August 2009), pp. 228-241. by Józefa Wesierska-Gadek, Vladimír Krystof posted to inhibitor cdk by guhjy on 2009-11-23 10:40:59 as
	Measuring and interpreting the selectivity of protein kinase inhibitors. [My Copy] Journal of chemical biology, Vol. 2, No. 3. (August 2009), pp. 131-151. by Lynette A. Smyth, Ian Collins posted to kinase inhibitor by guhjy on 2009-11-22 10:01:13 as
	BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo. [My Copy] The Biochemical journal, Vol. 401, No. 1. (1 January 2007), pp. 29-38. by Gopal P. Sapkota, Lorna Cummings, Felicity S. Newell, et al.Christopher Armstrong, Jennifer Bain, Morten Frodin, Matthias Grauert, Matthias Hoffmann, Gisela Schnapp, Martin Steegmaier, Philip Cohen, Dario R. Alessi posted to rsk inhibitor by guhjy on 2009-11-22 09:45:10 as
	Effects of a novel RSK inhibitor on α1-adrenergic regulation of myocardial NHE1 [My Copy] Journal of Molecular and Cellular Cardiology, Vol. 42, No. 6. (June 2007), pp. S46-S47. by F. Cuello, A. Snabaitis, M. Cohen, J. Taunton, M. Avkiran posted to rsk inhibitor by guhjy on 2009-11-22 09:34:30 as
	Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation. [My Copy] Cancer research, Vol. 65, No. 3. (1 February 2005), pp. 1027-1034. by Jeffrey A. Smith, Celeste E. Poteet-Smith, Yaming Xu, Timothy M. Errington, Sidney M. Hecht, Deborah A. Lannigan posted to rsk inhibitor by guhjy on 2009-11-22 09:28:58 as
	A clickable inhibitor reveals context-dependent autoactivation of p90 RSK. [My Copy] Nature chemical biology, Vol. 3, No. 3. (28 March 2007), pp. 156-160. by Michael S. Cohen, Haralambos Hadjivassiliou, Jack Taunton posted to rsk inhibitor by guhjy on 2009-11-22 09:26:16 as along with 1 person kokphinchooi
	Discovery of Potent and Selective Inhibitors of the Mammalian Target of Rapamycin (mTOR) Kinase. [My Copy] Journal of medicinal chemistry, Vol. 52, No. 22. (26 November 2009), pp. 7081-7089. by Pawel Nowak, Derek C. Cole, Natasja Brooijmans, et al.Matthew G. Bursavich, Kevin J. Curran, John W. Ellingboe, James J. Gibbons, Irwin Hollander, Yongbo Hu, Joshua Kaplan, David J. Malwitz, Lourdes Toral-Barza, Jeroen C. Verheijen, Arie Zask, Wei-Guo G. Zhang, Ker Yu posted to mtor inhibitor by guhjy on 2009-11-22 08:24:06 as
	Targeting RSK: an overview of small molecule inhibitors. [My Copy] Anti-cancer agents in medicinal chemistry, Vol. 8, No. 7. (October 2008), pp. 710-716. by Tam Luong L. Nguyen posted to rsk inhibitor by guhjy on 2009-11-22 08:23:47 as
	Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR). [My Copy] The Biochemical journal, Vol. 421, No. 1. (1 July 2009), pp. 29-42. by Juan M. García-Martínez, Jennifer Moran, Rosemary G. Clarke, et al.Alex Gray, Sabina C. Cosulich, Christine M. Chresta, Dario R. Alessi posted to mtor inhibitor 1 by guhjy on 2009-11-22 08:18:11 as
	p38(MAPK): stress responses from molecular mechanisms to therapeutics. [My Copy] Trends in molecular medicine, Vol. 15, No. 8. (06 August 2009), pp. 369-379. by Lydia R. Coulthard, Danielle E. White, Dominic L. Jones, Michael F. McDermott, Susan A. Burchill posted to p38 inhibitor by guhjy on 2009-11-21 15:34:00 as
	Synergistic anti-tumor efficacy of lovastatin and protein kinase C-beta inhibitor in hepatocellular carcinoma. [My Copy] Cancer chemotherapy and pharmacology, Vol. 64, No. 3. (August 2009), pp. 497-507. by Won Kim, Jung-Hwan H. Yoon, Jung-Ryul R. Kim, et al.In-Jin J. Jang, Yung-Jue J. Bang, Yoon-Jun J. Kim, Hyo-Suk S. Lee posted to statin pkc inhibitor hcc by guhjy on 2009-11-21 14:34:13 as
	Inhibition of phosphatidylinositol 3-kinase signaling in hepatic stellate cells blocks the progression of hepatic fibrosis. [My Copy] Hepatology (Baltimore, Md.), Vol. 50, No. 5. (November 2009), pp. 1512-1523. by Gakuhei Son, Ian N. Hines, Jeff Lindquist, Laura W. Schrum, Richard A. Rippe posted to pi3k lc inhibitor in hsc by guhjy on 2009-11-21 14:33:58 as
	Synergistic Anti-Fibrotic Efficacy of Statin and Protein Kinase C Inhibitor in Hepatic Fibrosis. [My Copy] American journal of physiology. Gastrointestinal and liver physiology (12 November 2009) by Jong In I. Yang, Jung-Hwan H. Yoon, Yung-Jue J. Bang, et al.Sung-Hee H. Lee, Soo-Mi M. Lee, Hee Jin J. Byun, Sun-Jung J. Myung, Won Kim, Hyo-Suk S. Lee posted to statin pkc lc inhibitor by guhjy on 2009-11-21 14:32:04 as
	A role for thrombin in the initiation of the immune response to therapeutic factor VIII [My Copy] Blood, Vol. 114, No. 21. (19 November 2009), pp. 4741-4748. by Jonathan Skupsky, Ai-Hong Zhang, Yan Su, David W. Scott posted to inhibitor by salitm on 2009-11-19 19:48:20 as
	Direct inhibition of the NOTCH transcription factor complex [My Copy] Nature, Vol. 462, No. 7270. (12 November 2009), pp. 182-188. by Raymond E. Moellering, Melanie Cornejo, Tina N. Davis, et al.Cristina D. Bianco, Jon C. Aster, Stephen C. Blacklow, Andrew L. Kung, D. Gary Gilliland, Gregory L. Verdine, James E. Bradner posted to transcription-factor structure pathway notch leukemia inhibitor by renatomilani on 2009-11-16 18:58:48 as along with 3 people gbloeb qshao cchand
	The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease. [My Copy] Nature reviews. Molecular cell biology, Vol. 8, No. 11. (November 2007), pp. 904-916. by Kun Ping P. Lu, Xiao Zhen Z. Zhou posted to structure pro-isomerization inhibitor by martainn on 2009-11-16 12:44:54 as
	Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity. [My Copy] Cellular and molecular life sciences : CMLS (12 November 2009) by C. Hahmann, T. Schroeter posted to rho inhibitor by guhjy on 2009-11-16 02:49:15 as
	V1\|[sol]\|V2 Vasopressin receptor antagonism potentiates the renoprotection of renin\|[ndash]\|angiotensin system inhibition in rats with renal mass reduction [My Copy] Kidney International, Vol. 76, No. 9. (22 July 2009), pp. 960-967. by Norberto Perico, Carla Zoja, Daniela Corna, et al.Daniela Rottoli, Flavio Gaspari, Lloyd Haskell, Giuseppe Remuzzi posted to snx rat inhibitor arb adh acei by guhjy on 2009-11-15 03:58:37 as
	Inhibitors of type 2 sodium glucose co-transporters--a new strategy for diabetes treatment. [My Copy] Pharmacological reports : PR, Vol. 61, No. 5. (t 2009), pp. 778-784. by Aleksandra Bołdys, Bogusław Okopień posted to sglt inhibitor dm by guhjy on 2009-11-15 03:24:44 as
	Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin. [My Copy] Cancer research, Vol. 69, No. 15. (1 August 2009), pp. 6232-6240. by Ker Yu, Lourdes Toral-Barza, Celine Shi, et al.Wei-Guo G. Zhang, Judy Lucas, Boris Shor, Jamie Kim, Jeroen Verheijen, Kevin Curran, David J. Malwitz, Derek C. Cole, John Ellingboe, Semiramis Ayral-Kaloustian, Tarek S. Mansour, James J. Gibbons, Robert T. Abraham, Pawel Nowak, Arie Zask posted to mtor inhibitor by guhjy on 2009-11-14 04:52:38 as
	Inhibitor hijacking of Akt activation [My Copy] Nature Chemical Biology, Vol. 5, No. 7. (24 May 2009), pp. 484-493. by Tatsuya Okuzumi, Dorothea Fiedler, Chao Zhang, et al.Daniel C. Gray, Brian Aizenstein, Randy Hoffman, Kevan M. Shokat posted to inhibitor akt by guhjy on 2009-11-14 04:49:03 as along with 1 person renatomilani
	Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases [My Copy] Nature Chemical Biology, Vol. 4, No. 11. (12 October 2008), pp. 691-699. by Beth Apsel, Jimmy A. Blair, Beatriz Gonzalez, et al.Tamim M. Nazif, Morri E. Feldman, Brian Aizenstein, Randy Hoffman, Roger L. Williams, Kevan M. Shokat, Zachary A. Knight posted to mtorc2 mtor inhibitor akt by guhjy on 2009-11-14 04:48:56 as along with 2 people richardbickerton ramensky
	Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. [My Copy] PLoS biology, Vol. 7, No. 2. (10 February 2009), e38. by Morris E. Feldman, Beth Apsel, Aino Uotila, et al.Robbie Loewith, Zachary A. Knight, Davide Ruggero, Kevan M. Shokat posted to rapamycin mtorc2 mtor inhibitor 1 by guhjy on 2009-11-14 04:43:42 as along with 1 person renatomilani
	Optimal targeting of the mTORC1 kinase in human cancer. [My Copy] Current opinion in cell biology, Vol. 21, No. 2. (April 2009), pp. 219-229. by Heidi A. Lane, Madlaina Breuleux posted to mtorc1 mtor inhibitor cancer by guhjy on 2009-11-13 02:14:36 as
	Targeting the EGFR and the PKB pathway in cancer. [My Copy] Current opinion in cell biology, Vol. 21, No. 2. (April 2009), pp. 185-193. by Shoshana Klein, Alexander Levitzki posted to rsk inhibitor egfr cancer akt by guhjy on 2009-11-13 02:13:33 as
	Current status and challenges associated with targeting mTOR for cancer therapy. [My Copy] BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, Vol. 23, No. 2. (2009), pp. 77-91. by Ryan J. Dowling, Michael Pollak, Nahum Sonenberg posted to mtor inhibitor cancer by guhjy on 2009-11-13 02:13:07 as
	Design, synthesis and selection of DNA-encoded small-molecule libraries. [My Copy] Nature chemical biology, Vol. 5, No. 9. (02 September 2009), pp. 647-654. by Matthew A. Clark, Raksha A. Acharya, Christopher C. Arico-Muendel, et al.Svetlana L. Belyanskaya, Dennis R. Benjamin, Neil R. Carlson, Paolo A. Centrella, Cynthia H. Chiu, Steffen P. Creaser, John W. Cuozzo, Christopher P. Davie, Yun Ding, G. Joseph Franklin, Kurt D. Franzen, Malcolm L. Gefter, Steven P. Hale, Nils J. Hansen, David I. Israel, Jinwei Jiang, Malcolm J. Kavarana, Michael S. Kelley, Christopher S. Kollmann, Fan Li, Kenneth Lind, Sibongile Mataruse, Patricia F. Medeiros, Jeffrey A. Messer, Paul Myers, Heather O'Keefe, Matthew C. Oliff, Cecil E. Rise, Alexander L. Satz, Steven R. Skinner, Jennifer L. Svendsen, Lujia Tang, Kurt van Vloten, Richard W. Wagner, Gang Yao, Baoguang Zhao, Barry A. Morgan posted to ma kinase inhibitor by guhjy on 2009-11-13 02:01:19 as along with 1 person Yanno
	Factors underlying sensitivity of cancers to small-molecule kinase inhibitors. [My Copy] Nature reviews. Drug discovery, Vol. 8, No. 9. (24 September 2009), pp. 709-723. by Pasi A. Jänne, Nathanael Gray, Jeff Settleman posted to kinase inhibitor cancer by guhjy on 2009-11-13 02:00:24 as along with 3 people kokphinchooi TimRooney renatomilani
	Discovery and development of aurora kinase inhibitors as anticancer agents. [My Copy] Journal of medicinal chemistry, Vol. 52, No. 9. (14 May 2009), pp. 2629-2651. by John R. Pollard, Michael Mortimore posted to kinase inhibitor aurora by guhjy on 2009-11-13 02:00:19 as
	Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics. [My Copy] Molecular & cellular proteomics : MCP (3 August 2009) by Cuiping Pan, Jesper V. Olsen, Henrik Daub, Matthias Mann posted to silac phosphoproteomics kinase inhibitor by guhjy on 2009-11-12 09:18:49 as along with 1 person brianb
	Targeting mTOR globally in cancer: Thinking beyond rapamycin. [My Copy] Cell cycle (Georgetown, Tex.), Vol. 8, No. 23. (14 December 2009) by Boris Shor, James J. Gibbons, Robert T. Abraham, Ker Yu posted to rapamycin mtorc2 mtor inhibitor cancer by guhjy on 2009-11-12 06:31:26 as
	Targeting mTOR with rapamycin: one dose does not fit all. [My Copy] Cell cycle (Georgetown, Tex.), Vol. 8, No. 7. (1 April 2009), pp. 1026-1029. by David A. Foster, Alfredo Toschi posted to rapamycin phosphatidic-acid mtorc2 mtorc1 mtor inhibitor cancer 1 by guhjy on 2009-11-12 05:01:33 as
	Aldosterone Blockade in Diabetic Nephropathy: Relative Risks and Potential Promise. [My Copy] Journal of the American Society of Nephrology : JASN (29 October 2009) by Mario F. Rubin, Raymond R. Townsend posted to inhibitor dn aldosterone by guhjy on 2009-11-11 04:35:38 as
	Apocynin: molecular aptitudes. [My Copy] Mediators of inflammation, Vol. 2008 (2008) by J. Stefanska, R. Pawliczak posted to nox inhibitor by guhjy on 2009-11-10 02:45:04 as
	Mineralocorticoid Receptor Blockers and Chronic Kidney Disease [My Copy] Clin J Am Soc Nephrol, Vol. 4, No. 10. (1 October 2009), pp. 1685-1691. by Gaurav Jain, Ruth C. Campbell, David G. Warnock posted to inhibitor ckd aldosterone by guhjy on 2009-11-08 10:10:34 as
	Blood pressure-independent reduction in proteinuria and arterial stiffness after acute endothelin-a receptor antagonism in chronic kidney disease. [My Copy] Hypertension, Vol. 54, No. 1. (1 July 2009), pp. 113-119. by Neeraj Dhaun, Iain M. Macintyre, Vanessa Melville, et al.Pajaree Lilitkarntakul, Neil R. Johnston, Jane Goddard, David J. Webb posted to rct inhibitor et ckd bp by guhjy on 2009-11-08 09:14:15 as
	High-resolution structure of Ascaris trypsin inhibitor in solution: direct evidence for a pH-induced conformational transition in the reactive site. [My Copy] Structure, Vol. 2, No. 7. (15 July 1994), pp. 669-678. by B. L. Grasberger, G. M. Clore, A. M. Gronenborn posted to solution-structure nmr inhibitor disulfide by bmduggan on 2009-11-07 05:33:13 as
	The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase. [My Copy] Structure, Vol. 2, No. 7. (15 July 1994), pp. 679-689. by K. Huang, N. C. Strynadka, V. D. Bernard, R. J. Peanasky, M. N. James posted to inhibitor disulfide crystal-structure by bmduggan on 2009-11-07 05:32:21 as
	NMR solution structure of Apis mellifera chymotrypsin/cathepsin G inhibitor-1 (AMCI-1): structural similarity with Ascaris protease inhibitors. [My Copy] Protein Science, Vol. 9, No. 5. (May 2000), pp. 976-984. by T. Cierpicki, J. Bania, J. Otlewski posted to solution-structure nmr inhibitor disulfide by bmduggan on 2009-11-07 05:30:41 as along with 2 people and 1 group thegoose2 tharris C. elegans / WormBase
	Solution structure of BSTI: a new trypsin inhibitor from skin secretions of Bombina bombina. [My Copy] Biochemistry, Vol. 40, No. 15. (17 April 2001), pp. 4601-4609. by K. J. Rosengren, N. L. Daly, M. J. Scanlon, D. J. Craik posted to solution-structure nmr inhibitor disulfide by bmduggan on 2009-11-07 05:29:12 as
	Selecting optimal second-line tyrosine kinase inhibitor therapy for chronic myeloid leukemia patients after imatinib failure - does the BCR-ABL mutation status really matter? [My Copy] Blood (30 October 2009), blood-2009-08-215939. by Susan Branford, Junia V. Melo, Timothy P. Hughes posted to leukemia inhibitor abl by renatomilani on 2009-11-06 02:02:06 as along with 1 person LeslieMudd
	Inhibitors of Factor VIIa/Tissue Factor [My Copy] Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 27, No. 9. (1 September 2007), pp. 1895-1900. by Rebecca A. Shirk, George P. Vlasuk posted to tissuefactor review inhibitor factorvii by bmduggan on 2009-11-04 20:31:08 as
	<I>In silico</I> prediction and screening of gamma-secretase inhibitors by molecular descriptors and machine learning methods [My Copy] Journal of Computational Chemistry, Vol. 9999, No. 9999. (2009), NA. by Xue-Gang Yang, Wei Lv, Yu-Zong Chen, Ying Xue posted to svm nov09 molecular_descriptors machine_learning jcc inhibitor gamma-secretase by klexa on 2009-11-04 15:37:14 as along with 1 person iskathy

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cancer	85
kinase	66
egfr	43
review	37
dn	35
drug	33
structure	25
phosphatase	24
tgfb	23
rat	20
akt	17
cdk	17
nsclc	17
erbb2	16
fibrosis	16
hcv	16
pkc	16
age	15
aromatase	15
ckd	14
mtor	14
p38	14
pi3k	14
virulence	14
breast	13
enzyme	12
hiv	12
iressa	12
mutation	12
resistance	12
signaling	12
apoptosis	11
dm	11
protein	11
drug-efflux	10
kidney	10
lc	10
proteasome	10
ptp1b	10
adh	9
angiotensin	9
mirna	9
mouse	9
receptor	9
vegf	9
cell-free	8
converting	8
hcc	8
histone	8
jnk	8
leukemia	8
pde	8
pdgf	8
protease	8
stz	8
tyrosine	8
c225	7
deacetylase	7
inflammation	7
mapk	7
peptidase	7
prostate	7
proteomics	7
rsk	7
sglt	7
3review	6
bcl-2	6
chemical	6
dipeptidyl	6
experiment	6
hdac	6
novel	6
nox	6
pp2a	6
rct	6
small	6
tyrk	6
ua	6
angioedema	5
aurora	5
channel	5
ck2	5
dbdb	5
dna	5
emt	5
fbl	5
iv	5
letrozole	5
methylation	5
nfkb	5
nmr	5
p	5
pharmacology	5
pt	5
ras	5
ref	5
rho	5
ros	5
substance	5
type-iii	5

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