Tag kinases [182 articles] Export

Recent papers classified by the tag kinases.

	WNK kinases and the control of blood pressure [My Copy] Pharmacology & Therapeutics, Vol. 106, No. 2. (May 2005), pp. 221-231. by G. Cope, A. Golbang, K. Oshaughnessy posted to wnk mgcb kinases hypertension by TimRooney on 2009-11-09 10:58:26 as
	The renal WNK kinase pathway: a new link to hypertension [My Copy] Nephrol. Dial. Transplant., Vol. 24, No. 4. (1 April 2009), pp. 1074-1077. by Ewout J. Hoorn, Nils van der Lubbe, Robert Zietse posted to wnk mgcb kinases hypertension by TimRooney on 2009-11-09 10:56:56 as
	Recent advances in glucokinase activators for the treatment of type 2 diabetes [My Copy] Drug Discovery Today, Vol. 14, No. 15-16. (09 August 2009), pp. 784-792. by Manojit Pal posted to mgcb kinases diabetes by TimRooney on 2009-11-09 10:43:38 as
	Protein kinase inhibitors: contributions from structure to clinical compounds [My Copy] Quarterly Reviews of Biophysics, Vol. 42, No. 01. (2009), pp. 1-40. by Louise N. Johnson posted to mgcb kinases drug_discovery by TimRooney on 2009-11-09 10:38:13 as along with 1 person saradtc
	Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease [My Copy] FEBS Letters, Vol. 582, No. 1. (09 January 2008), pp. 81-89. by D. Hardie posted to mgcb kinases diabetes by TimRooney on 2009-11-09 10:35:38 as
	Rapamune (RAPA, rapamycin, sirolimus): Mechanism of Action Immunosuppressive Effect Results From Blockade of Signal Transduction and Inhibition of Cell Cycle Progression [My Copy] Clinical Biochemistry, Vol. 39, No. 5. (May 2006), pp. 484-489. by Suren N. Sehgal posted to mgcb kinases immunosuppression by TimRooney on 2009-11-09 10:27:50 as
	Epidermal growth factor receptors as a target for cancer treatment: The emerging role of IMC-C225 in the treatment of lung and head and neck cancers [My Copy] Seminars in Oncology, Vol. 29, No. 1. (February 2002), pp. 27-36. by R. Herbst posted to mgcb kinases egfr cancer by kokphinchooi on 2009-11-06 05:51:20 as along with 2 people mat956 baraksch
	EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy [My Copy] Science, Vol. 304, No. 5676. (4 June 2004), pp. 1497-1500. by J. Guillermo Paez, Pasi A. Janne, Jeffrey C. Lee, et al.Sean Tracy, Heidi Greulich, Stacey Gabriel, Paula Herman, Frederic J. Kaye, Neal Lindeman, Titus J. Boggon, Katsuhiko Naoki, Hidefumi Sasaki, Yoshitaka Fujii, Michael J. Eck, William R. Sellers, Bruce E. Johnson, Matthew Meyerson posted to nonsmall_cell_lung_cancer mgcb kinases gefitinib egfr biological_action by kokphinchooi on 2009-11-06 05:47:51 as
	An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor [My Copy] Cell, Vol. 125, No. 6. (13 June 2006), pp. 1137-1149. by X. Zhang, J. Gureasko, K. Shen, P. Cole, J. Kuriyan posted to mgcb kinases erbb_family biological_action by kokphinchooi on 2009-11-06 05:12:47 as along with 2 people ubcg08l pjasper
	Mechanisms of Disease: oncogene addiction\|[mdash]\|a rationale for molecular targeting in cancer therapy [My Copy] Nature Clinical Practice Oncology, Vol. 3, No. 8. (01 August 2006), pp. 448-457. by I. Bernard Weinstein, Andrew K. Joe posted to mgcb kinases cited by saradtc on 2009-11-06 00:38:11 as along with 2 people jfr guhjy
	Mechanisms of specificity in protein phosphorylation [My Copy] Nature Reviews Molecular Cell Biology, Vol. 8, No. 7. (01 July 2007), pp. 530-541. by Jeffrey A. Ubersax, James E. Ferrell Jr posted to mgcb kinases general by kokphinchooi on 2009-11-05 23:44:32 as along with 6 people and 2 groups hryk coela guhjy dchughes Evangelia oelemento G4ID Genetics-of-Gambling
	The Protein Kinase Complement of the Human Genome [My Copy] Science, Vol. 298, No. 5600. (6 December 2002), pp. 1912-1934. by G. Manning, D. B. Whyte, R. Martinez, T. Hunter, S. Sudarsanam posted to mgcb kinases cited by saradtc on 2009-11-05 21:06:07 as along with 14 people guhjy nedwards nzm catcremona Yanno ceolas tjimenez kuhn aqeel lenov Evangelia renatomilani taten daed
	Mechanisms of drug inhibition of signalling molecules [My Copy] Nature, Vol. 441, No. 7092. (24 May 2006), pp. 457-462. by Judith S. Sebolt-Leopold, Jessie M. English posted to mgcb kinases cited by saradtc on 2009-11-05 20:07:26 as along with 1 person allmensch
	Structural Basis for Allosteric Regulation of the Monomeric Allosteric Enzyme Human Glucokinase [My Copy] Structure, Vol. 12, No. 3. (March 2004), pp. 429-438. by Kenji Kamata, Morihiro Mitsuya, Teruyuki Nishimura, Jun-ichi Eiki, Yasufumi Nagata posted to mgcb kinases diabetes allosteric by TimRooney on 2009-11-05 09:32:34 as along with 2 people mittinatten lna
	The 4-anilinoquinazoline class of inhibitors of the erbB family of receptor tyrosine kinases [My Copy] Il Farmaco, Vol. 56, No. 1-2. (1 March 2001), pp. 51-56. by W. Denny posted to mgcb kinases egfr biological_action by kokphinchooi on 2009-11-04 19:14:39 as
	Review of epidermal growth factor receptor biology [My Copy] International Journal of Radiation OncologyBiologyPhysics, Vol. 59, No. 2. (June 2004), pp. S21-S26. by R. Herbst posted to mgcb kinases egfr biological_action by kokphinchooi on 2009-11-04 19:13:30 as
	Discovery of N-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays [My Copy] Journal of Medicinal Chemistry, Vol. 47, No. 27. (1 December 2004), pp. 6658-6661. by Louis J. Lombardo, Francis Y. Lee, Ping Chen, et al.Derek Norris, Joel C. Barrish, Kamelia Behnia, Stephen Castaneda, Lyndon A. M. Cornelius, Jagabandhu Das, Arthur M. Doweyko, Craig Fairchild, John T. Hunt, Ivan Inigo, Kathy Johnston, Amrita Kamath, David Kan, Herbert Klei, Punit Marathe, Suhong Pang, Russell Peterson, Sidney Pitt, Gary L. Schieven, Robert J. Schmidt, John Tokarski, Mei-Li Wen, John Wityak, Robert M. Borzilleri posted to mgcb kinases dasatinib by saradtc on 2009-11-04 15:07:24 as
	Editorial: Drug Discovery Process for Kinease Inhibitors [My Copy] ChemBioChem, Vol. 6, No. 3. (2005), pp. 455-459. by Hilmar Weinmann, Rainer Metternich posted to mgcb kinases by saradtc on 2009-11-04 14:52:16 as
	Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates. [My Copy] Journal of Biological Chemistry, Vol. 265, No. 3. (25 January 1990), pp. 1750-1754. by G. M. Walton, W. S. Chen, M. G. Rosenfeld, G. N. Gill posted to mgcb kinases egfr by kokphinchooi on 2009-11-04 14:50:47 as
	Protein Kinase Inhibitors: Insights into Drug Design from Structure [My Copy] Science, Vol. 303, No. 5665. (19 March 2004), pp. 1800-1805. by Martin E. M. Noble, Jane A. Endicott, Louise N. Johnson posted to mgcb kinases cited by saradtc on 2009-11-04 14:45:12 as along with 7 people guhjy Yanno tjimenez aqeel kummerj superpyrin nigham
	Molecular Recognition of Protein Kinase Binding Pockets for Design of Potent and Selective Kinase Inhibitors [My Copy] Journal of Medicinal Chemistry, Vol. 50, No. 3. (1 February 2007), pp. 409-424. by Jeffrey J. Liao posted to kinases cited by saradtc on 2009-11-04 14:24:53 as
	Five-Year Follow-up of Patients Receiving Imatinib for Chronic Myeloid Leukemia [My Copy] N Engl J Med, Vol. 355, No. 23. (7 December 2006), pp. 2408-2417. by Brian J. Druker, Francois Guilhot, Stephen G. O'Brien, et al.Insa Gathmann, Hagop Kantarjian, Norbert Gattermann, Michael W. N. Deininger, Richard T. Silver, John M. Goldman, Richard M. Stone, Francisco Cervantes, Andreas Hochhaus, Bayard L. Powell, Janice L. Gabrilove, Philippe Rousselot, Josy Reiffers, Jan J. Cornelissen, Timothy Hughes, Hermine Agis, Thomas Fischer, Gregor Verhoef, John Shepherd, Giuseppe Saglio, Alois Gratwohl, Johan L. Nielsen, Jerald P. Radich, Bengt Simonsson, Kerry Taylor, Michele Baccarani, Charlene So, Laurie Letvak, Richard A. Larson, the IRIS Investigators posted to mgcb kinases cited by saradtc on 2009-11-04 14:02:58 as along with 3 people acrystal waghsk Amazoness
	Untangling the ErbB signalling network [My Copy] Nature Reviews Molecular Cell Biology, Vol. 2, No. 2. (01 February 2001), pp. 127-137. by Yosef Yarden, Mark X. Sliwkowski posted to mgcb kinases erbb_family cancer by kokphinchooi on 2009-11-04 14:02:27 as
	Charging it up: global analysis of protein phosphorylation [My Copy] Trends in Genetics, Vol. 22, No. 10. (12 October 2006), pp. 545-554. by J. Ptacek, M. Snyder posted to mgcb kinases cited by saradtc on 2009-11-04 12:00:34 as along with 4 people guhjy koller neils carlk
	Protein phosphorylation in signaling – 50 years and counting [My Copy] Trends in Biochemical Sciences, Vol. 30, No. 6. (June 2005), pp. 286-290. by Tony Pawson, John D. Scott posted to mgcb kinases cited by saradtc on 2009-11-04 10:41:30 as along with 2 people hryk guhjy
	A probability-based approach for high-throughput protein phosphorylation analysis and site localization [My Copy] Nature Biotechnology, Vol. 24, No. 10. (10 September 2006), pp. 1285-1292. by Sean A. Beausoleil, Judit Villen, Scott A. Gerber, John Rush, Steven P. Gygi posted to mgcb kinases cited by saradtc on 2009-11-04 10:36:33 as along with 6 people alexgeorgiou guhjy wnpx csardas Ao_Li2007 Thomasah
	Optimization of 6,7-Disubstituted-4-(arylamino)quinoline-3-carbonitriles as Orally Active, Irreversible Inhibitors of Human Epidermal Growth Factor Receptor-2 Kinase Activity [My Copy] Journal of Medicinal Chemistry, Vol. 48, No. 4. (1 February 2005), pp. 1107-1131. by Hwei-Ru Tsou, Elsebe G. Overbeek-Klumpers, William A. Hallett, et al.Marvin F. Reich, M. Brawner Floyd, Bernard D. Johnson, Ronald S. Michalak, Ramaswamy Nilakantan, Carolyn Discafani, Jonathan Golas, Sridhar K. Rabindran, Ru Shen, Xiaoqing Shi, Yu-Fen Wang, Janis Upeslacis, Allan Wissner posted to scifinder sar mgcb kinases egfr convalent_inhibitor cancer by kokphinchooi on 2009-11-04 09:45:30 as
	Emerging drugs for non-small-cell lung cancer [My Copy] Expert Opinion on Emerging Drugs, Vol. 12, No. 3. (September 2007), pp. 449-460. by Enriqueta Felip, Mariacarmela Santarpia, Rafael Rosell posted to small_cell_lung_cancer mgcb kinases by kokphinchooi on 2009-11-03 23:10:15 as
	EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. [My Copy] The New England journal of medicine, Vol. 352, No. 8. (24 February 2005), pp. 786-792. by Susumu Kobayashi, Titus J. Boggon, Tajhal Dayaram, et al.Pasi A. Jänne, Olivier Kocher, Matthew Meyerson, Bruce E. Johnson, Michael J. Eck, Daniel G. Tenen, Balázs Halmos posted to scifinder mgcb kinases egfr convalent_inhibitor cl-387785 cancer by kokphinchooi on 2009-11-03 19:02:41 as along with 1 person mat956
	Resistance to an Irreversible Epidermal Growth Factor Receptor (EGFR) Inhibitor in EGFR-Mutant Lung Cancer Reveals Novel Treatment Strategies [My Copy] Cancer Res, Vol. 67, No. 21. (1 November 2007), pp. 10417-10427. by Zhiwei Yu, Titus J. Boggon, Susumu Kobayashi, et al.Cheng Jin, Patrick C. Ma, Afshin Dowlati, Jeffrey A. Kern, Daniel G. Tenen, Balazs Halmos posted to scifinder kinases egfr convalent_inhibitor cl-387785 cancer by kokphinchooi on 2009-11-03 18:52:51 as
	Dual MET\|[ndash]\|EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer [My Copy] British Journal of Cancer, Vol. 99, No. 6. (26 August 2008), pp. 911-922. by Z. Tang, R. Du, S. Jiang, et al.C. Wu, D. S. Barkauskas, J. Richey, J. Molter, M. Lam, C. Flask, S. Gerson, A. Dowlati, L. Liu, Z. Lee, B. Halmos, Y. Wang, J. A. Kern, P. C. Ma posted to scifinder mgcb kinases egfr convalent_inhibitor cl-387785 cancer by kokphinchooi on 2009-11-03 18:42:47 as
	Dasatinib in Imatinib-Resistant Philadelphia Chromosome-Positive Leukemias [My Copy] N Engl J Med, Vol. 354, No. 24. (15 June 2006), pp. 2531-2541. by Moshe Talpaz, Neil P. Shah, Hagop Kantarjian, et al.Nicholas Donato, John Nicoll, Ron Paquette, Jorge Cortes, Susan O'Brien, Claude Nicaise, Eric Bleickardt, M. Anne Blackwood-Chirchir, Vishwanath Iyer, Tai-Tsang Chen, Fei Huang, Arthur P. Decillis, Charles L. Sawyers posted to mgcb kinases dasatinib cited by saradtc on 2009-11-03 18:13:21 as
	Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy [My Copy] Blood, Vol. 109, No. 6. (15 March 2007), pp. 2303-2309. by Andreas Hochhaus, Hagop M. Kantarjian, Michele Baccarani, et al.Jeffrey H. Lipton, Jane F. Apperley, Brian J. Druker, Thierry Facon, Stuart L. Goldberg, Francisco Cervantes, Dietger Niederwieser, Richard T. Silver, Richard M. Stone, Timothy P. Hughes, Martin C. Muller, Rana Ezzeddine, Athena M. Countouriotis, Neil P. Shah posted to mgcb kinases dasatinib cited by saradtc on 2009-11-03 18:12:03 as
	A Differential Requirement for the COOH-terminal Region of the Epidermal Growth Factor (EGF) Receptor in Amphiregulin and EGF Mitogenic Signaling [My Copy] Journal of Biological Chemistry, Vol. 274, No. 13. (26 March 1999), pp. 8900-8909. by Lily Wong, Tushar B. Deb, Stewart A. Thompson, Alan Wells, Gibbes R. Johnson posted to mgcb kinases egfr biological_action by kokphinchooi on 2009-11-03 13:00:50 as
	The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies [My Copy] Cancer Cell, Vol. 9, No. 6. (13 June 2006), pp. 485-495. by Hongbin Ji, Danan Li, Liang Chen, et al.Takeshi Shimamura, Susumu Kobayashi, Kate McNamara, Umar Mahmood, Albert Mitchell, Yangping Sun, Ruqayyah Al-Hashem posted to scifinder neratinib mgcb kinases egfr convalent_inhibitor by kokphinchooi on 2009-11-03 12:23:58 as
	Dual inhibition of ErbB1 (EGFR/HER1) and ErbB2 (HER2/neu) [My Copy] European Journal of Cancer, Vol. 43, No. 3. (February 2007), pp. 481-489. by A. Reid, L. Vidal, H. Shaw, J. Debono posted to scifinder neratinib mgcb kinases egfr convalent_inhibitor by kokphinchooi on 2009-11-03 12:22:33 as along with 1 person pjasper
	Second-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer [My Copy] Oncologist, Vol. 12, No. 3. (1 March 2007), pp. 325-330. by Lecia V. Sequist posted to scifinder neratinib mgcb kinases egfr convalent_inhibitor by kokphinchooi on 2009-11-03 12:19:10 as along with 1 person pjasper
	HKI-272 in NonâSmall Cell Lung Cancer [My Copy] Clinical Cancer Research, Vol. 13, No. 15. (1 August 2007), pp. 4593s-4596s. by Kwok-Kin Wong posted to scifinder neratinib mgcb kinases convalent_inhibitor by kokphinchooi on 2009-11-03 12:18:30 as
	The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP [My Copy] Proceedings of the National Academy of Sciences, Vol. 105, No. 6. (12 February 2008), pp. 2070-2075. by Cai-Hong Yun, Kristen E. Mengwasser, Angela V. Toms, et al.Michele S. Woo, Heidi Greulich, Kwok-Kin Wong, Matthew Meyerson, Michael J. Eck posted to scifinder neratinib mgcb kinases egfr convalent_inhibitor by kokphinchooi on 2009-11-03 12:09:53 as
	The Development of HKI-272 and Related Compounds for the Treatment of Cancer [My Copy] Archiv der Pharmazie, Vol. 341, No. 8. (August 2008), pp. 465-477. by Allan Wissner, Tarek S. Mansour posted to scifinder neratinib mgcb kinases convalent_inhibitor by kokphinchooi on 2009-11-03 12:03:33 as
	Computational Studies of Epidermal Growth Factor Receptor: Docking Reliability, Three-Dimensional Quantitative Structure−Activity Relationship Analysis, and Virtual Screening Studies [My Copy] Journal of Medicinal Chemistry, Vol. 52, No. 4. (26 February 2009), pp. 964-975. by Concettina La Motta, Stefania Sartini, Tiziano Tuccinardi, Erika Nerini, Federico Da Settimo, Adriano Martinelli posted to scifinder neratinib mgcb kinases convalent_inhibitor by kokphinchooi on 2009-11-03 11:56:19 as
	A Phase I Study with Neratinib (HKI-272), an Irreversible Pan ErbB Receptor Tyrosine Kinase Inhibitor, in Patients with Solid Tumors [My Copy] Clinical Cancer Research, Vol. 15, No. 7. (1 April 2009), pp. 2552-2558. by Kwok-K Wong, Paula M. Fracasso, Ronald M. Bukowski, et al.Thomas J. Lynch, Pamela N. Munster, Geoffrey I. Shapiro, Pasi A. JÃ¤nne, Joseph P. Eder, Michael J. Naughton, Matthew J. Ellis, Suzanne F. Jones, Tarek Mekhail, Charles Zacharchuk, Jennifer Vermette, Richat Abbas, Susan Quinn, Christine Powell, Howard A. Burris posted to scifinder neratinib mgcb kinases egfr convalent_inhibitor by kokphinchooi on 2009-11-03 11:55:19 as
	Structural Bioinformatics-Based Design of Selective, Irreversible Kinase Inhibitors [My Copy] Science, Vol. 308, No. 5726. (27 May 2005), pp. 1318-1321. by Michael S. Cohen, Chao Zhang, Kevan M. Shokat, Jack Taunton posted to mgcb kinases convalent_inhibitor by kokphinchooi on 2009-11-03 10:41:01 as along with 3 people BragilMassoud RJDReid MaggieYe
	A quantitative analysis of kinase inhibitor selectivity [My Copy] Nat Biotech, Vol. 26, No. 1. (08 January 2008), pp. 127-132. by Mazen W. Karaman, Sanna Herrgard, Daniel K. Treiber, et al.Paul Gallant, Corey E. Atteridge, Brian T. Campbell, Katrina W. Chan, Pietro Ciceri, Mindy I. Davis, Philip T. Edeen, Raffaella Faraoni, Mark Floyd, Jeremy P. Hunt, Daniel J. Lockhart, Zdravko V. Milanov, Michael J. Morrison, Gabriel Pallares, Hitesh K. Patel, Stephanie Pritchard, Lisa M. Wodicka, Patrick P. Zarrinkar posted to mgcb kinases cited by saradtc on 2009-11-03 10:00:47 as along with 7 people emmel Yanno guhjy tmmurali psique renatomilani hchmani
	A small molecule\|[ndash]\|kinase interaction map for clinical kinase inhibitors [My Copy] Nat Biotech, Vol. 23, No. 3. (13 February 2005), pp. 329-336. by Miles A. Fabian, William H. Biggs, Daniel K. Treiber, et al.Corey E. Atteridge, Mihai D. Azimioara, Michael G. Benedetti, Todd A. Carter, Pietro Ciceri, Philip T. Edeen, Mark Floyd, Julia M. Ford, Margaret Galvin, Jay L. Gerlach, Robert M. Grotzfeld, Sanna Herrgard, Darren E. Insko, Michael A. Insko, Andiliy G. Lai, Jean-Michel Lelias, Shamal A. Mehta, Zdravko V. Milanov, Anne M. Velasco, Lisa M. Wodicka, Hitesh K. Patel, Patrick P. Zarrinkar, David J. Lockhart posted to mgcb kinases cited by saradtc on 2009-11-03 09:59:50 as along with 7 people Yanno BragilMassoud tjimenez kuhn 7ofAnn seowu hchmani
	Inhibitors of Protein Kinase Signaling Pathways: Emerging Therapies for Cardiovascular Disease [My Copy] Circulation, Vol. 109, No. 10. (16 March 2004), pp. 1196-1205. by Thomas Force, Keisuke Kuida, Mark Namchuk, Keykavous Parang, John M. Kyriakis posted to mgcb kinases cited by saradtc on 2009-11-03 09:57:40 as
	Irreversible inhibitors of the erbB family of protein tyrosine kinases [My Copy] Pharmacology & Therapeutics, Vol. 93, No. 2-3. (March 2002), pp. 253-261. by W. Denny posted to mgcb kinases egfr convalent_inhibitor by kokphinchooi on 2009-11-02 23:05:14 as
	Allosteric inhibitors of Bcr-abl\|[ndash]\|dependent cell proliferation [My Copy] Nature Chemical Biology, Vol. 2, No. 2. (15 January 2006), pp. 95-102. by Francisco J. Adrian, Qiang Ding, Taebo Sim, et al.Anastasia Velentza, Christine Sloan, Yi Liu, Guobao Zhang, Wooyoung Hur, Sheng Ding, Paul Manley, Jurgen Mestan, Doriano Fabbro, Nathanael S. Gray posted to mgcb kinases cancer allosteric by TimRooney on 2009-11-02 18:19:55 as along with 1 person Yanno
	Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy [My Copy] Science, Vol. 301, No. 5631. (18 July 2003), pp. 370-373. by Joseph Grimsby, Ramakanth Sarabu, Wendy L. Corbett, et al.Nancy-Ellen Haynes, Fred T. Bizzarro, John W. Coffey, Kevin R. Guertin, Darryl W. Hilliard, Robert F. Kester, Paige E. Mahaney, Linda Marcus, Lida Qi, Cheryl L. Spence, John Tengi, Mark A. Magnuson, Chang A. Chu, Mark T. Dvorozniak, Franz M. Matschinsky, Joseph F. Grippo posted to mgcb kinases diabetes allosteric by TimRooney on 2009-11-02 18:17:20 as
	Studies leading to the identification of ZD1839 (iressa™): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer [My Copy] Bioorganic & Medicinal Chemistry Letters, Vol. 11, No. 14. (23 July 2001), pp. 1911-1914. by A. Barker posted to mgcb kinases egfr cancer by kokphinchooi on 2009-11-02 17:38:53 as

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mgcb	86
review	25
convalent_inhibitor	23
egfr	21
cancer	16
cited	15
immunology	14
allosteric	13
docking	13
scifinder	13
protein_structure	12
neratinib	9
pharmacology	9
screening	9
signalling	9
protein	8
kinase	7
md_simulation	7
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drug_discovery	6
protein_design	6
protein_dynamics	6
protein_sequence	6
2008	5
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ppi	4
sm	4
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2009	3
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cell	3
cl-387785	3
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genetics	3
hbond	3
ion_pairs	3
molecular_motors	3
nucleotide_analogues	3
phosphorylation	3
structure	3
tyrosine	3
alignment	2
apoptosis	2
chemical	2
consolidation	2
domain_motions	2
energyfunctions	2
erbb_family	2
factor	2
genome	2
hypertension	2
memory	2
metagenomics	2
peptides	2
phospho_peptides	2
polypharmacology	2
tcell	2
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immunosuppression	1
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kit	1
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receptor	1
sar	1
selectively	1
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t-lymphocytes	1
targeting	1
tax	1
trkc	1
water	1

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