Tag knockout-mouse [35 articles] Export Sort

Recent papers classified by the tag knockout-mouse.

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	DNA Damage-Induced Activation of p53 by the Checkpoint Kinase Chk2 [My Copy] Science, Vol. 287, No. 5459. (10 March 2000), pp. 1824-1827. by Atsushi Hirao, Young-Yun Kong, Shuhei Matsuoka, et al.Andrew Wakeham, Jürgen Ruland, Hiroki Yoshida, Dou Liu, Stephen J. Elledge, Tak W. Mak posted to chk2 knockout-mouse p53 by DNAReplication on 2008-02-03 20:32:17 as along with 2 people catcremona mkuzak
	Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. [My Copy] Nat Cell Biol, Vol. 5, No. 7. (July 2003), pp. 675-679. by A. Celeste, O. Fernandez-Capetillo, M. J. Kruhlak, et al.D. R. Pilch, D. W. Staudt, A. Lee, R. F. Bonner, W. M. Bonner, A. Nussenzweig posted to atm h2ax knockout-mouse by DNAReplication on 2008-02-02 22:44:20 as along with 1 person catcremona
	Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. [My Copy] Mol Cell Biol, Vol. 22, No. 18. (September 2002), pp. 6521-6532. by A. Hirao, A. Cheung, G. Duncan, et al.P. M. Girard, A. J. Elia, A. Wakeham, H. Okada, T. Sarkissian, J. A. Wong, T. Sakai, E. De Stanchina, R. G. Bristow, T. Suda, S. W. Lowe, P. A. Jeggo, S. J. Elledge, T. W. Mak posted to chk2 knockout-mouse by DNAReplication on 2008-01-30 20:32:38 as
	Cross-talk between Chk1 and Chk2 in double-mutant thymocytes. [My Copy] Proc Natl Acad Sci U S A, Vol. 104, No. 10. (6 March 2007), pp. 3805-3810. by K. Zaugg, Y. W. Su, P. T. Reilly, et al.Y. Moolani, C. C. Cheung, R. Hakem, A. Hirao, Q. Liu, S. J. Elledge, T. W. Mak posted to chk1 chk2 knockout-mouse by DNAReplication on 2008-01-08 20:13:30 as
	Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. [My Copy] Cell, Vol. 82, No. 4. (25 August 1995), pp. 675-684. by C. Deng, P. Zhang, J. W. Harper, S. J. Elledge, P. Leder posted to knockout-mouse p21 by DNAReplication on 2007-09-13 11:43:25 as along with 1 person Blo
	Ataxia Telangiectasia Mutated-Dependent Apoptosis after Genotoxic Stress in the Developing Nervous System Is Determined by Cellular Differentiation Status [My Copy] J. Neurosci., Vol. 21, No. 17. (1 September 2001), pp. 6687-6693. by Youngsoo Lee, Miriam J. Chong, Peter J. Mckinnon posted to atm damagedevelopment knockout-mouse by DNAReplication on 2007-09-01 19:00:02 as
	Pleiotropic defects in ataxia-telangiectasia protein-deficient mice [My Copy] PNAS, Vol. 93, No. 23. (12 November 1996), pp. 13084-13089. by Ari Elson, Yaoqi Wang, Cathie j Daugherty, et al.Cynthia c Morton, Fen Zhou, Juanita Campos-Torres, Philip Leder posted to atm damagedevelopment knockout-mouse by DNAReplication on 2007-08-29 20:05:32 as
	Synthetic lethality between mutation in Atm and DNA-PKcs during murine embryogenesis [My Copy] Current Biology, Vol. 11, No. 3. (6 February 2001), pp. 191-194. by Kay E. Gurley, Christopher J. Kemp posted to atm dna-pk knockout-mouse radiation-sensitivity synthetic-lethal by DNAReplication on 2007-08-21 16:18:24 as
	Hypersensitivity to DNA damage leads to increased apoptosis during early mouse development. [My Copy] Genes Dev, Vol. 14, No. 16. (15 August 2000), pp. 2072-2084. by B. S. Heyer, A. MacAuley, O. Behrendtsen, Z. Werb posted to atm ir knockout-mouse radiation-sensitivity by DNAReplication on 2007-08-21 16:10:12 as
	An essential function for NBS1 in the prevention of ataxia and cerebellar defects [My Copy] Nature Medicine, Vol. 11, No. 5. (10 April 2005), pp. 538-544. by Pierre-Olivier Frappart, Wei-Min Tong, Ilja Demuth, et al.Ivan Radovanovic, Zdenko Herceg, Adriano Aguzzi, Martin Digweed, Zhao-Qi Wang posted to knockout-mouse nbs1 by DNAReplication on 2007-08-20 22:00:24 as
	A Murine Model of Nijmegen Breakage Syndrome [My Copy] Current Biology, Vol. 12, No. 8. (16 April 2002), pp. 648-653. by Bret R. Williams, Olga K. Mirzoeva, William F. Morgan, Junyu Lin, Wesley Dunnick, John H. Petrini posted to atm knockout-mouse nbs1 synthetic-lethal by DNAReplication on 2007-08-20 20:43:29 as
	Requirement for Atm in Ionizing Radiation-Induced Cell Death in the Developing Central Nervous System [My Copy] Science, Vol. 280, No. 5366. (15 May 1998), pp. 1089-1091. by Karl-Heinz Herzog, Miriam J. Chong, Manuela Kapsetaki, James I. Morgan, Peter J. Mckinnon posted to atm knockout-mouse by DNAReplication on 2007-08-20 20:33:44 as
	Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice. [My Copy] Curr Biol, Vol. 11, No. 2. (23 January 2001), pp. 105-109. by J. Zhu, S. Petersen, L. Tessarollo, A. Nussenzweig posted to knockout-mouse nbs1 by DNAReplication on 2007-08-12 22:19:21 as
	Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation. [My Copy] Proc Natl Acad Sci U S A, Vol. 96, No. 13. (22 June 1999), pp. 7376-7381. by G. Luo, M. S. Yao, C. F. Bender, et al.M. Mills, A. R. Bladl, A. Bradley, J. H. Petrini posted to knockout-mouse rad50 by DNAReplication on 2007-08-12 22:18:39 as
	Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells. [My Copy] Nucleic Acids Res, Vol. 25, No. 15. (1 August 1997), pp. 2985-2991. by Y. Xiao, D. T. Weaver posted to knockout-mouse mre11 by DNAReplication on 2007-08-12 22:17:38 as
	Conditional inactivation of the mouse Hus1 cell cycle checkpoint gene. [My Copy] Genomics, Vol. 86, No. 2. (August 2005), pp. 212-224. by P. S. Levitt, H. Liu, C. Manning, R. S. Weiss posted to hus1 knockout-mouse by DNAReplication on 2007-08-11 19:05:24 as
	Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination. [My Copy] EMBO J, Vol. 23, No. 17. (1 September 2004), pp. 3548-3558. by M. Budzowska, I. Jaspers, J. Essers, et al.H. de Waard, E. van Drunen, K. Hanada, B. Beverloo, R. W. Hendriks, A. de Klein, R. Kanaar, J. H. Hoeijmakers, A. Maas posted to knockout-mouse rad17 radiation-sensitivity by DNAReplication on 2007-08-11 19:04:35 as
	Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. [My Copy] Proc Natl Acad Sci U S A, Vol. 93, No. 13. (25 June 1996), pp. 6236-6240. by T. Tsuzuki, Y. Fujii, K. Sakumi, et al.Y. Tominaga, K. Nakao, M. Sekiguchi, A. Matsushiro, Y. Yoshimura, MoritaT posted to knockout-mouse rad51 by DNAReplication on 2007-08-11 19:03:29 as
	A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53 [My Copy] Mol. Cell. Biol., Vol. 16, No. 12. (1 December 1996), pp. 7133-7143. by Ds Lim, P. Hasty posted to knockout-mouse rad51 by DNAReplication on 2007-08-11 19:02:36 as
	Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2. [My Copy] Nature, Vol. 386, No. 6627. (24 April 1997), pp. 804-810. by S. K. Sharan, M. Morimatsu, U. Albrecht, et al.D. S. Lim, E. Regel, C. Dinh, A. Sands, G. Eichele, P. Hasty, A. Bradley posted to brca2 knockout-mouse radiation-sensitivity by DNAReplication on 2007-08-11 18:58:42 as
	DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus [My Copy] Nat Genet, Vol. 17, No. 4. (December 1997), pp. 483-486. by Chamelli Jhappan, Herbert C. Morse, Robert D. Fleischmann, Michael M. Gottesman, Glenn Merlino posted to dna-pk knockout-mouse vdj-recombination by DNAReplication on 2007-08-11 18:43:04 as
	Brca2 is required for embryonic cellular proliferation in the mouse. [My Copy] Genes Dev, Vol. 11, No. 10. (15 May 1997), pp. 1242-1252. by A. Suzuki, J. L. de la Pompa, R. Hakem, et al.A. Elia, R. Yoshida, R. Mo, H. Nishina, T. Chuang, A. Wakeham, A. Itie, W. Koo, P. Billia, A. Ho, M. Fukumoto, C. C. Hui, T. W. Mak posted to brca2 knockout-mouse by DNAReplication on 2007-08-11 18:40:44 as
	The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse. [My Copy] Cell, Vol. 85, No. 7. (28 June 1996), pp. 1009-1023. by R. Hakem, J. L. de la Pompa, C. Sirard, et al.R. Mo, M. Woo, A. Hakem, A. Wakeham, J. Potter, A. Reitmair, F. Billia, E. Firpo, C. C. Hui, J. Roberts, J. Rossant, T. W. Mak posted to brca1 knockout-mouse by DNAReplication on 2007-08-11 18:39:56 as
	Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress [My Copy] Genes Dev., Vol. 14, No. 15. (1 August 2000), pp. 1886-1898. by Robert S. Weiss, Tamar Enoch, Philip Leder posted to hus1 knockout-mouse p21 by DNAReplication on 2007-08-04 22:00:02 as
	Short Telomeres and Ataxia-Telangiectasia Mutated Deficiency Cooperatively Increase Telomere Dysfunction and Suppress Tumorigenesis [My Copy] Cancer Res, Vol. 63, No. 23. (1 December 2003), pp. 8188-8196. by Ling Qi, Margaret A. Strong, Baktiar O. Karim, Mary Armanios, David L. Huso, Carol W. Greider posted to atm knockout-mouse telomere by DNAReplication on 2007-08-04 20:31:36 as along with 2 people hendryluis care100
	p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice. [My Copy] Mol Cell Biol, Vol. 23, No. 7. (April 2003), pp. 2556-2563. by I. M. Ward, K. Minn, J. van Deursen, J. Chen posted to 53bp1 g2-checkpoint knockout-mouse by DNAReplication on 2007-07-30 17:08:39 as
	The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor. [My Copy] Genes Dev, Vol. 19, No. 24. (15 December 2005), pp. 3043-3054. by M. Morales, J. W. Theunissen, C. F. Kim, R. Kitagawa, M. B. Kastan, J. H. Petrini posted to knockout-mouse rad50 by DNAReplication on 2007-07-29 20:02:43 as
	Genomic Instability in Mice Lacking Histone H2AX [My Copy] Science, Vol. 296, No. 5569. (3 May 2002), pp. 922-927. by Arkady Celeste, Simone Petersen, Peter J. Romanienko, et al.Oscar Fernandez-Capetillo, Hua T. Chen, Olga A. Sedelnikova, Bernardo Reina-San-Martin, Vincenzo Coppola, Eric Meffre, Michael J. Difilippantonio, Christophe Redon, Duane R. Pilch, Alexandru Olaru, Michael Eckhaus, Daniel R. Camerini-Otero, Lino Tessarollo, Ferenc Livak, Katia Manova, William M. Bonner, Michel C. Nussenzweig, Andre Nussenzweig posted to 53bp1 brca1 g2-checkpoint h2ax knockout-mouse by DNAReplication on 2007-07-25 21:00:18 as
	Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency. [My Copy] Mol Cell Biol, Vol. 25, No. 9. (May 2005), pp. 3535-3542. by P. L. Chen, F. Liu, S. Cai, et al.X. Lin, A. Li, Y. Chen, B. Gu, E. Y. Lee, W. H. Lee posted to ctip knockout-mouse by DNAReplication on 2007-07-12 15:07:09 as
	Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice. [My Copy] Genes Dev, Vol. 14, No. 12. (15 June 2000), pp. 1439-1447. by H. Takai, K. Tominaga, N. Motoyama, et al.Y. A. Minamishima, H. Nagahama, T. Tsukiyama, K. Ikeda, K. Nakayama, M. Nakanishi, K. Nakayama posted to chk1 knockout-mouse by DNAReplication on 2006-08-04 14:46:19 as along with 1 person catcremona
	Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription. [My Copy] EMBO J, Vol. 21, No. 19. (1 October 2002), pp. 5195-5205. by H. Takai, K. Naka, Y. Okada, et al.M. Watanabe, N. Harada, S. Saito, C. W. Anderson, E. Appella, M. Nakanishi, H. Suzuki, K. Nagashima, H. Sawa, K. Ikeda, N. Motoyama posted to chk2 g2-checkpoint knockout-mouse by DNAReplication on 2006-08-04 14:37:18 as
	Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. [My Copy] Genes Dev, Vol. 14, No. 12. (15 June 2000), pp. 1448-1459. by Q. Liu, S. Guntuku, X. S. Cui, et al.S. Matsuoka, D. Cortez, K. Tamai, G. Luo, S. Carattini-Rivera, F. DeMayo, A. Bradley, L. A. Donehower, S. J. Elledge posted to chk1 g2-checkpoint knockout-mouse by DNAReplication on 2006-08-03 12:28:42 as along with 1 person catcremona
	ATR disruption leads to chromosomal fragmentation and early embryonic lethality. [My Copy] Genes Dev, Vol. 14, No. 4. (15 February 2000), pp. 397-402. by E. J. Brown, D. Baltimore posted to atr knockout-mouse by DNAReplication on 2006-08-03 12:25:26 as along with 1 person catcremona
	Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance. [My Copy] Genes Dev, Vol. 17, No. 5. (1 March 2003), pp. 615-628. by E. J. Brown, D. Baltimore posted to atm atr knockout-mouse by DNAReplication on 2006-08-03 12:23:58 as
	An inducible null mutant murine model of Nijmegen breakage syndrome proves the essential function of NBS1 in chromosomal stability and cell viability. [My Copy] Hum Mol Genet, Vol. 13, No. 20. (15 October 2004), pp. 2385-2397. by I. Demuth, P. O. Frappart, G. Hildebrand, et al.A. Melchers, S. Lobitz, L. Stöckl, R. Varon, Z. Herceg, K. Sperling, Z. Q. Wang, M. Digweed posted to knockout-mouse nbs1 by DNAReplication on 2006-08-01 23:00:59 as

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