Tag sir2 [57 articles] Export

Recent papers classified by the tag sir2.

	Recent progress in the biology and physiology of sirtuins [My Copy] Nature, Vol. 460, No. 7255. (30 July 2009), pp. 587-591. by Toren Finkel, Chu-Xia Deng, Raul Mostoslavsky posted to sir2 by yzlab on 2009-08-03 13:22:26 as along with 4 people cmzmasek greg guhjy reyez
	Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme. [My Copy] Molecular cell, Vol. 17, No. 6. (18 March 2005), pp. 855-868. by J. L. Avalos, K. M. Bever, C. Wolberger posted to sir2 sirtuin by cannin on 2009-07-20 03:33:48 as
	Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine. [My Copy] Biochemistry, Vol. 45, No. 1. (10 January 2006), pp. 272-282. by B. C. Smith, J. M. Denu posted to sir2 by cannin on 2009-07-20 03:32:30 as
	Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. [My Copy] Genetics, Vol. 116, No. 1. (May 1987), pp. 9-22. by J. Rine, I. Herskowitz posted to sir2 by cannin on 2009-06-04 20:22:16 as
	Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state. [My Copy] Molecular cell, Vol. 12, No. 1. (July 2003), pp. 51-62. by M. Fulco, R. L. Schiltz, S. Iezzi, et al.M. T. King, P. Zhao, Y. Kashiwaya, E. Hoffman, R. L. Veech, V. Sartorelli posted to nad sir2 by cannin on 2009-05-15 18:45:39 as
	The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells. [My Copy] The Journal of biological chemistry, Vol. 279, No. 49. (3 December 2004), pp. 50754-50763. by J. R. Revollo, A. A. Grimm, S. Imai posted to nad sir2 by cannin on 2009-05-12 22:39:23 as along with 1 person Oyinlola
	The Ongoing Saga of Sirtuins and Aging [My Copy] Cell Metabolism, Vol. 8, No. 1. (2 July 2008), pp. 4-5. by Matt Kaeberlein posted to aging sir2 yeast by jdoconnell to the group Marcotte_Lab on 2009-02-28 23:35:36 as along with 1 person zhlei
	Tissue-specific regulation of SIRT1 by calorie restriction. [My Copy] Genes & development, Vol. 22, No. 13. (1 July 2008), pp. 1753-1757. by Danica Chen, Joanne Bruno, Erin Easlon, et al.Su-Ju J. Lin, Hwei-Ling L. Cheng, Frederick W. Alt, Leonard Guarente posted to aging calorie cr liver longevity restriction sir2 sirt1 by eldakak on 2008-06-16 17:02:02 as along with 2 people guhjy mkotlyar
	Sir2 Deacetylates Histone H3 Lysine 56 to Regulate Telomeric Heterochromatin Structure in Yeast [My Copy] Molecular Cell, Vol. 27, No. 6. (21 September 2007), pp. 890-900. by Feng Xu, Qiongyi Zhang, Kangling Zhang, Wei Xie, Michael Grunstein posted to heterochromatin sir2 telomere yeast by zhlei on 2008-04-28 23:06:15 as along with 2 people gderwin onufriev
	Sir2 and calorie restriction in yeast: A skeptical perspective [My Copy] Ageing Research Reviews, Vol. 6, No. 2. (August 2007), pp. 128-140. by Matt Kaeberlein, Powers posted to calorie-restriction cr sir2 yeast by zhlei on 2008-04-03 14:52:49 as
	Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. [My Copy] Nature, Vol. 423, No. 6936. (8 May 2003), pp. 181-185. by R. M. Anderson, K. J. Bitterman, J. G. Wood, O. Medvedik, D. A. Sinclair posted to lifespan sir2 sirt1 sirtuin by zhlei on 2008-02-14 03:48:23 as along with 2 people cito yedmonds
	Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction [My Copy] Genes Dev., Vol. 20, No. 21. (1 November 2006), pp. 2913-2921. by Marcia C. Haigis, Leonard P. Guarente posted to aging longevity mammal mammalian sir2 sirtuin by zhlei on 2007-09-17 21:27:14 as along with 1 person mkotlyar
	Aging, life span, and senescence [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, No. 19. (15 September 1998), pp. 11034-11036. by Leonard Guarente, Gary Ruvkun, Richard Amasino posted to aging ercs rdna sir2 yeast by zhlei on 2007-09-17 21:22:24 as along with 4 people and 1 group tjpp thegoose2 raycay3 tharris C. elegans / WormBase
	Stay Close to Your Sister [My Copy] Molecular Cell, Vol. 14, No. 4. (21 May 2004), pp. 418-420. by Robert J. Reid, Rodney Rothstein posted to erc longevity rdna sir2 yeast by zhlei on 2007-09-17 20:52:49 as
	Calorie Restriction- the SIR2 Connection. [My Copy] Cell, Vol. 120, No. 4. (25 February 2005), pp. 473-482. by L. Guarente, F. Picard posted to cr sir2 by brian on 2007-01-10 14:48:44 as along with 3 people mkotlyar yedmonds imouthesmp
	Metabolite of SIR2 reaction modulates TRPM2 ion channel. [My Copy] J Biol Chem, Vol. 281, No. 20. (19 May 2006), pp. 14057-14065. by O. Grubisha, L. A. Rafty, C. L. Takanishi, et al.X. Xu, L. Tong, A. L. Perraud, A. M. Scharenberg, J. M. Denu posted to aging apopstosis ion_channel nicotinamide signal_transduction sir2 trpm2 by imouthesmp on 2006-09-13 22:02:35 as
	Sir2-Dependent Activation of Acetyl-CoA Synthetase by Deacetylation of Active Lysine [My Copy] Science, Vol. 298, No. 5602. (20 December 2002), pp. 2390-2392. by V. J. Starai, I. Celic, R. N. Cole, J. D. Boeke, J. C. Escalante-Semerena posted to aging bacteria sir2 by johncumbers on 2006-08-11 00:47:08 as
	Poly (ADP-ribose) polymerase-1 dependent cardiac myocyte cell-death during heart failure is mediated by NAD+ depletion and reduced activity of the Sir2alpha deacetylase. [My Copy] J Biol Chem (5 October 2005) by Jyothish B B. Pillai, Ayman Isbatan, Shin-Ichiro I. Imai, Mahesh P P. Gupta posted to nad parp sir2 by yedmonds on 2005-10-10 22:14:01 as
	SIRT1 protects against microglia-dependent beta amyloid toxicity through inhibiting NF-kappa B signaling. [My Copy] J Biol Chem (23 September 2005) by Jennifer Chen, Yungui Zhou, Sarah Mueller-Steiner, et al.Lin-Feng F. Chen, Hakju Kwon, Saili Yi, Lennart Mucke, Li Gan posted to nf-kappab sir2 by yedmonds on 2005-10-03 12:52:41 as
	Calorie restriction, SIRT1 and metabolism: understanding longevity [My Copy] Nature Reviews Molecular Cell Biology, Vol. 6, No. 4. (15 March 2005), pp. 298-305. by Laura Bordone, Leonard Guarente posted to cr sir2 by yedmonds on 2005-09-06 18:40:56 as along with 3 people eehsanipour imouthesmp slevy03
	Calorie restriction and SIR2 genes--towards a mechanism. [My Copy] Mech Ageing Dev, Vol. 126, No. 9. (September 2005), pp. 923-928. by L. Guarente posted to cr sir2 by yedmonds on 2005-09-06 18:40:24 as
	Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition. [My Copy] Mol Cell, Vol. 17, No. 4. (18 February 2005), pp. 595-601. by A. A. Sauve, R. D. Moir, V. L. Schramm, I. M. Willis posted to nicotinamide npt1 sir2 by yedmonds on 2005-07-12 17:55:44 as
	Coenzyme specificity of Sir2 protein deacetylases: implications for physiological regulation. [My Copy] J Biol Chem, Vol. 279, No. 38. (17 September 2004), pp. 40122-40129. by M. T. Schmidt, B. C. Smith, M. D. Jackson, J. M. Denu posted to nicotinamide sir2 by yedmonds on 2005-06-29 20:34:51 as
	Molecular links between aging and adipose tissue. [My Copy] Int J Obes Relat Metab Disord, Vol. 29 Suppl 1 (March 2005) by F. Picard, L. Guarente posted to adipocytes ageing sir2 by yedmonds on 2005-06-22 20:47:18 as along with 1 person and 4 groups HEIRS HEIRS Obesity and Lipid Regulation HEIRS LIfespan and Ageing HEIRS - Environmental Illness Research HEIRS Cellular Biology
	Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation. [My Copy] Cell, Vol. 121, No. 4. (20 May 2005), pp. 515-527. by G. G. Liou, J. C. Tanny, R. G. Kruger, T. Walz, D. Moazed posted to chromatinremodeling oacetyladpr silencing sir2 by yedmonds on 2005-06-22 17:32:26 as
	Role of NAD(+) in the deacetylase activity of the SIR2-like proteins. [My Copy] Biochem Biophys Res Commun, Vol. 278, No. 3. (30 November 2000), pp. 685-690. by J. Landry, J. T. Slama, R. Sternglanz posted to methods nadnadh sir2 by yedmonds on 2005-06-22 17:22:09 as
	Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. [My Copy] Biochem Biophys Res Commun, Vol. 273, No. 2. (5 July 2000), pp. 793-798. by R. A. Frye posted to sir2 by yedmonds on 2005-06-22 17:19:50 as along with 1 person cannin
	Ordered nucleation and spreading of silenced chromatin in Saccharomyces cerevisiae. [My Copy] Mol Biol Cell, Vol. 13, No. 7. (July 2002), pp. 2207-2222. by L. N. Rusché, A. L. Kirchmaier, J. Rine posted to chromatinremodeling silencing sir2 by yedmonds on 2005-06-22 17:18:30 as
	The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae. [My Copy] Annu Rev Biochem, Vol. 72 (2003), pp. 481-516. by L. N. Rusche, A. L. Kirchmaier, J. Rine posted to chromatinremodeling silencing sir2 by yedmonds on 2005-06-22 17:17:46 as
	Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry. [My Copy] Biochemistry, Vol. 42, No. 31. (12 August 2003), pp. 9249-9256. by A. A. Sauve, V. L. Schramm posted to nicotinamide sir2 by yedmonds on 2005-06-22 16:58:54 as
	Are poly(ADP-ribosyl)ation by PARP-1 and deacetylation by Sir2 linked? [My Copy] Bioessays, Vol. 25, No. 8. (August 2003), pp. 808-814. by J. Zhang posted to nadnadh nicotinamide par parp sir2 by yedmonds on 2005-06-22 15:06:36 as
	Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. [My Copy] Biochem Biophys Res Commun, Vol. 260, No. 1. (24 June 1999), pp. 273-279. by R. A. Frye posted to sir2 by yedmonds on 2005-06-22 14:56:25 as along with 1 person slevy03
	An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing. [My Copy] Cell, Vol. 99, No. 7. (23 December 1999), pp. 735-745. by J. C. Tanny, G. J. Dowd, J. Huang, H. Hilz, D. Moazed posted to silencing sir2 by yedmonds on 2005-06-22 14:55:18 as
	Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose. [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, No. 26. (19 December 2000), pp. 14178-14182. by K. G. Tanner, J. Landry, R. Sternglanz, J. M. Denu posted to nadnadh oacetyladpr sir2 by yedmonds on 2005-06-22 14:52:32 as along with 1 person cannin
	Navigating novel mechanisms of cellular plasticity with the NAD+ precursor and nutrient nicotinamide. [My Copy] Front Biosci, Vol. 9 (1 September 2004), pp. 2500-2520. by F. Li, Z. Z. Chong, K. Maiese posted to ageing nadnadh nicotinamide parp sir2 by yedmonds on 2005-06-22 14:25:40 as
	The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. [My Copy] J Cell Biol, Vol. 158, No. 4. (19 August 2002), pp. 647-657. by B. Schwer, B. J. North, R. A. Frye, M. Ott, E. Verdin posted to mitochondria nadnadh sir2 by yedmonds on 2005-06-22 14:20:23 as
	Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta -NAD+-dependent histone/protein deacetylases. [My Copy] J Biol Chem, Vol. 277, No. 21. (24 May 2002), pp. 18535-18544. by M. D. Jackson, J. M. Denu posted to nadnadh oacetyladpr sir2 by yedmonds on 2005-06-22 14:17:41 as
	Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions. [My Copy] Biochemistry, Vol. 40, No. 51. (25 December 2001), pp. 15456-15463. by A. A. Sauve, I. Celic, J. Avalos, H. Deng, J. D. Boeke, V. L. Schramm posted to nadnadh sir2 by yedmonds on 2005-06-22 14:15:29 as
	Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product. [My Copy] Proc Natl Acad Sci U S A, Vol. 98, No. 2. (16 January 2001), pp. 415-420. by J. C. Tanny, D. Moazed posted to histones nadnadh sir2 by yedmonds on 2005-06-22 14:13:52 as
	Enzymology of NAD+ homeostasis in man. [My Copy] Cell Mol Life Sci, Vol. 61, No. 1. (January 2004), pp. 19-34. by G. Magni, A. Amici, M. Emanuelli, G. Orsomando, N. Raffaelli, S. Ruggieri posted to nadnadh nicotinamide parp sir2 by yedmonds on 2005-06-22 13:58:08 as
	Substrate-specific activation of sirtuins by resveratrol. [My Copy] J Biol Chem, Vol. 280, No. 17. (29 April 2005), pp. 17038-17045. by M. Kaeberlein, T. McDonagh, B. Heltweg, et al.J. Hixon, E. A. Westman, S. D. Caldwell, A. Napper, R. Curtis, P. S. DiStefano, S. Fields, A. Bedalov, B. K. Kennedy posted to resveratrol sir2 by yedmonds on 2005-06-22 13:51:42 as
	Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. [My Copy] Nature, Vol. 425, No. 6954. (11 September 2003), pp. 191-196. by K. T. Howitz, K. J. Bitterman, H. Y. Cohen, et al.D. W. Lamming, S. Lavu, J. G. Wood, R. E. Zipkin, P. Chung, A. Kisielewski, L. L. Zhang, B. Scherer, D. A. Sinclair posted to ageing resveratrol sir2 by yedmonds on 2005-06-22 13:49:19 as along with 1 person zhlei
	Mechanism of human SIRT1 activation by resveratrol. [My Copy] J Biol Chem, Vol. 280, No. 17. (29 April 2005), pp. 17187-17195. by M. T. Borra, B. C. Smith, J. M. Denu posted to resveratrol sir2 by yedmonds on 2005-06-22 13:45:45 as
	Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases. [My Copy] J Biol Chem, Vol. 277, No. 15. (12 April 2002), pp. 12632-12641. by M. T. Borra, F. J. O'Neill, M. D. Jackson, et al.B. Marshall, E. Verdin, K. R. Foltz, J. M. Denu posted to nadnadh oacetyladpr sir2 by yedmonds on 2005-06-22 13:44:06 as
	Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases. [My Copy] Trends Biochem Sci, Vol. 28, No. 1. (January 2003), pp. 41-48. by J. M. Denu posted to chromatinremodeling nadnadh sir2 by yedmonds on 2005-06-20 21:24:40 as
	The new life of a centenarian: signalling functions of NAD(P). [My Copy] Trends Biochem Sci, Vol. 29, No. 3. (March 2004), pp. 111-118. by F. Berger, M. H. Ramírez-Hernández, M. Ziegler posted to ageing nadnadh nicotinamide oacetyladpr parp sir2 by yedmonds on 2005-06-20 21:20:02 as
	Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. [My Copy] J Biol Chem, Vol. 277, No. 47. (22 November 2002), pp. 45099-45107. by K. J. Bitterman, R. M. Anderson, H. Y. Cohen, M. Latorre-Esteves, D. A. Sinclair posted to ageing nicotinamide silencing sir2 by yedmonds on 2005-06-20 21:03:50 as
	Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. [My Copy] Nature, Vol. 418, No. 6895. (18 July 2002), pp. 344-348. by S. J. Lin, M. Kaeberlein, A. A. Andalis, et al.L. A. Sturtz, P. A. Defossez, V. C. Culotta, G. R. Fink, L. Guarente posted to ageing cr sir2 by yedmonds on 2005-06-20 21:02:52 as along with 2 people mkotlyar lesander
	Negative control of p53 by Sir2alpha promotes cell survival under stress. [My Copy] Cell, Vol. 107, No. 2. (19 October 2001), pp. 137-148. by J. Luo, A. Y. Nikolaev, S. Imai, et al.D. Chen, F. Su, A. Shiloh, L. Guarente, W. Gu posted to ageing p53 sir2 by yedmonds on 2005-06-20 21:02:09 as
	hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. [My Copy] Cell, Vol. 107, No. 2. (19 October 2001), pp. 149-159. by H. Vaziri, S. K. Dessain, E. Ng Eaton, et al.S. I. Imai, R. A. Frye, T. K. Pandita, L. Guarente, R. A. Weinberg posted to p53 sir2 by yedmonds on 2005-06-20 21:01:20 as

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nadnadh	16
ageing	13
cr	9
nicotinamide	9
aging	7
silencing	6
yeast	6
oacetyladpr	5
parp	5
chromatinremodeling	4
longevity	3
nad	3
resveratrol	3
sirtuin	3
histones	2
p53	2
rdna	2
sirt1	2
adipocytes	1
apopstosis	1
bacteria	1
calorie	1
calorie-restriction	1
erc	1
ercs	1
heterochromatin	1
ion_channel	1
lifespan	1
liver	1
mammal	1
mammalian	1
methods	1
mitochondria	1
nf-kappab	1
npt1	1
par	1
restriction	1
signal_transduction	1
telomere	1
trpm2	1

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