Tag skp2 [48 articles] Export

Recent papers classified by the tag skp2.

	Phosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APCCdh1 in G1 phase [My Copy] The EMBO Journal, Vol. aop, No. current. (31 January 2008) by Genevieve Rodier, Philippe Coulombe, Pierre-Luc Tanguay, Christel Boutonnet, Sylvain Meloche posted to apc skp2 by guhjy on 2009-04-05 13:34:22 as
	Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells. [My Copy] The Journal of clinical investigation, Vol. 117, No. 10. (October 2007), pp. 2869-2876. by L. Zhong, S. Georgia, S. I. Tschen, K. Nakayama, K. Nakayama, A. Bhushan posted to dm skp2 p27 by guhjy on 2009-04-05 12:55:54 as
	Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer [My Copy] Nature Reviews Cancer, Vol. 8, No. 6., pp. 438-449. by David Frescas, Michele Pagano posted to cancer skp2 by guhjy on 2009-04-05 12:53:54 as
	Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer. [My Copy] Cancer, Vol. 112, No. 7. (1 April 2008), pp. 1415-1424. by D. D. Hershko posted to cancer skp2 by guhjy on 2009-04-05 12:53:44 as
	A reciprocal relationship between Rb and Skp2: implications for restriction point control, signal transduction to the cell cycle and cancer. [My Copy] Cell cycle (Georgetown, Tex.), Vol. 7, No. 1. (January 2008), pp. 24-27. by R. K. Assoian, Y. Yung posted to cancer rb skp2 by guhjy on 2009-04-05 12:53:17 as along with 1 person catcremona
	Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB [My Copy] Nature Cell Biology, Vol. 11, No. 4. (08 March 2009), pp. 420-432. by Hui-Kuan Lin, Guocan Wang, Zhenbang Chen, et al.Julie Teruya-Feldstein, Yan Liu, Chia-Hsin Chan, Wei-Lei Yang, Hediye Erdjument-Bromage, Keiichi I. Nakayama, Stephen Nimer, Paul Tempst, Pier P. Pandolfi posted to skp2 akt by guhjy on 2009-04-05 12:51:52 as along with 2 people bloomekj renatomilani
	Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction [My Copy] Nature Cell Biology, Vol. 11, No. 4. (08 March 2009), pp. 397-408. by Daming Gao, Hiroyuki Inuzuka, Alan Tseng, Rebecca Y. Chin, Alex Toker, Wenyi Wei posted to phosphorylation akt skp2 by guhjy on 2009-04-05 12:51:45 as along with 1 person renatomilani
	Skp2: caught in the Akt [My Copy] Nature Cell Biology, Vol. 11, No. 4., pp. 377-379. by Karin Ecker, Ludger Hengst posted to akt skp2 by guhjy on 2009-04-05 12:50:28 as
	Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis [My Copy] The EMBO Journal, Vol. aop, No. current. (16 February 2006) by Hideo Nishitani, Nozomi Sugimoto, Vassilis Roukos, et al.Yohsuke Nakanishi, Masafumi Saijo, Chikashi Obuse, Toshiki Tsurimoto, Keiichi I. Nakayama, Keiko Nakayama, Masatoshi Fujita, Zoi Lygerou, Takeharu Nishimoto posted to cdt1 cul4 degradation skp2 by catcremona on 2009-02-06 00:55:50 as along with 1 person DNAReplication
	Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex. [My Copy] Nature, Vol. 428, No. 6979. (11 March 2004), pp. 194-198. by W. Wei, N. G. Ayad, Y. Wan, G. J. Zhang, M. W. Kirschner, W. G. Kaelin posted to apc degradation scf skp2 by catcremona on 2009-02-01 05:16:59 as
	Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase. [My Copy] The Journal of biological chemistry, Vol. 278, No. 28. (11 July 2003), pp. 25752-25757. by G. Bornstein, J. Bloom, D. Sitry-Shevah, K. Nakayama, M. Pagano, A. Hershko posted to degradation p21 scf skp2 ubiquitin by catcremona on 2009-01-04 14:05:48 as
	BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells. [My Copy] Cancer research, Vol. 65, No. 8. (15 April 2005), pp. 3264-3272. by E. J. Andreu, E. Lledó, E. Poch, et al.C. Ivorra, M. P. Albero, J. A. Martínez-Climent, C. Montiel-Duarte, J. Rifón, J. Pérez-Calvo, C. Arbona, F. Prósper, I. Pérez-Roger posted to degradation leukaemia p27 skp2 by catcremona on 2008-10-03 17:23:10 as
	The combination of high cyclin E and Skp2 expression in breast cancer is associated with a poor prognosis and the basal phenotype [My Copy] Human Pathology, Vol. 39, No. 10. (October 2008), pp. 1431-1437. by David Voduc, Torsten O. Nielsen, Maggie C. Cheang, William D. Foulkes posted to basal breast cancer cyclin-e journal-club pathways phenotype skp2 by Zephyrus to the group Breast Cancer Reading Club on 2008-10-03 03:04:28 as
	Inverse relationship between Skp2 ubiquitin ligase and the cyclin dependent kinase inhibitor p27Kip1 in prostate cancer. [My Copy] The Journal of urology, Vol. 170, No. 1. (July 2003), pp. 241-245. by O. Ben-Izhak, S. Lahav-Baratz, S. Meretyk, et al.S. Ben-Eliezer, E. Sabo, M. Dirnfeld, S. Cohen, A. Ciechanover posted to cancer p27 prostate skp2 by catcremona on 2008-09-22 11:26:33 as
	Impaired germ cell development due to compromised cell cycle progression in Skp2-deficient mice [My Copy] Cell Division, Vol. 1 (07 April 2006), 4. by Abbas Fotovati, Keiko Nakayama, Keiichi I. Nakayama posted to aneuploidy p27 polyploidy skp2 by catcremona on 2008-09-09 17:19:56 as
	Skp2 Overexpression Is a Prognostic Factor in Patients with Ovarian Adenocarcinoma [My Copy] Clin Cancer Res, Vol. 9, No. 5. (1 May 2003), pp. 1756-1763. by Kazushi Shigemasa, Lijun Gu, Timothy J. O'Brien, Koso Ohama posted to cancer ovarian skp2 by catcremona on 2008-07-22 14:03:52 as
	Correlation of Skp2 with carcinogenesis, invasion, metastasis, and prognosis in colorectal tumors. [My Copy] International journal of oncology, Vol. 25, No. 1. (July 2004), pp. 87-95. by J. Q. Li, F. Wu, T. Masaki, et al.A. Kubo, J. Fujita, D. A. Dixon, R. D. Beauchamp, T. Ishida, S. Kuriyama, K. Imaida posted to cancer colorectal skp2 by catcremona on 2008-07-22 13:29:48 as
	Skp2 and Jab1 expression are associated with inverse expression of p27(KIP1) and poor prognosis in oral squamous cell carcinomas. [My Copy] Oncology, Vol. 65, No. 4. (2003), pp. 355-362. by S. Shintani, C. Li, M. Mihara, S. Hino, K. Nakashiro, H. Hamakawa posted to cancer oral p27 skp2 by catcremona on 2008-07-22 13:27:00 as
	High Expression of S-Phase Kinase-interacting Protein 2, Human F-box Protein, Correlates with Poor Prognosis in Oral Squamous Cell Carcinomas [My Copy] Cancer Res, Vol. 61, No. 19. (1 October 2001), pp. 7044-7047. by Yasusei Kudo, Shojiro Kitajima, Sunao Sato, Mutsumi Miyauchi, Ikuko Ogawa, Takashi Takata posted to cancer oral skp2 by catcremona on 2008-07-22 13:25:48 as
	Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer. [My Copy] J Clin Invest, Vol. 110, No. 5. (September 2002), pp. 633-641. by S. Signoretti, L. Di Marcotullio, A. Richardson, et al.S. Ramaswamy, B. Isaac, M. Rue, F. Monti, M. Loda, M. Pagano posted to breast cancer skp2 by catcremona on 2008-07-22 12:43:41 as along with 1 person jfr
	Elevated Skp2 Protein Expression in Human Prostate Cancer: Association with Loss of the Cyclin-dependent Kinase Inhibitor p27 and PTEN and with Reduced Recurrence-free Survival [My Copy] Clin Cancer Res, Vol. 8, No. 11. (1 November 2002), pp. 3419-3426. by Guang Yang, Gustavo Ayala, Angelo D. Marzo, et al.Weihua Tian, Anna Frolov, Thomas M. Wheeler, Timothy C. Thompson, Wade J. Harper posted to cancer p27 prostate pten skp2 by catcremona on 2008-07-22 12:40:27 as
	Skp2 Overexpression Is Highly Representative of Intrinsic Biological Aggressiveness and Independently Associated with Poor Prognosis in Primary Localized Myxofibrosarcomas [My Copy] Clin Cancer Res, Vol. 12, No. 2. (15 January 2006), pp. 487-498. by Hsuan-Ying Huang, Hong-Yo Kang, Chien-Feng Li, et al.Hock-Liew Eng, Shih-Cheng Chou, Ching-Nan Lin, Ching-Yeh Hsiung posted to cancer skp2 by catcremona on 2008-07-22 00:08:56 as
	p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells. [My Copy] Nature cell biology, Vol. 1, No. 4. (August 1999), pp. 207-214. by H. Sutterlüty, E. Chatelain, A. Marti, et al.C. Wirbelauer, M. Senften, U. Müller, W. Krek posted to degradation p27 skp2 sphase by catcremona on 2008-07-21 22:24:54 as
	p27 destruction: Cks1 pulls the trigger [My Copy] Nat Cell Biol, Vol. 3, No. 4. (April 2001), pp. E95-E97. by Jiri Bartek, Jiri Lukas posted to cks1 degradation p27 skp2 by catcremona on 2008-07-21 20:32:19 as
	SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. [My Copy] Nature cell biology, Vol. 1, No. 4. (August 1999), pp. 193-199. by A. C. Carrano, E. Eytan, A. Hershko, M. Pagano posted to degradation p27 skp2 ubiquitin by catcremona on 2008-07-18 19:31:09 as
	Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression. [My Copy] The Journal of cell biology, Vol. 153, No. 7. (25 June 2001), pp. 1381-1390. by A. C. Carrano, M. Pagano posted to adhesion cellcycle degradation p27 skp2 by catcremona on 2008-07-14 15:20:26 as
	A Skp2 autoinduction loop and restriction point control. [My Copy] The Journal of cell biology, Vol. 178, No. 5. (27 August 2007), pp. 741-747. by Y. Yung, J. L. Walker, J. M. Roberts, R. K. Assoian posted to cell cycle feedback loop rb skp2 by catcremona on 2008-05-27 21:18:42 as
	Skp2-mediated degradation of p27 regulates progression into mitosis. [My Copy] Developmental cell, Vol. 6, No. 5. (May 2004), pp. 661-672. by K. Nakayama, H. Nagahama, Y. A. Minamishima, et al.S. Miyake, N. Ishida, S. Hatakeyama, M. Kitagawa, S. Iemura, T. Natsume, K. I. Nakayama posted to degradation mitosis p27 skp2 by catcremona on 2008-05-27 19:29:40 as
	Ubiquitin ligases in malignant lymphoma. [My Copy] Leuk Lymphoma, Vol. 45, No. 7. (July 2004), pp. 1329-1339. by M. S. Lim, K. S. Elenitoba-Johnson posted to cancer degradation lymphoma skp2 ubiquitination by tibbitts on 2008-03-23 19:36:16 as
	Skp2 contains a novel cyclin A binding domain that directly protects cyclin A from inhibition by p27Kip1. [My Copy] J Biol Chem, Vol. 281, No. 33. (18 August 2006), pp. 24058-24069. by P. Ji, L. Goldin, H. Ren, et al.D. Sun, D. Guardavaccaro, M. Pagano, L. Zhu posted to cyclina p27 skp2 by catcremona on 2008-03-18 17:34:58 as
	Skp2-Mediated Degradation of p27 Regulates Progression into Mitosis [My Copy] Developmental Cell, Vol. 6, No. 5. (May 2004), pp. 661-672. by Keiko Nakayama, Hiroyasu Nagahama, Yohji A. Minamishima, et al.Satoshi Miyake, Noriko Ishida, Shigetsugu Hatakeyama, Masatoshi Kitagawa, Shun-Ichiro Iemura, Tohru Natsume, Keiichi I. Nakayama posted to degradation mitosis p27 skp2 by catcremona on 2008-01-04 12:24:33 as
	Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication. [My Copy] EMBO J, Vol. 19, No. 9. (2 May 2000), pp. 2069-2081. by K. Nakayama, H. Nagahama, Y. A. Minamishima, et al.M. Matsumoto, I. Nakamichi, K. Kitagawa, M. Shirane, R. Tsunematsu, T. Tsukiyama, N. Ishida, M. Kitagawa, K. Nakayama, S. Hatakeyama posted to centrosome chromosome cycline duplication p27 polyploidy skp2 by catcremona on 2007-12-21 14:49:17 as
	CD28 costimulation mediates transcription of SKP2 and CKS1, the substrate recognition components of SCFSkp2 ubiquitin ligase that leads p27kip1 to degradation. [My Copy] Cell Cycle, Vol. 5, No. 18. (September 2006), pp. 2123-2129. by L. J. Appleman, I. Chernova, L. Li, V. A. Boussiotis posted to cd28 cks1 degradation lymphocytes p27 skp2 ubiquitin by catcremona on 2007-12-21 14:46:52 as
	Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells [My Copy] Oncogene, Vol. aop, No. current. by K. V. Bhatt, R. Hu, L. S. Spofford, A. E. Aplin posted to cyclind melanoma p27 raf skp2 by catcremona on 2007-12-21 14:43:24 as
	Focal adhesion kinase controls cellular levels of p27/Kip1 and p21/Cip1 through Skp2-dependent and -independent mechanisms. [My Copy] Mol Cell Biol, Vol. 26, No. 11. (June 2006), pp. 4201-4213. by P. Bryant, Q. Zheng, K. Pumiglia posted to fak p21 p27 skp2 by catcremona on 2007-12-21 14:41:17 as
	Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway. [My Copy] J Biol Chem, Vol. 276, No. 52. (28 December 2001), pp. 48937-48943. by T. Hara, T. Kamura, K. Nakayama, K. Oshikawa, S. Hatakeyama, K. Nakayama posted to degradation g0 g1 p27 skp2 ubiquitination by catcremona on 2007-12-20 18:14:36 as along with 1 person guhjy
	MM-1 facilitates degradation of c-Myc by recruiting proteasome and a novel ubiquitin E3 ligase. [My Copy] Int J Oncol, Vol. 31, No. 4. (October 2007), pp. 829-836. by Y. Kimura, A. Nagao, Y. Fujioka, et al.A. Satou, T. Taira, S. M. Iguchi-Ariga, H. Ariga posted to degradation myc skp2 ubiquitination by tibbitts on 2007-10-16 05:45:41 as
	Down-regulation of p27Kip1 Promotes Cell Proliferation of Rat Neonatal Cardiomyocytes Induced by Nuclear Expression of Cyclin D1 and CDK4: EVIDENCE FOR IMPAIRED Skp2-DEPENDENT DEGRADATION OF p27 IN TERMINAL DIFFERENTIATION [My Copy] J. Biol. Chem., Vol. 279, No. 48. (26 November 2004), pp. 50429-50436. by Mimi Tamamori-Adachi, Kentaro Hayashida, Kiyoshi Nobori, et al.Chie Omizu, Kazuhiko Yamada, Naoya Sakamoto, Takumi Kamura, Keiichi Fukuda, Satoshi Ogawa, Keiichi I. Nakayama, Shigetaka Kitajima posted to cdk2 cdk4 cyclind p27 sirna skp2 by catcremona on 2007-10-05 15:10:05 as
	p27(Kip1) stabilization and G(1) arrest by 1,25-dihydroxyvitamin D(3) in ovarian cancer cells mediated through down-regulation of cyclin E/cyclin-dependent kinase 2 and Skp1-Cullin-F-box protein/Skp2 ubiquitin ligase. [My Copy] J Biol Chem, Vol. 279, No. 24. (11 June 2004), pp. 25260-25267. by P. Li, C. Li, X. Zhao, X. Zhang, S. V. Nicosia, W. Bai posted to arrest cdk2 cycline p27 skp1 skp2 vitamind3 by catcremona on 2007-10-05 14:50:26 as
	Skp2 regulates Myc protein stability and activity. [My Copy] Mol Cell, Vol. 11, No. 5. (May 2003), pp. 1177-1188. by S. Y. Kim, A. Herbst, K. A. Tworkowski, S. E. Salghetti, W. P. Tansey posted to degradation myc skp2 ubiquitination by tibbitts on 2007-08-27 09:55:59 as
	The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription. [My Copy] Mol Cell, Vol. 11, No. 5. (May 2003), pp. 1189-1200. by N. von der Lehr, S. Johansson, S. Wu, et al.F. Bahram, A. Castell, C. Cetinkaya, P. Hydbring, I. Weidung, K. Nakayama, K. I. Nakayama, O. Söderberg, T. K. Kerppola, L. G. Larsson posted to degradation myc skp2 transcription by tibbitts on 2007-08-27 09:50:31 as
	Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition. [My Copy] J Biol Chem, Vol. 279, No. 25. (18 June 2004), pp. 26323-26330. by A. Mammoto, S. Huang, K. Moore, P. Oh, D. E. Ingber posted to g1s mdia p27 rho rock shape skp2 by catcremona on 2006-08-14 14:23:00 as
	Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase. [My Copy] J Biol Chem, Vol. 280, No. 24. (17 June 2005), pp. 23416-23423. by D. Y. Takeda, J. D. Parvin, A. Dutta posted to cdt1 cul4 skp2 by DNAReplication on 2006-08-09 21:17:00 as along with 1 person sansamcl
	Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation. [My Copy] J Biol Chem, Vol. 279, No. 17. (23 April 2004), pp. 17283-17288. by E. Liu, X. Li, F. Yan, Q. Zhao, X. Wu posted to cdt1 skp2 by DNAReplication on 2006-08-09 21:11:45 as along with 2 people catcremona sansamcl
	The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation. [My Copy] J Biol Chem, Vol. 278, No. 33. (15 August 2003), pp. 30854-30858. by X. Li, Q. Zhao, R. Liao, P. Sun, X. Wu posted to cdt1 scf skp2 by DNAReplication on 2006-08-09 19:04:05 as along with 1 person sansamcl
	Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosome. [My Copy] Mol Cell Biol, Vol. 26, No. 7. (April 2006), pp. 2531-2539. by T. Bondar, A. Kalinina, L. Khair, et al.D. Kopanja, A. Nag, S. Bagchi, P. Raychaudhuri posted to cul4 ddb1 p27 skp2 by DNAReplication on 2006-07-27 14:23:37 as
	Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding. [My Copy] J Biol Chem, Vol. 279, No. 19. (7 May 2004), pp. 19691-19697. by N. Sugimoto, Y. Tatsumi, T. Tsurumi, et al.A. Matsukage, T. Kiyono, H. Nishitani, M. Fujita posted to cdt1 cyclina geminin scf skp2 by DNAReplication on 2006-07-19 23:13:36 as along with 1 person catcremona
	Focal adhesion kinase (FAK)-dependent regulation of S-phase kinase-associated protein-2 (Skp-2) stability. A novel mechanism regulating smooth muscle cell proliferation. [My Copy] J Biol Chem, Vol. 279, No. 36. (3 September 2004), pp. 37304-37310. by M. Bond, G. B. Sala-Newby, A. C. Newby posted to fak muscle p27 skp2 by catcremona on 2005-11-22 17:36:25 as

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p27	23
degradation	16
cancer	15
cdt1	6
scf	5
cul4	4
ubiquitination	4
akt	3
breast	3
myc	3
rb	3
ubiquitin	3
apc	2
basal	2
cdk2	2
cell	2
cks1	2
cycle	2
cyclin-e	2
cyclina	2
cyclind	2
cycline	2
ddb1	2
fak	2
feedback	2
journal-club	2
loop	2
mitosis	2
oral	2
p21	2
phenotype	2
polyploidy	2
prostate	2
adhesion	1
aneuploidy	1
arrest	1
cd28	1
cdk4	1
cellcycle	1
centrosome	1
chromosome	1
colorectal	1
dm	1
duplication	1
g0	1
g1	1
g1s	1
geminin	1
leukaemia	1
lymphocytes	1
lymphoma	1
mdia	1
melanoma	1
muscle	1
ovarian	1
pathway	1
pathways	1
phosphorylation	1
pten	1
raf	1
rho	1
rock	1
shape	1
sirna	1
skp1	1
sphase	1
thelist	1
transcription	1
vitamind3	1

Tag skp2 [48 articles] Export

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