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Tag toxicology [111 articles]

Recent papers classified by the tag toxicology.
  • Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs.
    J Clin Pharmacol, Vol. 47, No. 5. (May 2007), pp. 566-578.
    by BL Urquhart, RG Tirona, RB Kim
    posted to drugs hnf4 toxicology by yevishere on 2008-01-03 23:18:50 as **
  • Nuclear receptor-mediated transcriptional regulation in Phase I, II, and III xenobiotic metabolizing systems.
    Drug Metab Pharmacokinet, Vol. 21, No. 6. (December 2006), pp. 437-457.
    by K Nakata, Y Tanaka, T Nakano, T Adachi, H Tanaka, T Kaminuma, T Ishikawa
    posted to hnf4 review toxicology by yevishere on 2008-01-03 23:41:18 as **
  • Differentiation of neonatal rat epithelial cells from biliary origin into immature hepatic cells by sequential exposure to hepatogenic cytokines and growth factors reflecting liver development.
    Toxicol In Vitro, Vol. 21, No. 7. (October 2007), pp. 1325-1331.
    by S Snykers, J De Kock, T Vanhaecke, V Rogiers
    posted to hnf4 targets toxicology by yevishere on 2008-01-03 23:15:20 as **
  • Comments to 'can we reverse the burden of proof?'.
    Toxicol Lett, Vol. 90, No. 2-3. (7 February 1997), pp. 233-234.
    by P Gelbke
    posted to burden_of_proof toxicology by wandall on 2007-02-18 08:12:22 as **
  • Comments to 'Can we reverse the burden of proof?'.
    Toxicol Lett, Vol. 90, No. 2-3. (7 February 1997), pp. 229-232.
    by IF Purchase
    posted to burden_of_proof toxicology by wandall on 2007-02-18 08:12:54 as **
  • Food supplements and European regulation within a precautionary context: a critique and implications for nutritional, toxicological and regulatory consistency.
    Crit Rev Food Sci Nutr, Vol. 47, No. 3. (2007), pp. 267-285.
    by JC Hanekamp, A Bast
    posted to false_positivefalse_negative precaution regulation toxicology value by wandall on 2007-07-11 13:59:08 as **
  • Regulatory toxicology: objectives and tasks defined by the working group of the German society of experimental and clinical pharmacology and toxicology.
    Toxicol Lett, Vol. 126, No. 3. (7 February 2002), pp. 145-153.
    by M Schwenk, M Werner, M Younes
    posted to regulation toxicology by wandall on 2007-02-18 08:17:29 as **
  • Resolving disputes about toxicological risks during military conflict : the US Gulf War experience.
    Toxicol Rev, Vol. 24, No. 3. (2005), pp. 167-180.
    by KC Hyams, M Brown, DS White
    posted to controversy risk toxicology by wandall on 2007-07-11 14:26:59 as **
  • The occupational toxicologist: professionalism, morality and ethical standards in the context of legal and non-litigation issues.
    J Appl Toxicol, Vol. 25, No. 6. (c 2005), pp. 496-513.
    by B Ballantyne
    posted to toxicology by wandall on 2007-02-18 08:14:30 as **
  • The role of toxicological science in risk assessment and risk management.
    Adv Exp Med Biol, Vol. 500 (2001), pp. 651-656.
    by BD Goldstein
    posted to risk_assessment risk_management science toxicology by wandall on 2007-01-07 14:39:47 as **
  • Threshold values in toxicology - useful or not?
    Forensic Sci Int, Vol. 113, No. 1-3. (11 September 2000), pp. 323-330.
    by R Wennig
    posted to threshold toxicology by wandall on 2007-02-18 08:18:19 as **
  • Regulatory toxicology: objectives and tasks defined by the working group of the German society of experimental and clinical pharmacology and toxicology
    Toxicology Letters, Vol. 126, No. 3. (7 February 2002), pp. 161-162.
    by D Mayer
    posted to toxicology by wandall on 2007-02-18 08:19:58 as **
  • Mechanism-based toxicology in cancer risk assessment: implications for research, regulation, and legislation.
    Environ Health Perspect, Vol. 104, No. 1. (January 1996), pp. 84-88.
    by GW Lucier
    posted to carcinogen mechanism risk_assessment toxicology by wandall on 2007-02-18 08:15:28 as **
  • Can we reverse the burden of proof?
    Toxicol Lett, Vol. 90, No. 2-3. (7 February 1997), pp. 223-228.
    by SO Hansson
    posted to burden_of_proof toxicology by wandall on 2007-02-17 12:02:32 as read
  • Does dioxin exert toxic effects in humans at or near current background body levels?: an evidence-based conclusion
    pp. 99-105.
    by P Guzelian
    posted to conservative dioxine ebt risk_assessment toxicology by wandall on 2006-11-09 19:13:15 as read
  • Regulatory toxicology: objectives and tasks defined by the working group of the German society of experimental and clinical pharmacology and toxicology.
    Toxicol Lett, Vol. 126, No. 3. (7 February 2002), pp. 159-160.
    by HP Gelbke
    posted to toxicology by wandall on 2007-02-18 08:13:39 as **
  • Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure.
    Endocrinology, Vol. 147, No. 6 Suppl. (June 2006)
    by WV Welshons, SC Nagel, FS vom Saal
    posted to toxicology by wandall on 2007-05-01 09:54:29 as **
  • Bias in toxicology.
    Arch Toxicol, Vol. 81, No. 9. (September 2007), pp. 605-617.
    by B Wandall, SO Hansson, C Rudén
    posted to bias toxicology by wandall on 2007-08-08 13:49:43 as read
  • A survey of discriminant methods used in toxicological histopathology.
    Toxicol Pathol, Vol. 29, No. 2. (r 2001), pp. 269-273.
    by T Holland
    posted to blinding histopathology scientific_method toxicology by wandall on 2006-11-09 20:18:06 as read
  • Evidence-based toxicology: a comprehensive framework for causation
    pp. 161-201.
    by Philip S Guzelian
    posted to ebt evidence-based toxicology by wandall on 2006-11-09 19:10:46 as read
  • Can hormesis be a default for dose-response?
    Hum Exp Toxicol, Vol. 24, No. 5. (May 2005), pp. 271-273.
    by BG Callahan
    posted to dose-response hormesis toxicology by wandall on 2007-03-17 10:50:20 as **
  • The need for a new toxicity testing and risk analysis paradigm to implement REACH or any other large scale testing initiative
    Archives of Toxicology
    by Bas J Blaauboer, Melvin E Andersen
    posted to animal_studies reach risk_assessment toxicology by wandall on 2007-02-15 15:22:48 as **
  • Toxicology rethinks its central belief.
    Nature, Vol. 421, No. 6924. (13 February 2003), pp. 691-692.
    by EJ Calabrese, LA Baldwin
    posted to hormesis toxicology by wandall on 2007-02-18 08:16:33 as **
  • Regulatory toxicology: objectives and tasks defined by the working group of the German society of experimental and clinical pharmacology and toxicology
    Toxicology Letters, Vol. 126, No. 3. (7 February 2002), pp. 163-165.
    by Iain F Purchase
    posted to toxicology by wandall on 2007-02-18 08:19:13 as **
  • Statistical Issues in Toxicology
    Journal of the American Statistical Association, Vol. 95, No. 449. (2000), pp. 304-308.
    by Louise M Ryan
    posted to statistics toxicology by wandall on 2006-11-09 19:52:09 as read
  • Toxicological comments to the discussion about REACH
    Archives of Toxicology, Vol. V80, No. 3. (1 March 2006), pp. 121-124.
    by Helmut Greim, Michael Arand, Herman Autrup, Hermann M Bolt, James Bridges, Erik Dybing, Rã©mi Glomot, Vito Foa, Rolf Schulte-Hermann
    posted to animal_studies reach risk_assessment toxicology by wandall on 2007-02-15 15:26:14 as **
  • Large effects from small exposures. II. The importance of positive controls in low-dose research on bisphenol A
    Environmental Research, Vol. 100, No. 1. (January 2006), pp. 50-76.
    by Vom, Wade V Welshons
    posted to bias toxicology by wandall on 2006-11-09 15:26:07 as read
  • Ethics For Toxicologists: An Examination of Conscience
    pp. 390-392.
    by JJ Saady
    posted to ethics toxicology by wandall on 2006-11-09 19:48:49 as read
  • Fraud, errors and gamesmanship in experimental toxicology
    Toxicology, Vol. 202, No. 1-2. (30 September 2004), pp. 1-20.
    by Iain F Purchase
    posted to bias fraud toxicology by wandall on 2006-11-09 15:14:49 as read
  • Diagnosis: Toxic! - Trying to Apply Approaches of Clinical Diagnostics and Prevalence in Toxicology Considerations
    Toxicological Sciences, Vol. 85, No. 1. (15 May 2005), pp. 422-428.
    by Sebastian Hoffmann, Thomas Hartung
    posted to ebt evidence-based toxicology by wandall on 2006-11-09 19:11:32 as ***
  • Influence of design characteristics on the outcome of retrospective cohort studies.
    Br J Ind Med, Vol. 45, No. 9. (September 1988), pp. 624-629.
    by GM Swaen, JM Meijers
    posted to cohort_studies epidemiology statistics study_design toxicology by wandall on 2006-11-10 12:36:32 as read
  • Dioxins: An overview
    Environmental Research, Vol. 101, No. 3. (July 2006), pp. 419-428.
    by Arnold Schecter, Linda Birnbaum, John J Ryan, John D Constable
    posted to dioxine toxicology by wandall on 2006-11-09 15:18:28 as ** along with 1 person ph_schecter
  • Prediction, Explanation, and Dioxin Biochemistry: Science in Public Policy
    Foundations of Chemistry, Vol. V6, No. 1. (1 January 2004), pp. 49-63.
    by Heather Douglas
    posted to uncertainty toxicology risk_assessment risk ra_guidelines prediction policy philosophy mechanism judgement false_positivefalse_negative explanation epa dioxine by wandall on 2006-11-09 13:43:13 as read
  • Workshop Proceedings: Managing Conflict of Interest in Science. A Little Consensus and A Lot of Controversy
    Toxicological Sciences, Vol. 87, No. 1. (September 2005), pp. 11-14.
    by Jacques P Maurissen, Steven G Gilbert, Miriam Sander, Tom L Beauchamp, Shelley Johnson, Bernard A Schwetz, Merrill Goozner, Craig S Barrow
    posted to conflict_of_interest toxicology by wandall on 2006-11-09 20:01:30 as **
  • How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
    Mutat Res, Vol. 628, No. 1. (30 March 2007), pp. 31-55.
    by D Kirkland, S Pfuhler, D Tweats, M Aardema, R Corvi, F Darroudi, A Elhajouji, H Glatt, P Hastwell, M Hayashi, P Kasper, S Kirchner, A Lynch, D Marzin, D Maurici, JR Meunier, L Müller, G Nohynek, J Parry, E Parry, V Thybaud, R Tice, J van Benthem, P Vanparys, P White
    posted to animal_studies false_positive in_vitro toxicology by wandall on 2007-04-27 13:49:43 as ** along with 1 person jyuh
  • The comparative power of the discriminant methods used in toxicological pathology.
    Toxicol Pathol, Vol. 33, No. 4. (2005), pp. 490-494.
    by T Holland
    posted to blinding histopathology scientific_method statistics toxicology by wandall on 2006-11-09 20:19:24 as read
  • Overview of male-mediated developmental toxicity.
    Adv Exp Med Biol, Vol. 518 (2003), pp. 11-24.
    by D Anderson
    posted to male-mediated paternal_exposure toxicity toxicology by uz_labu_laimi on 2007-03-26 18:38:47 as **
  • Reference Concentrations of Antidepressants. A Compilation of Postmortem and Therapeutic Levels
    Journal of Analytical Toxicology, Vol. 31, No. 5. (June 2007), pp. 254-264.
    by Reis, , Aamo, , Ahlner, , Druid,
    posted to antidepressants levels of toxicology by TCHanf on 2007-08-15 03:12:23 as **
  • Prediction of Nephrotoxicant Action and Identification of Candidate Toxicity-Related Biomarkers
    Toxicologic Pathology, Vol. 33, No. 3. (2005), pp. 343-355.
    by Sushi Thukral, Pau Nordone, Ron Hu, Lea Sullivan, Eri Galambos, Vincen Fitzpatrick, Laur Healy, Michae Bass, Mar Cosenza, Cynthi Afshari
    posted to genomics nephrotoxicity toxicology by shikin on 2007-10-18 18:08:56 as ** along with 1 person jyuh
  • The liver pharmacological and xenobiotic gene response repertoire
    Mol Syst Biol, Vol. 4 (25 March 2008)
    by Georges Natsoulis, Cecelia I Pearson, Jeremy Gollub, Eynon, Joe Ferng, Ramesh Nair, Radha Idury, May D Lee, Mark R Fielden, Richard J Brennan, Alan H Roter, Kurt Jarnagin
    posted to gene_expression iconix toxicology by shikin on 2008-07-03 15:26:40 as ** along with 5 people and 1 group jyuh zwang caseybrown aubinhon ptrobajo Integrative_biology_behavior
  • Overlapping gene expression profiles of model compounds provide opportunities for immunotoxicity screening.
    Toxicol Appl Pharmacol, Vol. 226, No. 1. (1 January 2008), pp. 46-59.
    by KA Baken, JL Pennings, MJ Jonker, MM Schaap, A de Vries, H van Steeg, TM Breit, H van Loveren
    posted to genego systems_biology toxicology by shikin on 2008-02-18 15:25:59 as **
  • A novel method for visualizing nuclear hormone receptor networks relevant to drug metabolism.
    Drug metabolism and disposition: the biological fate of chemicals, Vol. 33, No. 3. (March 2005), pp. 474-481.
    by S Ekins, E Kirillov, EA Rakhmatulin, T Nikolskaya
    posted to genego network systems_biology toxicology by shikin on 2008-05-04 13:19:07 as ** along with 1 group GeneGo
  • Nephrotoxicity of aminoglycoside antibiotics.
    Toxicol Lett, Vol. 46, No. 1-3. (March 1989), pp. 107-123.
    by PM Tulkens
    posted to nephrotoxicity toxicology by shikin on 2007-10-18 18:06:01 as **
  • A gene expression signature that predicts the future onset of drug-induced renal tubular toxicity.
    Toxicol Pathol, Vol. 33, No. 6. (2005), pp. 675-683.
    by MR Fielden, BP Eynon, G Natsoulis, K Jarnagin, D Banas, KL Kolaja
    posted to genomics nephrotoxicity toxicology by shikin on 2007-10-18 18:01:40 as read along with 1 person jdiggans
  • The promise of toxicogenomics.
    Curr Opin Mol Ther, Vol. 4, No. 3. (June 2002), pp. 229-235.
    by JF Waring, DN Halbert
    posted to nephrotoxicity toxicology by shikin on 2007-10-18 13:31:49 as **
  • Assessment of renal function--glomerular and tubular.
    Clin Lab Med, Vol. 13, No. 1. (March 1993), pp. 33-52.
    by CG Duarte, HG Preuss
    posted to nephrotoxicity thesis toxicology by shikin on 2007-10-09 18:02:29 as ***
  • Cyclosporine nephropathy: pathophysiology and clinical impact.
    Semin Nephrol, Vol. 16, No. 6. (November 1996), pp. 536-547.
    by FS Shihab
    posted to nephrotoxicity thesis toxicology by shikin on 2007-10-09 17:39:02 as ***
  • Early prediction of drug metabolism and toxicity: systems biology approach and modeling.
    Drug Discov Today, Vol. 9, No. 3. (1 February 2004), pp. 127-135.
    by A Bugrim, T Nikolskaya, Y Nikolsky
    posted to genego systems_biology toxicology by shikin on 2008-02-18 15:30:46 as ** along with 1 person kuhn
  • Identification of putative gene based markers of renal toxicity.
    Environ Health Perspect, Vol. 112, No. 4. (March 2004), pp. 465-479.
    by RP Amin, AE Vickers, F Sistare, KL Thompson, RJ Roman, M Lawton, J Kramer, HK Hamadeh, J Collins, S Grissom, L Bennett, CJ Tucker, S Wild, C Kind, V Oreffo, JW Davis, S Curtiss, JM Naciff, M Cunningham, R Tennant, J Stevens, B Car, TA Bertram, CA Afshari
    posted to genomics nephrotoxicity toxicology by shikin on 2007-10-18 15:08:03 as ** along with 1 person jyuh
  • Quantitative gene expression analysis in a nonhuman primate model of antibiotic-induced nephrotoxicity.
    Toxicol Appl Pharmacol, Vol. 200, No. 1. (1 October 2004), pp. 16-26.
    by JW Davis, FM Goodsaid, CM Bral, LA Obert, G Mandakas, CE Garner, ND Collins, RJ Smith, IY Rosenblum
    posted to nephrotoxicity thesis toxicology by shikin on 2007-10-09 18:22:27 as **
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