Atomic force microscopy probing of cell elasticity Export

@article{T.Kuznetsova.Rev.2007, abstract = {Atomic force microscopy (AFM) has recently provided the great progress in the study of micro- and nanostructures including living cells and cell organelles. Modern AFM techniques allow solving a number of problems of cell biomechanics due to simultaneous evaluation of the local mechanical properties and the topography of the living cells at a high spatial resolution and force sensitivity. Particularly, force spectroscopy is used for mapping mechanical properties of a single cell that provides information on cellular structures including cytoskeleton structure. This entry is aimed to review the recent AFM applications for the study of dynamics and mechanical properties of intact cells associated with different cell events such as locomotion, differentiation and aging, physiological activation and electromotility, as well as cell pathology. Local mechanical characteristics of different cell types including muscle cells, endothelial and epithelial cells, neurons and glial cells, fibroblasts and osteoblasts, blood cells and sensory cells are analyzed in this paper.}, author = {Kuznetsova, T. and Starodubtseva, M. and Yegorenkov, N. and Chizhik, S. and Zhdanov, R.}, citeulike-article-id = {4030052}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.micron.2007.06.011}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0968432807001047}, doi = {10.1016/j.micron.2007.06.011}, issn = {09684328}, journal = {Micron}, keywords = {atomic, cell, cytoskeleton, dynamics, elasticity, force, microscopy, modulus, youngs}, month = {December}, number = {8}, pages = {824--833}, posted-at = {2009-11-06 14:33:20}, priority = {2}, title = {Atomic force microscopy probing of cell elasticity}, url = {http://dx.doi.org/10.1016/j.micron.2007.06.011}, volume = {38}, year = {2007} }

TY - JOUR ID - T.Kuznetsova.Rev.2007 L3 - citeulike-article-id:4030052 N2 - Atomic force microscopy (AFM) has recently provided the great progress in the study of micro- and nanostructures including living cells and cell organelles. Modern AFM techniques allow solving a number of problems of cell biomechanics due to simultaneous evaluation of the local mechanical properties and the topography of the living cells at a high spatial resolution and force sensitivity. Particularly, force spectroscopy is used for mapping mechanical properties of a single cell that provides information on cellular structures including cytoskeleton structure. This entry is aimed to review the recent AFM applications for the study of dynamics and mechanical properties of intact cells associated with different cell events such as locomotion, differentiation and aging, physiological activation and electromotility, as well as cell pathology. Local mechanical characteristics of different cell types including muscle cells, endothelial and epithelial cells, neurons and glial cells, fibroblasts and osteoblasts, blood cells and sensory cells are analyzed in this paper. IS - 8 JF - Micron SN - 09684328 EP - 833 TI - Atomic force microscopy probing of cell elasticity VL - 38 SP - 824 KW - atomic KW - cell KW - cytoskeleton KW - dynamics KW - elasticity KW - force KW - microscopy KW - modulus KW - youngs AU - Kuznetsova, T AU - Starodubtseva, M AU - Yegorenkov, N AU - Chizhik, S AU - Zhdanov, R PY - 2007/12// UR - http://dx.doi.org/10.1016/j.micron.2007.06.011 ER -