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Determination of Group A Streptococcal Anti-M Type-Specific Antibody in Sera of Rheumatic Fever Patients after 45 Years.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Vol. 0, No. 0. (17 September 2009), pp. 000-000.
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AbstractGroup A streptococcal M type-specific protective antibodies-especially their persistence in humans-are incompletely understood. Such information is essential for understanding the epidemiology and pathogenesis of these infections and their sequelae and is equally crucial for producing a group A streptococcal vaccine. We studied 2 adults for type-specific antibody 45 years after they experienced documented rheumatic fever.
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