Frequency of CCR5delta32 in Brazilian populations. Export

@article{citeulike:562852, abstract = {A sample of 103 randomly chosen healthy individuals from Alegrete, RS, Brazil, was tested for the CCR5delta32 allele, which is known to influence susceptibility to HIV-1 infection. The CCR5delta32 allele was identified by PCR amplification using specific primers flanking the region of deletion, followed by electrophoresis on a 3\% agarose gel. The data obtained were compared to those reported for other populations and interpreted in terms of Brazilian history. The individuals studied came from a highly admixed population. Most of them were identified as white (N = 59), while blacks and browns (mulattoes) were N = 13 and N = 31, respectively. The observed frequencies, considering the white, black and brown samples (6.8, 3.8, and 6.4\%, respectively), suggest an important European parental contribution, even in populations identified as black and brown. However, in Brazil as a whole, this allele shows gradients indicating a relatively good correlation with the classification based on skin color and other physical traits, used here to define major Brazilian population groups.}, address = {Departamento de Gen\'{e}tica, Instituto de Bioci\^{e}ncias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.}, author = {Vargas, A. E. and Marrero, A. R. and Salzano, F. M. and Bortolini, M. C. and Chies, J. A.}, citeulike-article-id = {562852}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/16501811}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=16501811}, issn = {0100-879X}, journal = {Braz J Med Biol Res}, keywords = {autosomal, brazil, ccr5, delta-32}, month = {March}, number = {3}, pages = {321--325}, posted-at = {2006-03-25 07:13:12}, priority = {5}, title = {Frequency of CCR5delta32 in Brazilian populations.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/16501811}, volume = {39}, year = {2006} }

TY - JOUR ID - citeulike:562852 L3 - citeulike-article-id:562852 N2 - A sample of 103 randomly chosen healthy individuals from Alegrete, RS, Brazil, was tested for the CCR5delta32 allele, which is known to influence susceptibility to HIV-1 infection. The CCR5delta32 allele was identified by PCR amplification using specific primers flanking the region of deletion, followed by electrophoresis on a 3% agarose gel. The data obtained were compared to those reported for other populations and interpreted in terms of Brazilian history. The individuals studied came from a highly admixed population. Most of them were identified as white (N = 59), while blacks and browns (mulattoes) were N = 13 and N = 31, respectively. The observed frequencies, considering the white, black and brown samples (6.8, 3.8, and 6.4%, respectively), suggest an important European parental contribution, even in populations identified as black and brown. However, in Brazil as a whole, this allele shows gradients indicating a relatively good correlation with the classification based on skin color and other physical traits, used here to define major Brazilian population groups. IS - 3 JF - Braz J Med Biol Res SN - 0100-879X AD - Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil. EP - 325 TI - Frequency of CCR5delta32 in Brazilian populations. VL - 39 SP - 321 KW - autosomal KW - brazil KW - ccr5 KW - delta-32 AU - Vargas, AE AU - Marrero, AR AU - Salzano, FM AU - Bortolini, MC AU - Chies, JA PY - 2006/03// UR - http://view.ncbi.nlm.nih.gov/pubmed/16501811 ER -