Jewish and Middle Eastern non-Jewish populations share a common pool of Y-chromosome biallelic haplotypes. Export

@article{citeulike:802672, abstract = {Haplotypes constructed from Y-chromosome markers were used to trace the paternal origins of the Jewish Diaspora. A set of 18 biallelic polymorphisms was genotyped in 1,371 males from 29 populations, including 7 Jewish (Ashkenazi, Roman, North African, Kurdish, Near Eastern, Yemenite, and Ethiopian) and 16 non-Jewish groups from similar geographic locations. The Jewish populations were characterized by a diverse set of 13 haplotypes that were also present in non-Jewish populations from Africa, Asia, and Europe. A series of analyses was performed to address whether modern Jewish Y-chromosome diversity derives mainly from a common Middle Eastern source population or from admixture with neighboring non-Jewish populations during and after the Diaspora. Despite their long-term residence in different countries and isolation from one another, most Jewish populations were not significantly different from one another at the genetic level. Admixture estimates suggested low levels of European Y-chromosome gene flow into Ashkenazi and Roman Jewish communities. A multidimensional scaling plot placed six of the seven Jewish populations in a relatively tight cluster that was interspersed with Middle Eastern non-Jewish populations, including Palestinians and Syrians. Pairwise differentiation tests further indicated that these Jewish and Middle Eastern non-Jewish populations were not statistically different. The results support the hypothesis that the paternal gene pools of Jewish communities from Europe, North Africa, and the Middle East descended from a common Middle Eastern ancestral population, and suggest that most Jewish communities have remained relatively isolated from neighboring non-Jewish communities during and after the Diaspora.}, address = {Laboratory of Molecular Systematics and Evolution, University of Arizona, Tucson, AZ 85721, USA. mhammer@u.arizona.edu}, author = {Hammer, M. F. and Redd, A. J. and Wood, E. T. and Bonner, M. R. and Jarjanazi, H. and Karafet, T. and Santachiara-Benerecetti, S. and Oppenheim, A. and Jobling, M. A. and Jenkins, T. and Ostrer, H. and Bonne-Tamir, B.}, citeulike-article-id = {802672}, citeulike-linkout-0 = {http://dx.doi.org/10.1073/pnas.100115997}, citeulike-linkout-1 = {http://www.pnas.org/content/97/12/6769.abstract}, citeulike-linkout-2 = {http://www.pnas.org/content/97/12/6769.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/10801975}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=10801975}, day = {6}, doi = {10.1073/pnas.100115997}, issn = {0027-8424}, journal = {Proc Natl Acad Sci U S A}, keywords = {ashkenazi, ethiopian, jews, kurdish, near\_easternyemenite, north\_african, roman, y}, month = {June}, number = {12}, pages = {6769--6774}, posted-at = {2006-08-16 13:19:19}, priority = {0}, title = {Jewish and Middle Eastern non-Jewish populations share a common pool of Y-chromosome biallelic haplotypes.}, url = {http://dx.doi.org/10.1073/pnas.100115997}, volume = {97}, year = {2000} }

TY - JOUR ID - citeulike:802672 L3 - citeulike-article-id:802672 N2 - Haplotypes constructed from Y-chromosome markers were used to trace the paternal origins of the Jewish Diaspora. A set of 18 biallelic polymorphisms was genotyped in 1,371 males from 29 populations, including 7 Jewish (Ashkenazi, Roman, North African, Kurdish, Near Eastern, Yemenite, and Ethiopian) and 16 non-Jewish groups from similar geographic locations. The Jewish populations were characterized by a diverse set of 13 haplotypes that were also present in non-Jewish populations from Africa, Asia, and Europe. A series of analyses was performed to address whether modern Jewish Y-chromosome diversity derives mainly from a common Middle Eastern source population or from admixture with neighboring non-Jewish populations during and after the Diaspora. Despite their long-term residence in different countries and isolation from one another, most Jewish populations were not significantly different from one another at the genetic level. Admixture estimates suggested low levels of European Y-chromosome gene flow into Ashkenazi and Roman Jewish communities. A multidimensional scaling plot placed six of the seven Jewish populations in a relatively tight cluster that was interspersed with Middle Eastern non-Jewish populations, including Palestinians and Syrians. Pairwise differentiation tests further indicated that these Jewish and Middle Eastern non-Jewish populations were not statistically different. The results support the hypothesis that the paternal gene pools of Jewish communities from Europe, North Africa, and the Middle East descended from a common Middle Eastern ancestral population, and suggest that most Jewish communities have remained relatively isolated from neighboring non-Jewish communities during and after the Diaspora. IS - 12 JF - Proc Natl Acad Sci U S A SN - 0027-8424 AD - Laboratory of Molecular Systematics and Evolution, University of Arizona, Tucson, AZ 85721, USA. mhammer@u.arizona.edu EP - 6774 TI - Jewish and Middle Eastern non-Jewish populations share a common pool of Y-chromosome biallelic haplotypes. VL - 97 SP - 6769 KW - ashkenazi KW - ethiopian KW - jews KW - kurdish KW - near_easternyemenite KW - north_african KW - roman KW - y AU - Hammer, MF AU - Redd, AJ AU - Wood, ET AU - Bonner, MR AU - Jarjanazi, H AU - Karafet, T AU - Santachiara-Benerecetti, S AU - Oppenheim, A AU - Jobling, MA AU - Jenkins, T AU - Ostrer, H AU - Bonne-Tamir, B PY - 2000/06/06/ UR - http://dx.doi.org/10.1073/pnas.100115997 ER -