Cortex Controls Multisensory Depression in Superior Colliculus Export

@article{citeulike:409427, abstract = {Multisensory depression is a fundamental index of multisensory integration in superior colliculus (SC) neurons. It is initiated when one sensory stimulus (auditory) located outside its modality-specific receptive field degrades or eliminates the neuron's responses to another sensory stimulus (visual) presented within its modality-specific receptive field. The present experiments demonstrate that the capacity of SC neurons to engage in multisensory depression is strongly dependent on influences from two cortical areas (the anterior ectosylvian and rostral lateral suprasylvian sulci). When these cortices are deactivated, the ability of SC neurons to synthesize visual-auditory inputs in this way is compromised; multisensory responses are disinhibited, becoming more vigorous and in some cases indistinguishable from responses to the visual stimulus alone. Although obtaining a more robust multisensory SC response when cortex is nonfunctional than when it is functional may seem paradoxical, these data may help explain previous observations that the loss of these cortical influences permits visual orientation behavior in the presence of a normally disruptive auditory stimulus.}, author = {Jiang, Wan and Stein, Barry E.}, citeulike-article-id = {409427}, citeulike-linkout-0 = {http://dx.doi.org/10.1152/jn.00369.2003}, citeulike-linkout-1 = {http://jn.physiology.org/cgi/content/abstract/90/4/2123}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/14534263}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=14534263}, day = {1}, doi = {10.1152/jn.00369.2003}, journal = {J Neurophysiol}, keywords = {aes, cat, cortical\_influence, recordings, superior\_colliculus}, month = {October}, number = {4}, pages = {2123--2135}, posted-at = {2008-10-21 10:00:06}, priority = {2}, title = {Cortex Controls Multisensory Depression in Superior Colliculus}, url = {http://dx.doi.org/10.1152/jn.00369.2003}, volume = {90}, year = {2003} }

TY - JOUR ID - citeulike:409427 L3 - citeulike-article-id:409427 N2 - Multisensory depression is a fundamental index of multisensory integration in superior colliculus (SC) neurons. It is initiated when one sensory stimulus (auditory) located outside its modality-specific receptive field degrades or eliminates the neuron's responses to another sensory stimulus (visual) presented within its modality-specific receptive field. The present experiments demonstrate that the capacity of SC neurons to engage in multisensory depression is strongly dependent on influences from two cortical areas (the anterior ectosylvian and rostral lateral suprasylvian sulci). When these cortices are deactivated, the ability of SC neurons to synthesize visual-auditory inputs in this way is compromised; multisensory responses are disinhibited, becoming more vigorous and in some cases indistinguishable from responses to the visual stimulus alone. Although obtaining a more robust multisensory SC response when cortex is nonfunctional than when it is functional may seem paradoxical, these data may help explain previous observations that the loss of these cortical influences permits visual orientation behavior in the presence of a normally disruptive auditory stimulus. IS - 4 JF - J Neurophysiol EP - 2135 TI - Cortex Controls Multisensory Depression in Superior Colliculus VL - 90 SP - 2123 KW - aes KW - cat KW - cortical_influence KW - recordings KW - superior_colliculus AU - Jiang, Wan AU - Stein, Barry PY - 2003/10/01/ UR - http://dx.doi.org/10.1152/jn.00369.2003 ER -