Proteins and cells on PEG immobilized silicon surfaces Export

@article{miqin_peg_98, abstract = {Silicon surfaces were modified by covalent attachment of a self-assembled (SA) polyethylene glycol (PEG) film. Adsorption of albumin, fibrinogen, and IgG to PEG immobilized silicon surfaces was studied by ellipsometry to evaluate the non-fouling and non-immunogenic properties of the surfaces. The adhesion and proliferation of human fibroblast and Hela cells onto the modified surfaces were investigated to examine their tissue biocompatibility. Coated PEG chains showed the effective depression of both plasma protein adsorption and cell attachment to the modified surfaces. The mechanisms accounting for the reduction of protein adsorption and cell adhesion on modified surfaces were discussed.}, author = {Miqin, Z.}, citeulike-article-id = {6075425}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/S0142-9612(98)00026-X}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0142-9612(98)00026-X}, doi = {10.1016/S0142-9612(98)00026-X}, issn = {01429612}, journal = {Biomaterials}, keywords = {adsorption, angle, cell, chloro, contact, ellipsometry, peg, protein, silane, silicon}, month = {May}, number = {10}, pages = {953--960}, posted-at = {2009-11-05 17:03:51}, priority = {2}, title = {Proteins and cells on PEG immobilized silicon surfaces}, url = {http://dx.doi.org/10.1016/S0142-9612(98)00026-X}, volume = {19}, year = {1998} }

TY - JOUR ID - miqin_peg_98 L3 - citeulike-article-id:6075425 N2 - Silicon surfaces were modified by covalent attachment of a self-assembled (SA) polyethylene glycol (PEG) film. Adsorption of albumin, fibrinogen, and IgG to PEG immobilized silicon surfaces was studied by ellipsometry to evaluate the non-fouling and non-immunogenic properties of the surfaces. The adhesion and proliferation of human fibroblast and Hela cells onto the modified surfaces were investigated to examine their tissue biocompatibility. Coated PEG chains showed the effective depression of both plasma protein adsorption and cell attachment to the modified surfaces. The mechanisms accounting for the reduction of protein adsorption and cell adhesion on modified surfaces were discussed. IS - 10 JF - Biomaterials SN - 01429612 EP - 960 TI - Proteins and cells on PEG immobilized silicon surfaces VL - 19 SP - 953 KW - adsorption KW - angle KW - cell KW - chloro KW - contact KW - ellipsometry KW - peg KW - protein KW - silane KW - silicon AU - Miqin, Z PY - 1998/05// UR - http://dx.doi.org/10.1016/S0142-9612(98)00026-X ER -