Surface plasmon resonance mass spectrometry: recent progress and outlooks Export

@article{citeulike:5903748, abstract = {The combination of surface plasmon resonance (SPR) and mass spectrometry (MS) has created a unique approach to protein investigations. Surface plasmon resonance is used to quantify interactions between proteins and surface-immobilized ligands, and MS is used to determine the structural features of the bound proteins. Recent progress in SPR–MS includes improved methods and operations, increased limits of detection, multi-protein analysis and protein-complex delineation. With the subsequent design of SPR protein arrays, SPR–MS is expected to enter into the field of high-throughput protein interaction discovery and miniaturized diagnostics.}, author = {Nedelkov, Dobrin and Nelson, Randall W.}, citeulike-article-id = {5903748}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/S0167-7799(03)00141-0}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0167-7799(03)00141-0}, doi = {10.1016/S0167-7799(03)00141-0}, issn = {01677799}, journal = {Trends in Biotechnology}, keywords = {id-qd, mass-spectrometry, pa, spr}, month = {July}, number = {7}, pages = {301--305}, posted-at = {2009-10-06 21:57:51}, priority = {2}, title = {Surface plasmon resonance mass spectrometry: recent progress and outlooks}, url = {http://dx.doi.org/10.1016/S0167-7799(03)00141-0}, volume = {21}, year = {2003} }

TY - JOUR ID - citeulike:5903748 L3 - citeulike-article-id:5903748 N2 - The combination of surface plasmon resonance (SPR) and mass spectrometry (MS) has created a unique approach to protein investigations. Surface plasmon resonance is used to quantify interactions between proteins and surface-immobilized ligands, and MS is used to determine the structural features of the bound proteins. Recent progress in SPR–MS includes improved methods and operations, increased limits of detection, multi-protein analysis and protein-complex delineation. With the subsequent design of SPR protein arrays, SPR–MS is expected to enter into the field of high-throughput protein interaction discovery and miniaturized diagnostics. IS - 7 JF - Trends in Biotechnology SN - 01677799 EP - 305 TI - Surface plasmon resonance mass spectrometry: recent progress and outlooks VL - 21 SP - 301 KW - id-qd KW - mass-spectrometry KW - pa KW - spr AU - Nedelkov, Dobrin AU - Nelson, Randall PY - 2003/07// UR - http://dx.doi.org/10.1016/S0167-7799(03)00141-0 ER -