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Nat Struct Mol Biol, Vol. 19, No. 2. (08 February 2012), pp. 193-200, doi:10.1038/nsmb.2205 Key: citeulike:10312552
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The processivity of myosins and kinesins has been well studied, but how the dynein homodimer achieves continuous motion is unknown. Two-dimensional analysis of labeled, DNA-dimerized dynein demonstrates that dynein has an unusual stepping pattern and can alternate between stochastic- and tension-based stepping to achieve processivity.
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