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An Age-Structured Model of Pre- and Post-Vaccination Measles Transmission Export

Math Med Biol, Vol. 1, No. 2. (1 January 1984), pp. 169-191.

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An infection like measles does not spread uniformly in populations from Europe and North America. Of special importance is a pronounced age-dependency in the contact rates, because of increased infection transmission within schools. Therefore an age-structured epidemiologic model is investigated here, which also pays attention to the fact that children are promoted grade-wise into and out of school. Simulation results are contrasted with pre- and post-vaccination measles data from England and Wales and the model is shown to perform better than previous global mass-action models. 10.1093/imammb/1.2.169


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