Diabetic peripheral neuropathy: Amelioration of pain with transcutaneous electrostimulation Export

@article{citeulike:4960331, abstract = {OBJECTIVE - To evaluate the efficacy of transcutaneous electrotherapy for chronic painful peripheral neuropathy in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS - Thirty-one patients with symptoms and signs of peripheral neuropathy were randomized to the electrotherapy or sham treatment (control) group. The electrostimulation was given by a portable unit (H-Wave machine) that generated a biphasic, exponentially decaying waveform (pulse width 4 ms, 25-35 V, ≤2 Hz). Patients treated each of their lower extremities for 30 min daily for 4 weeks at home. Nine patients from the sham-treatment group participated for a second period, during which all of them received the active electrotherapy. Patient's degree of pain and discomfort was graded on a scale of 0 to 5. RESULTS - In the sham-treated group (n = 13), the neuropathic symptoms improved in five (38\%) patients, and the pain score declined from 2.92 ± 0.13 to 2.38 ± 0.26 (P < 0.04), suggesting a procedure-related placebo effect. In the electrotherapy group (n = 18), symptomatic improvement was seen in 15 (83\%) cases, 3 of which were completely asymptomatic; the pain score declined from 3.17 ± 0.12 to 1.44 ± 0.25 (P < 0.01) and the posttreatment pain scores were considerably lower (P < 0.03), indicating a substantial treatment effect over and above any placebo influence. Patients in the electrotherapy group reported greater reduction in symptoms (52 ± 7\% vs. 27 ± 10\% in control subjects, P < 0.05) on an analog scale. Moreover, the electrotherapy decreased pain scores (from 3.0 ± 0.62 to 1.56 ± 0.32, P < 0.02) in nine patients who had received sham treatment earlier. CONCLUSIONS - A form of transcutaneous electrotherapy ameliorated the pain and discomfort associated with peripheral neuropathy. This novel modality offers a potential non-pharmacological treatment option.}, author = {Kumar, D.}, citeulike-article-id = {4960331}, citeulike-linkout-0 = {http://ovidsp.tx.ovid.com/spa/ovidweb.cgi?&#38;S=ODENFPPCBADDMLAONCFLHCPLODIKAA00&#38;Abstract=S.sh.15.16.19.40%7c16%7c1}, issn = {0149-5992}, journal = {Diabetes care}, keywords = {diabetic, dpn, e-stim, electrical, electrostimulation, intervention, nerve, neuropathic, neuropathy, pain, paresthesia, peripheral, physical\_therapy, physiotherapy, sensation, sensation\_intervention, sensation\_treatment, sensory, sensory\_intervention, sensory\_treatment, stimulation, tactile, transcutaneous, treatment}, number = {11}, pages = {1702--1705}, posted-at = {2009-06-25 20:38:56}, priority = {2}, title = {Diabetic peripheral neuropathy: Amelioration of pain with transcutaneous electrostimulation}, url = {http://ovidsp.tx.ovid.com/spa/ovidweb.cgi?&#38;S=ODENFPPCBADDMLAONCFLHCPLODIKAA00&#38;Abstract=S.sh.15.16.19.40%7c16%7c1}, volume = {20}, year = {1997} }

TY - JOUR ID - citeulike:4960331 L3 - citeulike-article-id:4960331 N2 - OBJECTIVE - To evaluate the efficacy of transcutaneous electrotherapy for chronic painful peripheral neuropathy in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS - Thirty-one patients with symptoms and signs of peripheral neuropathy were randomized to the electrotherapy or sham treatment (control) group. The electrostimulation was given by a portable unit (H-Wave machine) that generated a biphasic, exponentially decaying waveform (pulse width 4 ms, 25-35 V, ≤2 Hz). Patients treated each of their lower extremities for 30 min daily for 4 weeks at home. Nine patients from the sham-treatment group participated for a second period, during which all of them received the active electrotherapy. Patient's degree of pain and discomfort was graded on a scale of 0 to 5. RESULTS - In the sham-treated group (n = 13), the neuropathic symptoms improved in five (38%) patients, and the pain score declined from 2.92 ± 0.13 to 2.38 ± 0.26 (P < 0.04), suggesting a procedure-related placebo effect. In the electrotherapy group (n = 18), symptomatic improvement was seen in 15 (83%) cases, 3 of which were completely asymptomatic; the pain score declined from 3.17 ± 0.12 to 1.44 ± 0.25 (P < 0.01) and the posttreatment pain scores were considerably lower (P < 0.03), indicating a substantial treatment effect over and above any placebo influence. Patients in the electrotherapy group reported greater reduction in symptoms (52 ± 7% vs. 27 ± 10% in control subjects, P < 0.05) on an analog scale. Moreover, the electrotherapy decreased pain scores (from 3.0 ± 0.62 to 1.56 ± 0.32, P < 0.02) in nine patients who had received sham treatment earlier. CONCLUSIONS - A form of transcutaneous electrotherapy ameliorated the pain and discomfort associated with peripheral neuropathy. This novel modality offers a potential non-pharmacological treatment option. IS - 11 JF - Diabetes care SN - 0149-5992 EP - 1705 TI - Diabetic peripheral neuropathy: Amelioration of pain with transcutaneous electrostimulation VL - 20 SP - 1702 KW - diabetic KW - dpn KW - e-stim KW - electrical KW - electrostimulation KW - intervention KW - nerve KW - neuropathic KW - neuropathy KW - pain KW - paresthesia KW - peripheral KW - physical_therapy KW - physiotherapy KW - sensation KW - sensation_intervention KW - sensation_treatment KW - sensory KW - sensory_intervention KW - sensory_treatment KW - stimulation KW - tactile KW - transcutaneous KW - treatment AU - Kumar, D PY - 1997/// UR - http://ovidsp.tx.ovid.com/spa/ovidweb.cgi?&#38;S=ODENFPPCBADDMLAONCFLHCPLODIKAA00&#38;Abstract=S.sh.15.16.19.40%7c16%7c1 ER -