Make Your Diabetic Patients Walk: Long-term impact of different amounts of physical activity on type 2 diabetes TeX Export

@article{citeulike:5013743, abstract = {OBJECTIVE: To establish the impact of different amounts of increased energy expenditure on type 2 diabetes care. RESEARCH DESIGN AND METHODS: Post hoc analysis of long-term effects of different amounts of increased energy expenditure (metabolic equivalents [METS] per hour per week) through voluntary aerobic physical activity was performed in 179 type 2 diabetic subjects (age 62 ± 1 years [mean ± SE]) randomized to a physical activity counseling intervention. Subjects were followed for 2 years and divided into six groups based on their increments in METs per hour per week: group 0 (no activity, n = 28), group 1–10 (6.8 ± 0.3, n = 27), group 11–20 (17.1 ± 0.4, n = 31), group 21–30 (27.0 ± 0.5, n = 27), group 31–40 (37.5 ± 0.5, n = 32), and group >40 (58.3 ± 1.8, n = 34). RESULTS: At baseline, the six groups did not differ for energy expenditure, age, sex, diabetes duration, and all parameters measured. After 2 years, in group 0 and in group 1–10, no parameter changed; in groups 11–20, 21–30, 31–40, and >40, HbA1c, blood pressure, total serum cholesterol, triglycerides, and estimated percent of 10-year coronary heart disease risk improved (P < 0.05). In group 21–30, 31–40, and >40, body weight, waist circumference, heart rate, fasting plasma glucose, serum LDL and HDL cholesterol also improved (P < 0.05). METs per hour per week correlated positively with changes of HDL cholesterol and negatively with those of other parameters (P < 0.001). After 2 years, per capita yearly costs of medications increased (P = 0.008) by \$393 in group 0, did not significantly change in group 1–10 (\$206, P = 0.09), and decreased in group 11–20 (-\$196, P = 0.01), group 21–30 (-\$593, P = 0.009), group 31–40 (-\$660, P = 0.003), and group >40 (-\$579, P = 0.001). CONCLUSIONS: Energy expenditure >10 METs · h-1 · week-1 obtained through aerobic leisure time physical activity is sufficient to achieve health and financial advantages, but full benefits are achieved with energy expenditure >20 METs · h-1 · week-1.}, author = {Di}, citeulike-article-id = {5013743}, issn = {0149-5992}, journal = {Diabetes care}, keywords = {diabetic\_peripheral\_neuropathy, dpn, energy, exercise, expenditure, intervention, mets, neuropathic\_pain, paresthesia\_intervention, paresthesia\_treatment, peripheral\_diabetic\_neuropathy, physical\_therapy, physiotherapy, sensation\_intervention, sensation\_treatment, sensory\_intervention, sensory\_treatment, treatment}, number = {6}, pages = {1295--1302}, posted-at = {2009-06-29 16:53:46}, priority = {2}, title = {Make Your Diabetic Patients Walk: Long-term impact of different amounts of physical activity on type 2 diabetes}, volume = {28} }

TY - JOUR ID - citeulike:5013743 L3 - citeulike-article-id:5013743 N2 - OBJECTIVE: To establish the impact of different amounts of increased energy expenditure on type 2 diabetes care. RESEARCH DESIGN AND METHODS: Post hoc analysis of long-term effects of different amounts of increased energy expenditure (metabolic equivalents [METS] per hour per week) through voluntary aerobic physical activity was performed in 179 type 2 diabetic subjects (age 62 ± 1 years [mean ± SE]) randomized to a physical activity counseling intervention. Subjects were followed for 2 years and divided into six groups based on their increments in METs per hour per week: group 0 (no activity, n = 28), group 1–10 (6.8 ± 0.3, n = 27), group 11–20 (17.1 ± 0.4, n = 31), group 21–30 (27.0 ± 0.5, n = 27), group 31–40 (37.5 ± 0.5, n = 32), and group >40 (58.3 ± 1.8, n = 34). RESULTS: At baseline, the six groups did not differ for energy expenditure, age, sex, diabetes duration, and all parameters measured. After 2 years, in group 0 and in group 1–10, no parameter changed; in groups 11–20, 21–30, 31–40, and >40, HbA1c, blood pressure, total serum cholesterol, triglycerides, and estimated percent of 10-year coronary heart disease risk improved (P < 0.05). In group 21–30, 31–40, and >40, body weight, waist circumference, heart rate, fasting plasma glucose, serum LDL and HDL cholesterol also improved (P < 0.05). METs per hour per week correlated positively with changes of HDL cholesterol and negatively with those of other parameters (P < 0.001). After 2 years, per capita yearly costs of medications increased (P = 0.008) by $393 in group 0, did not significantly change in group 1–10 ($206, P = 0.09), and decreased in group 11–20 (-$196, P = 0.01), group 21–30 (-$593, P = 0.009), group 31–40 (-$660, P = 0.003), and group >40 (-$579, P = 0.001). CONCLUSIONS: Energy expenditure >10 METs · h-1 · week-1 obtained through aerobic leisure time physical activity is sufficient to achieve health and financial advantages, but full benefits are achieved with energy expenditure >20 METs · h-1 · week-1. IS - 6 JF - Diabetes care SN - 0149-5992 EP - 1302 TI - Make Your Diabetic Patients Walk: Long-term impact of different amounts of physical activity on type 2 diabetes VL - 28 SP - 1295 KW - diabetic_peripheral_neuropathy KW - dpn KW - energy KW - exercise KW - expenditure KW - intervention KW - mets KW - neuropathic_pain KW - paresthesia_intervention KW - paresthesia_treatment KW - peripheral_diabetic_neuropathy KW - physical_therapy KW - physiotherapy KW - sensation_intervention KW - sensation_treatment KW - sensory_intervention KW - sensory_treatment KW - treatment AU - Di ER -