Mathematical description of synergistic interaction of UV light and hyperthermia for yeast cells. Export

@article{citeulike:6075148, abstract = {A new mathematical model for the synergistic interaction of lesions produced by ultraviolet (UV) light and high temperature has been proposed. The model suggests that synergism is expected from the additional lethal lesions arising from the interaction of sublesions induced by both agents. These sublesions are considered noneffective after each agent is taken alone. The model predicts the dependence of the synergistic interaction on the ratio of lethal lesions produced by each agent applied, the greatest value of the synergistic effect as well as the conditions under which it can be achieved, and the dependence of synergistic effect on UV light fluence rate. These predictions of the model have been tested for the simultaneous combined action of UV light (wavelength 254 nm) and heat (45-57.5 degrees C) on two strains of wild-type diploid yeast cells of Saccharomyces cerevisiae. The theory appears to be appropriate and the conclusions valid.}, author = {Petin, V. G. and Kim, J. K. and Zhurakovskaya, G. P. and Rassokhina, A. V.}, citeulike-article-id = {6075148}, citeulike-linkout-0 = {http://www.biomedexperts.com/Abstract.bme/10877071}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/10877071}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=10877071}, issn = {1011-1344}, journal = {Journal of photochemistry and photobiology. B, Biology}, keywords = {heat, model, synergy, uv, yeast}, month = {March}, number = {1}, pages = {74--79}, posted-at = {2009-11-05 16:28:19}, priority = {2}, title = {Mathematical description of synergistic interaction of UV light and hyperthermia for yeast cells.}, url = {http://www.biomedexperts.com/Abstract.bme/10877071}, volume = {55}, year = {2000} }

TY - JOUR ID - citeulike:6075148 L3 - citeulike-article-id:6075148 N2 - A new mathematical model for the synergistic interaction of lesions produced by ultraviolet (UV) light and high temperature has been proposed. The model suggests that synergism is expected from the additional lethal lesions arising from the interaction of sublesions induced by both agents. These sublesions are considered noneffective after each agent is taken alone. The model predicts the dependence of the synergistic interaction on the ratio of lethal lesions produced by each agent applied, the greatest value of the synergistic effect as well as the conditions under which it can be achieved, and the dependence of synergistic effect on UV light fluence rate. These predictions of the model have been tested for the simultaneous combined action of UV light (wavelength 254 nm) and heat (45-57.5 degrees C) on two strains of wild-type diploid yeast cells of Saccharomyces cerevisiae. The theory appears to be appropriate and the conclusions valid. IS - 1 JF - Journal of photochemistry and photobiology. B, Biology SN - 1011-1344 EP - 79 TI - Mathematical description of synergistic interaction of UV light and hyperthermia for yeast cells. VL - 55 SP - 74 KW - heat KW - model KW - synergy KW - uv KW - yeast AU - Petin, VG AU - Kim, JK AU - Zhurakovskaya, GP AU - Rassokhina, AV PY - 2000/03// UR - http://www.biomedexperts.com/Abstract.bme/10877071 ER -