Complex population structure in African village dogs and its implications for inferring dog domestication history Export

@article{citeulike:5656402, abstract = {10.1073/pnas.0902129106 High genetic diversity of East Asian village dogs has recently been used to argue for an East Asian origin of the domestic dog. However, global village dog genetic diversity and the extent to which semiferal village dogs represent distinct, indigenous populations instead of admixtures of various dog breeds has not been quantified. Understanding these issues is critical to properly reconstructing the timing, number, and locations of dog domestication. To address these questions, we sampled 318 village dogs from 7 regions in Egypt, Uganda, and Namibia, measuring genetic diversity >680 bp of the mitochondrial D-loop, 300 SNPs, and 89 microsatellite markers. We also analyzed breed dogs, including putatively African breeds (Afghan hounds, Basenjis, Pharaoh hounds, Rhodesian ridgebacks, and Salukis), Puerto Rican street dogs, and mixed breed dogs from the United States. Village dogs from most African regions appear genetically distinct from non-native breed and mixed-breed dogs, although some individuals cluster genetically with Puerto Rican dogs or United States breed mixes instead of with neighboring village dogs. Thus, African village dogs are a mosaic of indigenous dogs descended from early migrants to Africa, and non-native, breed-admixed individuals. Among putatively African breeds, Pharaoh hounds, and Rhodesian ridgebacks clustered with non-native rather than indigenous African dogs, suggesting they have predominantly non-African origins. Surprisingly, we find similar mtDNA haplotype diversity in African and East Asian village dogs, potentially calling into question the hypothesis of an East Asian origin for dog domestication.}, author = {Boyko, Adam R. and Boyko, Ryan H. and Boyko, Corin M. and Parker, Heidi G. and Castelhano, Marta and Corey, Liz and Degenhardt, Jeremiah D. and Auton, Adam and Hedimbi, Marius and Kityo, Robert and Ostrander, Elaine A. and Schoenebeck, Jeffrey and Todhunter, Rory J. and Jones, Paul and Bustamante, Carlos D.}, citeulike-article-id = {5656402}, citeulike-linkout-0 = {http://dx.doi.org/10.1073/pnas.0902129106}, citeulike-linkout-1 = {http://www.pnas.org/content/106/33/13903.abstract}, citeulike-linkout-2 = {http://www.pnas.org/content/106/33/13903.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/19666600}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=19666600}, day = {18}, doi = {10.1073/pnas.0902129106}, journal = {Proceedings of the National Academy of Sciences}, keywords = {200908, afrique, archeozoologie, domestication}, month = {August}, number = {33}, pages = {13903--13908}, posted-at = {2009-08-27 10:56:14}, priority = {2}, title = {Complex population structure in African village dogs and its implications for inferring dog domestication history}, url = {http://dx.doi.org/10.1073/pnas.0902129106}, volume = {106}, year = {2009} }

TY - JOUR ID - citeulike:5656402 L3 - citeulike-article-id:5656402 N2 - 10.1073/pnas.0902129106 High genetic diversity of East Asian village dogs has recently been used to argue for an East Asian origin of the domestic dog. However, global village dog genetic diversity and the extent to which semiferal village dogs represent distinct, indigenous populations instead of admixtures of various dog breeds has not been quantified. Understanding these issues is critical to properly reconstructing the timing, number, and locations of dog domestication. To address these questions, we sampled 318 village dogs from 7 regions in Egypt, Uganda, and Namibia, measuring genetic diversity >680 bp of the mitochondrial D-loop, 300 SNPs, and 89 microsatellite markers. We also analyzed breed dogs, including putatively African breeds (Afghan hounds, Basenjis, Pharaoh hounds, Rhodesian ridgebacks, and Salukis), Puerto Rican street dogs, and mixed breed dogs from the United States. Village dogs from most African regions appear genetically distinct from non-native breed and mixed-breed dogs, although some individuals cluster genetically with Puerto Rican dogs or United States breed mixes instead of with neighboring village dogs. Thus, African village dogs are a mosaic of indigenous dogs descended from early migrants to Africa, and non-native, breed-admixed individuals. Among putatively African breeds, Pharaoh hounds, and Rhodesian ridgebacks clustered with non-native rather than indigenous African dogs, suggesting they have predominantly non-African origins. Surprisingly, we find similar mtDNA haplotype diversity in African and East Asian village dogs, potentially calling into question the hypothesis of an East Asian origin for dog domestication. IS - 33 JF - Proceedings of the National Academy of Sciences EP - 13908 TI - Complex population structure in African village dogs and its implications for inferring dog domestication history VL - 106 SP - 13903 KW - 200908 KW - afrique KW - archeozoologie KW - domestication AU - Boyko, Adam AU - Boyko, Ryan AU - Boyko, Corin AU - Parker, Heidi AU - Castelhano, Marta AU - Corey, Liz AU - Degenhardt, Jeremiah AU - Auton, Adam AU - Hedimbi, Marius AU - Kityo, Robert AU - Ostrander, Elaine AU - Schoenebeck, Jeffrey AU - Todhunter, Rory AU - Jones, Paul AU - Bustamante, Carlos PY - 2009/08/18/ UR - http://dx.doi.org/10.1073/pnas.0902129106 ER -