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Methods in molecular biology (Clifton, N.J.), Vol. 802 (2012), pp. 249-257, doi:10.1007/978-1-61779-400-1_16 Key: citeulike:10092741
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Next generation sequencing is a common and versatile tool for biological and medical research. We describe the basic steps for analyzing next generation sequencing data, including quality checking and mapping to a reference genome. We also explain the further data analysis for three common applications of next generation sequencing: variant detection, RNA-seq, and ChIP-seq.
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