Results from a pediatric surgical centre justify early intervention in disorders of sex development Export

@article{citeulike:5390723, abstract = {Controversy persists surrounding early management of disorders of sex development. We assessed genital appearance, gender identity, and quality of life in prepubertal children who have had early surgical intervention. Children treated for disorders of sex development who were 5 to 10 years of age were eligible (n = 54). Children were scored (modified Creighton scale) for anatomical and cosmetic outcome, and both patients and parents completed PedsQL quality-of-life and gender identity questionnaires, with ethics approval. Of 54 patients, 41 presented for review. Treatment began at 13.2 (1.8-250.1) months (median; range) and were reviewed at 7.5 ± 2.1 (mean ± SD) years of age. Nineteen were raised as girls and 22 as boys. Girls had good (85\%) or satisfactory (15\%) anatomical/cosmetic outcome, whereas 52\% boys had good, 38\% satisfactory, and 10\% poor cosmetic outcomes. On gender identity questionnaire, boys scored 3.9 ± 0.4 (mean ± SD) and girls 3.6 ± 0.5; 1 of 19 boys and 3 of 19 girls had lower scores, suggesting risk of gender identity disorder. Quality-of-life scores were 80+ for physical and 65 to 80 for psychosocial scores. Early intervention is generally associated with positive outcomes for patients and parents. Girls had better anatomical outcomes than boys, and gender dysphoria risks were low in both sexes.}, author = {Crawford, Jennifer M. and Warne, Garry and Grover, Sonia and Southwell, Bridget R. and Hutson, John M.}, citeulike-article-id = {5390723}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.jpedsurg.2008.10.101}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0022346808009652}, doi = {10.1016/j.jpedsurg.2008.10.101}, issn = {00223468}, journal = {Journal of Pediatric Surgery}, keywords = {abuse, dsd, dsm, icd, minors}, month = {February}, number = {2}, pages = {413--416}, posted-at = {2009-08-07 06:48:25}, priority = {2}, title = {Results from a pediatric surgical centre justify early intervention in disorders of sex development}, url = {http://dx.doi.org/10.1016/j.jpedsurg.2008.10.101}, volume = {44}, year = {2009} }

TY - JOUR ID - citeulike:5390723 L3 - citeulike-article-id:5390723 N2 - Controversy persists surrounding early management of disorders of sex development. We assessed genital appearance, gender identity, and quality of life in prepubertal children who have had early surgical intervention. Children treated for disorders of sex development who were 5 to 10 years of age were eligible (n = 54). Children were scored (modified Creighton scale) for anatomical and cosmetic outcome, and both patients and parents completed PedsQL quality-of-life and gender identity questionnaires, with ethics approval. Of 54 patients, 41 presented for review. Treatment began at 13.2 (1.8-250.1) months (median; range) and were reviewed at 7.5 ± 2.1 (mean ± SD) years of age. Nineteen were raised as girls and 22 as boys. Girls had good (85%) or satisfactory (15%) anatomical/cosmetic outcome, whereas 52% boys had good, 38% satisfactory, and 10% poor cosmetic outcomes. On gender identity questionnaire, boys scored 3.9 ± 0.4 (mean ± SD) and girls 3.6 ± 0.5; 1 of 19 boys and 3 of 19 girls had lower scores, suggesting risk of gender identity disorder. Quality-of-life scores were 80+ for physical and 65 to 80 for psychosocial scores. Early intervention is generally associated with positive outcomes for patients and parents. Girls had better anatomical outcomes than boys, and gender dysphoria risks were low in both sexes. IS - 2 JF - Journal of Pediatric Surgery SN - 00223468 EP - 416 TI - Results from a pediatric surgical centre justify early intervention in disorders of sex development VL - 44 SP - 413 KW - abuse KW - dsd KW - dsm KW - icd KW - minors AU - Crawford, Jennifer AU - Warne, Garry AU - Grover, Sonia AU - Southwell, Bridget AU - Hutson, John PY - 2009/02// UR - http://dx.doi.org/10.1016/j.jpedsurg.2008.10.101 ER -