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HEIRS's Song:C [3 articles]

 
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Potential enzyme toxicity of perfluorooctanoic acid.

  [CiTO]
Amino acids, Vol. 38, No. 1. (January 2010), pp. 113-120, doi:10.1007/s00726-008-0217-4
posted to no-tag by HEIRS  on 2010-04-05 02:13:01 *** along with 1 group HEIRS - Environmental Illness Research

Abstract

Using equilibrium dialysis, isothermal titration calorimetry (ITC) and circular dichroism (CD), the interactions of perfluorooctanoic acid (PFOA) and lysozyme were investigated under normal human physiological conditions, i.e., at pH 4.40, 6.00 and 7.40 at 37 degrees C in 0.15 M electrolyte. A simple and rapid spectrophotometric method was developed for determining PFOA concentrations. Interactions between PFOA and lysozyme were found to result from non-specific non-covalent bonds-F/N and F/O affinity, ion-pair attraction, hydrogen bond, hydrophobic interaction and van der Waals force-and were ...

 

THE EFFECTS OF PSYCHOLOGICAL STRESS ON HUMANS: INCREASED PRODUCTION OF PRO-INFLAMMATORY CYTOKINES AND Th1-LIKE RESPONSE IN STRESS-INDUCED ANXIETY

  [CiTO]
Cytokine, Vol. 10, No. 4. (April 1998), pp. 313-318
posted to anxiety cytokines inflammation stress th1 by HEIRS  on 2009-03-08 01:46:08 *** along with 2 people and 4 groups diogocandeo mtf5024 HEIRS - Environmental Illness Research HEIRS Cellular Biology HEIRS Immunology and Autoimmune Diseases HEIRS Psychology and Psychotherapy
 

Mast Cells can Mediate Vascular Permeability through Regulation of PI3K-HIF-1-VEGF Axis

  [CiTO]
Am. J. Respir. Crit. Care Med (31 July 2008)
posted to mast_cells pi3k vascular_permeability by HEIRS  on 2008-09-09 16:01:51 *** along with 1 group HEIRS - Environmental Illness Research

Abstract

Bronchial inflammation is usually accompanied by increased vascular permeability. Mast cells release a number of mediators that act directly on the vasculature, resulting in vasodilatation, increased permeability, and subsequent plasma protein extravasation. Vascular endothelial growth factor (VEGF) has been implicated to contribute to asthmatic tissue edema through its effect on vascular permeability. However, the effects of mast cells on VEGF-mediated signaling in allergic airway disease are not clearly understood. Objectives: An aim of the present study was to investigate the role ...

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