Gut flora and bacterial translocation in chronic liver disease. Export

@article{citeulike:3074880, abstract = {Increasing evidence suggests that derangement of gut flora is of substantial clinical relevance to patients with cirrhosis. Intestinal bacterial overgrowth and increased bacterial translocation of gut flora from the intestinal lumen, in particular, predispose to an increased potential for bacterial infection in this group. Recent studies suggest that, in addition to their role in the pathogenesis of overt infective episodes and the clinical consequences of sepsis, gut flora contributes to the pro-inflammatory state of cirrhosis even in the absence of overt infection. Furthermore, manipulation of gut flora to augment the intestinal content of lactic acid-type bacteria at the expense of other gut flora species with more pathogenic potential may favourably influence liver function in cirrhotic patients. Here we review current concepts of the various inter-relationships between gut flora, bacterial translocation, bacterial infection, pro-inflammatory cytokine production and liver function in this group.}, author = {Almeida, J. and Galhenage, S. and Yu, J. and Kurtovic, J. and Riordan, S. M.}, citeulike-article-id = {3074880}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/16570339}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=16570339}, day = {14}, issn = {1007-9327}, journal = {World journal of gastroenterology : WJG}, keywords = {bacterial\_translocation, cirrhosis, gut, liver, microbiology}, month = {March}, number = {10}, pages = {1493--1502}, posted-at = {2008-08-01 21:00:14}, priority = {2}, title = {Gut flora and bacterial translocation in chronic liver disease.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/16570339}, volume = {12}, year = {2006} }

TY - JOUR ID - citeulike:3074880 L3 - citeulike-article-id:3074880 N2 - Increasing evidence suggests that derangement of gut flora is of substantial clinical relevance to patients with cirrhosis. Intestinal bacterial overgrowth and increased bacterial translocation of gut flora from the intestinal lumen, in particular, predispose to an increased potential for bacterial infection in this group. Recent studies suggest that, in addition to their role in the pathogenesis of overt infective episodes and the clinical consequences of sepsis, gut flora contributes to the pro-inflammatory state of cirrhosis even in the absence of overt infection. Furthermore, manipulation of gut flora to augment the intestinal content of lactic acid-type bacteria at the expense of other gut flora species with more pathogenic potential may favourably influence liver function in cirrhotic patients. Here we review current concepts of the various inter-relationships between gut flora, bacterial translocation, bacterial infection, pro-inflammatory cytokine production and liver function in this group. IS - 10 JF - World journal of gastroenterology : WJG SN - 1007-9327 EP - 1502 TI - Gut flora and bacterial translocation in chronic liver disease. VL - 12 SP - 1493 KW - bacterial_translocation KW - cirrhosis KW - gut KW - liver KW - microbiology AU - Almeida, J AU - Galhenage, S AU - Yu, J AU - Kurtovic, J AU - Riordan, SM PY - 2006/03/14/ UR - http://view.ncbi.nlm.nih.gov/pubmed/16570339 ER -