CMOS DNA Sensor Array With Integrated A/D Conversion Based on Label-Free Capacitance Measurement Export

@article{citeulike:5720491, abstract = {This paper presents a fully electronic label-free DNA chip in 0.5-mum CMOS technology, with 5-V supply voltage, suitable for low-cost highly integrated applications. The chip features an array of 128 sensor sites with gold electrodes and integrated measurement, conditioning, multiplexing and analog-to-digital conversion circuitry. The circuits measure capacitance variations due to DNA hybridization on the gold electrodes which are bio-modified by covalently attaching probes of known sequence. Specificity, repeatability and parallel detection capability of the fabricated chip are successfully demonstrated}, author = {Stagni, C. and Guiducci, C. and Benini, L. and Ricco, B. and Carrara, S. and Samori, B. and Paulus, C. and Schienle, M. and Augustyniak, M. and Thewes, R.}, booktitle = {Solid-State Circuits, IEEE Journal of}, citeulike-article-id = {5720491}, citeulike-linkout-0 = {http://dx.doi.org/10.1109/JSSC.2006.884867}, citeulike-linkout-1 = {http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=4014638}, doi = {10.1109/JSSC.2006.884867}, journal = {Solid-State Circuits, IEEE Journal of}, keywords = {capacitance, cmos, dna, impedance}, number = {12}, pages = {2956--2964}, posted-at = {2009-09-04 01:55:16}, priority = {2}, title = {CMOS DNA Sensor Array With Integrated A/D Conversion Based on Label-Free Capacitance Measurement}, url = {http://dx.doi.org/10.1109/JSSC.2006.884867}, volume = {41}, year = {2006} }

TY - JOUR ID - citeulike:5720491 L3 - citeulike-article-id:5720491 N2 - This paper presents a fully electronic label-free DNA chip in 0.5-mum CMOS technology, with 5-V supply voltage, suitable for low-cost highly integrated applications. The chip features an array of 128 sensor sites with gold electrodes and integrated measurement, conditioning, multiplexing and analog-to-digital conversion circuitry. The circuits measure capacitance variations due to DNA hybridization on the gold electrodes which are bio-modified by covalently attaching probes of known sequence. Specificity, repeatability and parallel detection capability of the fabricated chip are successfully demonstrated IS - 12 JF - Solid-State Circuits, IEEE Journal of EP - 2964 TI - CMOS DNA Sensor Array With Integrated A/D Conversion Based on Label-Free Capacitance Measurement VL - 41 T2 - Solid-State Circuits, IEEE Journal of SP - 2956 KW - capacitance KW - cmos KW - dna KW - impedance AU - Stagni, C AU - Guiducci, C AU - Benini, L AU - Ricco, B AU - Carrara, S AU - Samori, B AU - Paulus, C AU - Schienle, M AU - Augustyniak, M AU - Thewes, R PY - 2006/// UR - http://dx.doi.org/10.1109/JSSC.2006.884867 ER -