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Biochip for DNA Amplification and Label-free DNA Detection Export

Sensors, 2007 IEEE In Sensors, 2007 IEEE (2007), pp. 724-727.

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capacitance cmos dna pcr

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A silicon-glass based DNA micro analysis system is demonstrated. This biochip is able to amplify and detect specific DNA. First a PCR is run in a micro chamber to generate DNA copies from a specific target gene (16 rRNA). Afterwards the PCR solution is put on a capacitive DNA sensing area where target DNA hybridization is detected. The sensor consists of functionalized nanoscaled interdigitated electrodes for label-free DNA recognition. This biochemical analysis system is able to detect pathogenic bacteria in a miniaturized, cost effective and fast way.


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