Was nitric oxide the first deep electron sink? Export

@article{citeulike:3551748, abstract = {Evolutionary histories of enzymes involved in chemiosmotic energy conversion indicate that a strongly oxidizing substrate was available to the last universal common ancestor before the divergence of Bacteria and Archaea. According to palaeogeochemical evidence, O(2) was not present beyond trace amounts on the early Earth. Based on recent phylogenetic, enzymatic and geochemical results, we propose that, in the earliest Archaean, nitric oxide (NO) and its derivatives nitrate and nitrite served as strongly oxidizing substrates driving the evolution of a bioenergetic pathway related to modern dissimilatory denitrification. Aerobic respiration emerged later from within this ancestral pathway via adaptation of the enzyme NO reductase to its new substrate, dioxygen.}, author = {Ducluzeau, A. and Vanlis, R. and Duval, S. and Schoeppcothenet, B. and Russell, M. and Nitschke, W.}, citeulike-article-id = {3551748}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.tibs.2008.10.005}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0968000408002363}, day = {12}, doi = {10.1016/j.tibs.2008.10.005}, issn = {09680004}, journal = {Trends in Biochemical Sciences}, keywords = {biochemistry, cytochromes, early\_earth, evolution, no, oxidase}, month = {November}, posted-at = {2008-11-17 10:34:55}, priority = {4}, title = {Was nitric oxide the first deep electron sink?}, url = {http://dx.doi.org/10.1016/j.tibs.2008.10.005}, year = {2008} }

TY - JOUR ID - citeulike:3551748 L3 - citeulike-article-id:3551748 N2 - Evolutionary histories of enzymes involved in chemiosmotic energy conversion indicate that a strongly oxidizing substrate was available to the last universal common ancestor before the divergence of Bacteria and Archaea. According to palaeogeochemical evidence, O(2) was not present beyond trace amounts on the early Earth. Based on recent phylogenetic, enzymatic and geochemical results, we propose that, in the earliest Archaean, nitric oxide (NO) and its derivatives nitrate and nitrite served as strongly oxidizing substrates driving the evolution of a bioenergetic pathway related to modern dissimilatory denitrification. Aerobic respiration emerged later from within this ancestral pathway via adaptation of the enzyme NO reductase to its new substrate, dioxygen. JF - Trends in Biochemical Sciences SN - 09680004 TI - Was nitric oxide the first deep electron sink? KW - biochemistry KW - cytochromes KW - early_earth KW - evolution KW - no KW - oxidase AU - Ducluzeau, A AU - Vanlis, R AU - Duval, S AU - Schoeppcothenet, B AU - Russell, M AU - Nitschke, W PY - 2008/11/12/ UR - http://dx.doi.org/10.1016/j.tibs.2008.10.005 ER -