Protein function prediction--the power of multiplicity. Export

@article{citeulike:4220969, abstract = {Advances in experimental and computational methods have quietly ushered in a new era in protein function annotation. This 'age of multiplicity' is marked by the notion that only the use of multiple tools, multiple evidence and considering the multiple aspects of function can give us the broad picture that 21st century biology will need to link and alter micro- and macroscopic phenotypes. It might also help us to undo past mistakes by removing errors from our databases and prevent us from producing more. On the downside, multiplicity is often confusing. We therefore systematically review methods and resources for automated protein function prediction, looking at individual (biochemical) and contextual (network) functions, respectively.}, author = {Rentzsch, Robert and Orengo, Christine A.}, citeulike-article-id = {4220969}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.tibtech.2009.01.002}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0167779909000377}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19251332}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19251332}, day = {27}, doi = {10.1016/j.tibtech.2009.01.002}, issn = {0167-7799}, journal = {Trends in biotechnology}, keywords = {annotation, genome, proteomics, review}, month = {April}, number = {4}, pages = {210--219}, posted-at = {2009-03-31 10:34:31}, priority = {2}, title = {Protein function prediction--the power of multiplicity.}, url = {http://dx.doi.org/10.1016/j.tibtech.2009.01.002}, volume = {27}, year = {2009} }

TY - JOUR ID - citeulike:4220969 L3 - citeulike-article-id:4220969 N2 - Advances in experimental and computational methods have quietly ushered in a new era in protein function annotation. This 'age of multiplicity' is marked by the notion that only the use of multiple tools, multiple evidence and considering the multiple aspects of function can give us the broad picture that 21st century biology will need to link and alter micro- and macroscopic phenotypes. It might also help us to undo past mistakes by removing errors from our databases and prevent us from producing more. On the downside, multiplicity is often confusing. We therefore systematically review methods and resources for automated protein function prediction, looking at individual (biochemical) and contextual (network) functions, respectively. IS - 4 JF - Trends in biotechnology SN - 0167-7799 EP - 219 TI - Protein function prediction--the power of multiplicity. VL - 27 SP - 210 KW - annotation KW - genome KW - proteomics KW - review AU - Rentzsch, Robert AU - Orengo, Christine PY - 2009/04/27/ UR - http://dx.doi.org/10.1016/j.tibtech.2009.01.002 ER -