Adaptation of core mechanisms to generate cell polarity. Export

@article{citeulike:3477038, abstract = {Cell polarity is defined as asymmetry in cell shape, protein distributions and cell functions. It is characteristic of single-cell organisms, including yeast and bacteria, and cells in tissues of multi-cell organisms such as epithelia in worms, flies and mammals. This diversity raises several questions: do different cell types use different mechanisms to generate polarity, how is polarity signalled, how do cells react to that signal, and how is structural polarity translated into specialized functions? Analysis of evolutionarily diverse cell types reveals that cell-surface landmarks adapt core pathways for cytoskeleton assembly and protein transport to generate cell polarity.}, author = {Nelson, W. James}, citeulike-article-id = {3477038}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nature01602}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nature01602}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/12700771}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=12700771}, day = {17}, doi = {10.1038/nature01602}, issn = {0028-0836}, journal = {Nature}, keywords = {adaptation, common, core, mechanism, polarity, review}, month = {April}, number = {6933}, pages = {766--774}, posted-at = {2008-11-03 22:10:01}, priority = {2}, title = {Adaptation of core mechanisms to generate cell polarity.}, url = {http://dx.doi.org/10.1038/nature01602}, volume = {422}, year = {2003} }

TY - JOUR ID - citeulike:3477038 L3 - citeulike-article-id:3477038 N2 - Cell polarity is defined as asymmetry in cell shape, protein distributions and cell functions. It is characteristic of single-cell organisms, including yeast and bacteria, and cells in tissues of multi-cell organisms such as epithelia in worms, flies and mammals. This diversity raises several questions: do different cell types use different mechanisms to generate polarity, how is polarity signalled, how do cells react to that signal, and how is structural polarity translated into specialized functions? Analysis of evolutionarily diverse cell types reveals that cell-surface landmarks adapt core pathways for cytoskeleton assembly and protein transport to generate cell polarity. IS - 6933 JF - Nature SN - 0028-0836 EP - 774 TI - Adaptation of core mechanisms to generate cell polarity. VL - 422 SP - 766 KW - adaptation KW - common KW - core KW - mechanism KW - polarity KW - review AU - Nelson, James PY - 2003/04/17/ UR - http://dx.doi.org/10.1038/nature01602 ER -