LamBras's nmda [58 articles] Export

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	5-aminomethylquinoxaline-2,3-diones. Part II: N-aryl derivatives as novel NMDA/glycine and AMPA antagonists [My Copy] Bioorganic & Medicinal Chemistry Letters, Vol. 8, No. 1. (06 January 1998), pp. 71-74. by Y. Auberson posted to nmda by LamBras on 2009-03-29 12:58:40 as
	A Novel Series of 2-Carboxytetrahydroquinolines Provides New Insights into the Eastern Region of Glycine Site NMDA Antagonists [My Copy] Archiv der Pharmazie, Vol. 333, No. 8. (2000), pp. 267-274. by Gerd Dannhardt, Markus, Beate K. Kohl, C. G. Parsons posted to nmda by LamBras on 2008-12-22 19:44:37 as
	6,7,8,9-tetrahydro-3-hydroxy-1H-1-benzazepine-2,5-diones via a diels-alder reaction:antagonists with a non-planar hydrophobic region for NMDA receptor glycine sites [My Copy] Bioorganic & Medicinal Chemistry Letters, Vol. 5, No. 22. (16 November 1995), pp. 2747-2748. by A. Guzikowski posted to nmda by LamBras on 2008-12-22 18:49:36 as
	Novel pyrrolinones as -methyl--aspartate receptor antagonists [My Copy] European Journal of Medicinal Chemistry, Vol. 40, No. 4. (April 2005), pp. 391-400. by H. Poschenrieder, H. Stachel, G. Hofner, P. Mayer posted to nmda by LamBras on 2008-12-22 18:46:07 as
	A novel series of 2-carboxytetrahydroquinolines provides new insights into the eastern region of glycine site NMDA antagonists. [My Copy] Archiv der Pharmazie, Vol. 333, No. 8. (August 2000), pp. 267-274. by G. Dannhardt, M. von Gruchalla, B. K. Kohl, C. G. Parsons posted to nmda nr1 by LamBras on 2008-12-21 13:11:26 as
	Principles of Selective Ion Transport in Channels and Pumps [My Copy] Science, Vol. 310, No. 5753. (2 December 2005), pp. 1461-1465. by Eric Gouaux, Roderick Mackinnon posted to nmda by LamBras on 2008-12-21 12:35:46 as along with 1 person and 2 groups barry structural_bioinformatics Bioinformatics
	Subtype selectivity and flexibility of ionotropic glutamate receptors upon antagonist ligand binding [My Copy] Org. Biomol. Chem., Vol. 4, No. 6. (2006), pp. 1058-1070. by Ulla Pentikainen, Luca Settimo, Mark S. Johnson, Olli T. Pentikainen posted to flexibility nmda by LamBras on 2008-12-20 17:12:27 as
	GlycineB recognition site of NMDA receptors and its antagonists. [My Copy] Amino acids, Vol. 14, No. 1-3. (1998), pp. 205-206. by W. Danysz, C. G. Parsons posted to nmda by LamBras on 2008-12-20 15:43:06 as
	Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit. [My Copy] Neuron, Vol. 18, No. 3. (March 1997), pp. 493-503. by B. Laube, H. Hirai, M. Sturgess, H. Betz, J. Kuhse posted to nmda by LamBras on 2008-12-20 15:41:38 as
	Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes [My Copy] Science, Vol. 241, No. 4867. (12 August 1988), pp. 835-837. by N. W. Kleckner, R. Dingledine posted to nmda by LamBras on 2008-12-20 15:39:37 as
	Evidence for a Tetrameric Structure of Recombinant NMDA Receptors [My Copy] J. Neurosci., Vol. 18, No. 8. (15 April 1998), pp. 2954-2961. by Bodo Laube, Jochen Kuhse, Heinrich Betz posted to nmda by LamBras on 2008-12-20 15:33:56 as
	Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain [My Copy] Science, Vol. 226, No. 4676. (16 November 1984), pp. 850-852. by R. P. Simon, J. H. Swan, T. Griffiths, B. S. Meldrum posted to nmda by LamBras on 2008-12-20 15:32:07 as
	NMDA receptor hypofunction model of schizophrenia [My Copy] Journal of Psychiatric Research, Vol. 33, No. 6. (December 1999), pp. 523-533. by J. Olney posted to nmda by LamBras on 2008-12-20 15:27:02 as
	The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence [My Copy] International Journal of Geriatric Psychiatry, Vol. 18, No. S1. (2003), pp. S23-S32. by Wojciech Danysz, Chris G. Parsons posted to nmda by LamBras on 2008-12-20 15:24:22 as
	Density and distribution of NMDA receptors in the human hippocampus in Alzheimer's disease. [My Copy] Brain research, Vol. 399, No. 1. (3 December 1986), pp. 156-161. by J. W. Geddes, H. Chang-Chui, S. M. Cooper, I. T. Lott, C. W. Cotman posted to nmda by LamBras on 2008-12-20 15:23:15 as
	N-methyl-D-aspartate antagonists in the treatment of Parkinson's disease. [My Copy] Archives of neurology, Vol. 48, No. 9. (September 1991), pp. 977-981. by J. T. Greenamyre, C. F. O'Brien posted to nmda by LamBras on 2008-12-20 15:20:31 as
	Excitatory Amino Acid Transmitters [My Copy] Annual Review of Pharmacology and Toxicology, Vol. 21, No. 1. (1981), pp. 165-204. by J. C. Watkins, R. H. Evans posted to nmda by LamBras on 2008-12-20 15:14:56 as
	Glutamate activates multiple single channel conductances in hippocampal neurons [My Copy] Nature, Vol. 325, No. 6104. (5 February 1987), pp. 522-525. by C. E. Jahr, C. F. Stevens posted to nmda by LamBras on 2008-12-20 15:13:55 as
	Multiple-conductance channels activated by excitatory amino acids in cerebellar neurons. [My Copy] Nature, Vol. 325, No. 6104. (1 1987), pp. 525-528. by S. G. Cull-Candy, M. M. Usowicz posted to nmda by LamBras on 2008-12-20 15:13:47 as along with 1 person lenov
	Magnesium gates glutamate-activated channels in mouse central neurones [My Copy] Nature, Vol. 307, No. 5950. (2 February 1984), pp. 462-465. by L. Nowak, P. Bregestovski, P. Ascher, A. Herbet, A. Prochiantz posted to nmda by LamBras on 2008-12-20 15:13:24 as
	Molecular cloning and characterization of the rat NMDA receptor [My Copy] Nature, Vol. 354, No. 6348. (7 November 1991), pp. 31-37. by Koki Moriyoshi, Masayuki Masu, Takahiro Ishii, Ryuichi Shigemoto, Noboru Mizuno, Shigetada Nakanishi posted to nmda by LamBras on 2008-12-20 15:12:26 as
	The NMDA receptor glycine modulatory site: a therapeutic target for improving cognition and reducing negative symptoms in schizophrenia [My Copy] Psychopharmacology, Vol. 174, No. 1. (1 June 2004), pp. 32-38. by Joseph T. Coyle, Guochuan Tsai posted to nmda by LamBras on 2008-11-22 12:21:23 as
	Contribution of astrocytes to hippocampal long-term potentiation through release of d-serine [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 25. (December 2003), pp. 15194-15199. by Yunlei Yang, Wooping Ge, Yiren Chen, et al.Zhijun Zhang, Wanhua Shen, Chienping Wu, Muming Poo, Shumin Duan posted to nmda serinracemase by LamBras on 2008-11-22 12:16:31 as
	On the role of NR3A in human NMDA receptors [My Copy] Physiology & Behavior, Vol. 92, No. 1-2. (September 2007), pp. 54-59. by M. Eriksson, A. Nilsson, H. Samuelsson, et al.E. Samuelsson, L. Mo, E. Akesson, E. Benedikz, E. Sundstrom posted to nmda by LamBras on 2008-11-22 11:54:06 as
	The co-agonist concept: is the NMDA-associated glycine receptor saturated in vivo? [My Copy] Life Sciences, Vol. 57, No. 4. (16 June 1995), pp. 301-310. by P. Wood posted to nmda by LamBras on 2008-11-22 11:53:06 as
	Effects of endogenous agonists, glycine and D-serine, on in vivo specific binding of [11C]L-703,717, a PET radioligand for the glycine-binding site of NMDA receptors [My Copy] Synapse, Vol. 50, No. 2. (2003), pp. 130-136. by Terushi Haradahira, Takashi Okauchi, Jun Maeda, et al.Ming-Rong Zhang, Toru Nishikawa, Ryouichi Konno, Kazutoshi Suzuki, Tetsuya Suhara posted to nmda by LamBras on 2008-11-22 11:51:09 as
	The N-methyl d-aspartate receptor glycine site and d-serine metabolism: an evolutionary perspective [My Copy] Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 359, No. 1446. (29 June 2004), pp. 943-964. by Michael J. Schell posted to nmda serinracemase by LamBras on 2008-11-22 11:44:49 as
	Neuron-derived D-Serine Release Provides a Novel Means to Activate N-Methyl-D-aspartate Receptors [My Copy] J. Biol. Chem., Vol. 281, No. 20. (19 May 2006), pp. 14151-14162. by Elena Kartvelishvily, Maria Shleper, Livia Balan, Elena Dumin, Herman Wolosker posted to nmda serinracemase by LamBras on 2008-11-22 11:36:58 as
	Immunocytochemical analysis of D-serine distribution in the mammalian brain reveals novel anatomical compartmentalizations in glia and neurons [My Copy] Glia, Vol. 53, No. 4. (2006), pp. 401-411. by Susan M. Williams, Claudia M. Diaz, Lauren T. Macnab, Robert K. P. Sullivan, David V. Pow posted to nmda serinracemase by LamBras on 2008-11-22 11:34:54 as
	A new strategy to decrease N-methyl-d-aspartate (NMDA) receptor coactivation: Inhibition of d-serine synthesis by converting serine racemase into an eliminase [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, No. 9. (24 April 2001), pp. 5294-5299. by Rogério Panizzutti, Joari De Miranda, Cátia S. Ribeiro, Simone Engelender, Herman Wolosker posted to nmda serinracemase by LamBras on 2008-11-22 11:25:39 as
	Glia-Derived d-Serine Controls NMDA Receptor Activity and Synaptic Memory [My Copy] Cell, Vol. 125, No. 4. (19 May 2006), pp. 775-784. by A. Panatier posted to nmda serinracemase by LamBras on 2008-11-22 11:22:07 as
	Mass spectrometrical analysis of human serine racemase in foetal brain [My Copy] Journal of Neural Transmission, Vol. 112, No. 6. (1 June 2005), pp. 805-811. by F. Hepner, A. Pollak, N. Ulfig, M. Yae-Kyung, G. Lubec posted to nmda racemase by LamBras on 2008-10-01 16:20:09 as
	Induction of serine racemase expression and D-serine release from microglia by amyloid beta-peptide [My Copy] Journal of Neuroinflammation, Vol. 1, No. 1. (2004) by Sheng Z. Wu, Angela Bodles, Mandy Porter, Sue W. Griffin, Anthony Basile, Steven Barger posted to nmda serinracemase by LamBras on 2008-10-01 16:19:10 as
	Mass spectrometrical analysis of human serine racemase in foetal brain [My Copy] Journal of Neural Transmission, Vol. 112, No. 6. (1 June 2005), pp. 805-811. by F. Hepner, A. Pollak, N. Ulfig, M. Yae-Kyung, G. Lubec posted to nmda racemase by LamBras on 2008-10-01 16:05:48 as
	Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-d-aspartate (NMDA) receptor coagonist d-serine [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 22. (29 October 2002), pp. 14542-14547. by Joari de Miranda, Rogerio Panizzutti, Veronika N. Foltyn, Herman Wolosker posted to nmda serinracemase by LamBras on 2008-10-01 16:05:02 as
	Serine racemase: Activation by glutamate neurotransmission via glutamate receptor interacting protein and mediation of neuronal migration [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, No. 6. (February 2005), pp. 2105-2110. by Paul M. Kim, Hiroyuki Aizawa, Peter S. Kim, et al.Alex S. Huang, Sasrutha R. Wickramasinghe, Amir H. Kashani, Roxanne K. Barrow, Richard L. Huganir, Anirvan Ghosh, Solomon H. Snyder posted to nmda serinracemase by LamBras on 2008-10-01 16:02:01 as
	Rules of engagement for NMDA receptor subunits [My Copy] Proceedings of the National Academy of Sciences, Vol. 105, No. 37. (2008), pp. 14163-14168. by Maximilian H. Ulbrich, Ehud Y. Isacoff posted to nmda review by LamBras on 2008-09-17 10:32:19 as
	NMDA receptors as targets for drug action in neuropathic pain [My Copy] European Journal of Pharmacology, Vol. 429, No. 1-3. (19 October 2001), pp. 71-78. by Chris G. Parsons posted to nmda by LamBras on 2008-08-15 12:28:37 as
	Probing the Mg2+ blockade site of an N-methyl-D-aspartate (NMDA) receptor with unnatural amino acid mutagenesis. [My Copy] ACS chemical biology, Vol. 1, No. 4. (23 May 2006), pp. 227-234. by K. A. McMenimen, D. A. Dougherty, H. A. Lester, E. J. Petersson posted to nmda by LamBras on 2008-07-24 15:33:23 as
	The Glycine Site on the NMDA Receptor: Structure-Activity Relationships and Therapeutic Potential [My Copy] Journal of Medicinal Chemistry, Vol. 37, No. 24. (1994), pp. 4053-4067. by Paul D. Leeson, Leslie L. Iversen posted to nmda nr1 by LamBras on 2008-07-23 17:07:26 as
	Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core. [My Copy] EMBO J, Vol. 22, No. 12. (16 June 2003), pp. 2873-2885. by H. Furukawa, E. Gouaux posted to docking ion_channels nmda nr1 sar by LamBras on 2008-07-20 16:10:50 as
	d -Serine is an endogenous ligand for the glycine site of the N -methyl- d -aspartate receptor [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, No. 9. (2000), pp. 4926-4931. by Jean P. Mothet, Angèle T. Parent, Herman Wolosker, et al.Roscoe O. Brady, David J. Linden, Christopher D. Ferris, Michael A. Rogawski, Solomon H. Snyder posted to nmda nr1 by LamBras on 2008-07-20 16:08:51 as
	On the Hypes and Falls in Neuroprotection: Targeting the NMDA Receptor [My Copy] Neuroscientist, Vol. 13, No. 6. (1 December 2007), pp. 594-615. by Carmen Villmann, Cord-Michael Becker posted to nmda review by LamBras on 2008-07-20 16:04:49 as along with 1 person carlafed
	N-Methyl-D-aspartate (NMDA) Receptor Subunit NR1 Forms the Substrate for Oligomeric Assembly of the NMDA Receptor [My Copy] J. Biol. Chem., Vol. 282, No. 35. (31 August 2007), pp. 25299-25307. by Palmi T. Atlason, Molly L. Garside, Elisabeth Meddows, Paul Whiting, Jeffrey R. A. Mcilhinney posted to nmda r1 by LamBras on 2008-07-20 16:04:13 as
	Structural Model of the N-Methyl-D-aspartate Receptor Glycine Site Probed by Site-directed Chemical Coupling [My Copy] J. Biol. Chem., Vol. 278, No. 26. (20 June 2003), pp. 24011-24017. by Bernard Foucaud, Bodo Laube, Rudolf Schemm, Annett Kreimeyer, Maurice Goeldner, Heinrich Betz posted to nmda nr1 by LamBras on 2008-07-20 16:03:56 as
	Expression and Initial Characterization of a Soluble Glycine Binding Domain of the N-Methyl-D-aspartate Receptor NR1 Subunit [My Copy] J. Biol. Chem., Vol. 273, No. 32. (7 August 1998), pp. 19933-19937. by Aleksandra Ivanovic, Helmut Reilander, Bodo Laube, Jochen Kuhse posted to nmda nr1 by LamBras on 2008-07-20 16:01:22 as
	Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands. [My Copy] Journal of structural biology, Vol. 145, No. 3. (March 2004), pp. 205-215. by L. Moretti, O. T. Pentikäinen, L. Settimo, M. S. Johnson posted to nmda by LamBras on 2008-07-20 15:33:32 as
	Structural Mobility of the Extracellular Ligand-Binding Core of an Ionotropic Glutamate Receptor. Analysis of NMR Relaxation Dynamics [My Copy] Biochemistry, Vol. 41, No. 33. (20 August 2002), pp. 10472-10481. by R. L. Mcfeeters, R. E. Oswald posted to dynamics ion_channels nmda nmr by LamBras on 2008-07-20 15:33:08 as
	Structure and Function of Glutamate Receptor Ion Channels [My Copy] Annual Review of Physiology, Vol. 66, No. 1. (2004), pp. 161-181. by Mark L. Mayer, Neali Armstrong posted to ion_channels nmda by LamBras on 2008-07-20 15:31:13 as along with 1 person mattions
	Crystal Structures of the GluR5 and GluR6 Ligand Binding Cores: Molecular Mechanisms Underlying Kainate Receptor Selectivity [My Copy] Neuron, Vol. 45, No. 4. (17 February 2005), pp. 539-552. by Mark L. Mayer posted to ion_channels nmda by LamBras on 2008-07-20 15:31:00 as

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flexibility	61
md	61
nmda	58
serinracemase	58
docking	53
virtual_screening	45
adme	30
drugdesign	26
review	19
scoring	18
cheminformatics	14
trna	13
bayesian	12
free_energy	12
ion_channels	12
muscarinic	12
sidechain	12
library_design	10
homology_modeling	9
normal_modes	8
targeted_md	8
nr1	7
rotamers	7
sar	7
conformers	6
gpcr	6
clustering	5
forcefield	5
nmr	5
xray	5
druglike	4
herg	4
proteins	4
surface	4
water_replacement	4
alzheimer	3
chemicalspace	3
ensemble	3
fingerprints	3
hts	3
scaffoldhopping	3
correlation	2
dynamics	2
graph	2
hd	2
lipophilicity	2
mmpbsa	2
pipelining	2
racemase	2
shape	2
similarity	2
allosteric	1
denovo	1
de_novo	1
induced_fit	1
itc	1
m1m2	1
ppb	1
qsar	1
r1	1
schroedinger	1
validation	1
virtuak_screening	1
x-ray	1

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