The internal structure of mitochondria Export

@article{Frey:2006a, abstract = {Electron microscopic (EM) tomography is providing important new insights into the internalorganization of mitochondria. The standard baffle model for cristae structure, called into question years ago, has now clearly been shown to be inaccurate. Depending on source and conformational state, cristae can vary from simple tubular structures to more complex lamellar structures merging with the inner boundary membrane through tubular structures 28 nm in diameter. The structural information provided by EM tomography has important implications for mitochondrial bioenergetics, biogenesis and the role of mitochondria in apoptosis. The structural paradigm defined by EM tomography is helping in the design of new experimental approaches to mitochondrial function.}, author = {Frey, Terrence G. and Mannella, Carmen A.}, citeulike-article-id = {776550}, journal = {Trends in Biochemical Sciences}, keywords = {bibtex-import, mitochondria}, local-url = {file://localhost/Users/hohensee/Documents/Papers/Frey/0The\%20internal\%20structure\%20of\%20mitochondria.pdf}, month = {July}, number = {7}, pages = {319--324}, posted-at = {2006-07-27 19:24:31}, priority = {2}, title = {The internal structure of mitochondria}, url = {http://www.sciencedirect.com.ezp1.harvard.edu/science?_ob=ArticleURL&_aset=V-WA-A-W-A-MsSWYWW-UUW-U-AAVDYEVUYB-AAVCVDVYYB-YUVEEEWYY-A-U&_rdoc=1&_fmt=summary&_udi=B6TCV-40NMPT1-4&_coverDate=07%2F01%2F2000&_cdi=5180&_orig=search&_st=13&_sort=d&view=c&_acct=C000014438&_version=1&_urlVersion=0&_userid=209690&md5=7acf981afdc08392948ba5aa4a7055d0}, volume = {25}, year = {2006} }

TY - JOUR ID - Frey:2006a L3 - citeulike-article-id:776550 N2 - Electron microscopic (EM) tomography is providing important new insights into the internalorganization of mitochondria. The standard baffle model for cristae structure, called into question years ago, has now clearly been shown to be inaccurate. Depending on source and conformational state, cristae can vary from simple tubular structures to more complex lamellar structures merging with the inner boundary membrane through tubular structures 28 nm in diameter. The structural information provided by EM tomography has important implications for mitochondrial bioenergetics, biogenesis and the role of mitochondria in apoptosis. The structural paradigm defined by EM tomography is helping in the design of new experimental approaches to mitochondrial function. IS - 7 JF - Trends in Biochemical Sciences EP - 324 TI - The internal structure of mitochondria VL - 25 SP - 319 KW - bibtex-import KW - mitochondria AU - Frey, Terrence AU - Mannella, Carmen PY - 2006/July// ER -