Infant pertussis: who was the source? Export

@article{citeulike:2173027, abstract = {BACKGROUND: In the United States in the 1990s, the incidence of reported pertussis in adults, adolescents and infants increased; infants younger than 1 year of age had the highest reported incidence. METHODS: In 4 states with Enhanced Pertussis Surveillance, we examined the epidemiology of reported pertussis cases to determine the source of pertussis among infants. A source was defined as a person with an acute cough illness who had contact with the case-infant 7-20 days before the infant's onset of cough. RESULTS: The average annual pertussis incidence per 100,000 infants younger than 1 year of age varied by state: 22.9 in Georgia; 42.1 in Illinois; 93.0 in Minnesota; and 35.8 in Massachusetts. Family members of 616 (80\%) of 774 reported case-infants were interviewed; a source was identified for 264 (43\%) of the 616 case-infants. Among the 264 case-infants, mothers were the source for 84 (32\%) and another family member was the source for 113 (43\%). Of the 219 source-persons with known age, 38 (17\%) were age 0-4 years, 16 (7\%) were age 5-9 years, 43 (20\%) were age 10-19 years, 45 (21\%) were age 20-29 years and 77 (35\%) were age > or =30 years. CONCLUSIONS: The variation in reported pertussis incidence in the 4 states might have resulted from differences in awareness of pertussis among health care providers, diagnostic capacity and case classification. Among case-infants with an identifiable source, family members (at any age) were the main source of pertussis. Understanding the source of pertussis transmission to infants may provide new approaches to prevent pertussis in the most vulnerable infants.}, address = {Bacterial Vaccine Preventable Diseases Branch, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA, USA.}, author = {Bisgard, K. M. and Pascual, F. B. and Ehresmann, K. R. and Miller, C. A. and Cianfrini, C. and Jennings, C. E. and Rebmann, C. A. and Gabel, J. and Schauer, S. L. and Lett, S. M.}, citeulike-article-id = {2173027}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/15545851}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=15545851}, issn = {0891-3668}, journal = {Pediatr Infect Dis J}, keywords = {bisgard, c, ca, ce, cianfrini, ehresmann, fb, gabel, infant, j, jennings, km, kr, lett, miller, pascual, pertussis, rebmann, schauer, sl, sm, source}, month = {November}, number = {11}, pages = {985--989}, posted-at = {2008-08-04 19:53:21}, priority = {3}, title = {Infant pertussis: who was the source?}, url = {http://view.ncbi.nlm.nih.gov/pubmed/15545851}, volume = {23}, year = {2004} }

TY - JOUR ID - citeulike:2173027 L3 - citeulike-article-id:2173027 N2 - BACKGROUND: In the United States in the 1990s, the incidence of reported pertussis in adults, adolescents and infants increased; infants younger than 1 year of age had the highest reported incidence. METHODS: In 4 states with Enhanced Pertussis Surveillance, we examined the epidemiology of reported pertussis cases to determine the source of pertussis among infants. A source was defined as a person with an acute cough illness who had contact with the case-infant 7-20 days before the infant's onset of cough. RESULTS: The average annual pertussis incidence per 100,000 infants younger than 1 year of age varied by state: 22.9 in Georgia; 42.1 in Illinois; 93.0 in Minnesota; and 35.8 in Massachusetts. Family members of 616 (80%) of 774 reported case-infants were interviewed; a source was identified for 264 (43%) of the 616 case-infants. Among the 264 case-infants, mothers were the source for 84 (32%) and another family member was the source for 113 (43%). Of the 219 source-persons with known age, 38 (17%) were age 0-4 years, 16 (7%) were age 5-9 years, 43 (20%) were age 10-19 years, 45 (21%) were age 20-29 years and 77 (35%) were age > or =30 years. CONCLUSIONS: The variation in reported pertussis incidence in the 4 states might have resulted from differences in awareness of pertussis among health care providers, diagnostic capacity and case classification. Among case-infants with an identifiable source, family members (at any age) were the main source of pertussis. Understanding the source of pertussis transmission to infants may provide new approaches to prevent pertussis in the most vulnerable infants. IS - 11 JF - Pediatr Infect Dis J SN - 0891-3668 AD - Bacterial Vaccine Preventable Diseases Branch, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA, USA. EP - 989 TI - Infant pertussis: who was the source? VL - 23 SP - 985 KW - bisgard KW - c KW - ca KW - ce KW - cianfrini KW - ehresmann KW - fb KW - gabel KW - infant KW - j KW - jennings KW - km KW - kr KW - lett KW - miller KW - pascual KW - pertussis KW - rebmann KW - schauer KW - sl KW - sm KW - source AU - Bisgard, KM AU - Pascual, FB AU - Ehresmann, KR AU - Miller, CA AU - Cianfrini, C AU - Jennings, CE AU - Rebmann, CA AU - Gabel, J AU - Schauer, SL AU - Lett, SM PY - 2004/11// UR - http://view.ncbi.nlm.nih.gov/pubmed/15545851 ER -