Predicted structure of the bovine calcitonin gene-related peptide and the carboxy-terminal flanking peptide of bovine calcitonin precursor. Export

@article{citeulike:1132832, abstract = {We have isolated from a bovine genomic library a clone which contains the calcitonin (CT) and CT gene-related peptide (CGRP) sequences, using probes representing the human CT and CGRP sequences. Sequence analysis has identified the nucleotide sequence coding for bovine CT, its C-terminal flanking peptide and bovine CGRP. The deduced amino acid sequence of bovine CGRP revealed a significant homology with other CGRPs so far reported. It differs by only one amino acid from rat CGRP alpha and porcine CGRP, and by three and four amino acids from human CGRP beta and alpha respectively. Bovine CT has, however, only 14 out of 32 residues in common with human CT. As in the human CT precursor, the C-terminal flanking peptide of bovine CT precursor is a 21 amino acid peptide. It shares only 11 residues in common with its human counterpart. This study thus provides further evidence that CGRP, in contrast to CT and its C-terminal flanking peptide, is a highly conserved molecule.}, address = {Department of Chemical Pathology, Royal Postgraduate Medical School, London.}, author = {Collyear, K. and Girgis, S. I. and Saunders, G. and MacIntyre, I. and Holt, G.}, citeulike-article-id = {1132832}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/2043242}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=2043242}, comment = {CGRP文献ファイル}, issn = {0952-5041}, journal = {J Mol Endocrinol}, keywords = {bovine, cgrp}, month = {April}, number = {2}, pages = {147--152}, posted-at = {2007-03-01 02:16:45}, priority = {2}, title = {Predicted structure of the bovine calcitonin gene-related peptide and the carboxy-terminal flanking peptide of bovine calcitonin precursor.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/2043242}, volume = {6}, year = {1991} }

TY - JOUR ID - citeulike:1132832 L3 - citeulike-article-id:1132832 N2 - We have isolated from a bovine genomic library a clone which contains the calcitonin (CT) and CT gene-related peptide (CGRP) sequences, using probes representing the human CT and CGRP sequences. Sequence analysis has identified the nucleotide sequence coding for bovine CT, its C-terminal flanking peptide and bovine CGRP. The deduced amino acid sequence of bovine CGRP revealed a significant homology with other CGRPs so far reported. It differs by only one amino acid from rat CGRP alpha and porcine CGRP, and by three and four amino acids from human CGRP beta and alpha respectively. Bovine CT has, however, only 14 out of 32 residues in common with human CT. As in the human CT precursor, the C-terminal flanking peptide of bovine CT precursor is a 21 amino acid peptide. It shares only 11 residues in common with its human counterpart. This study thus provides further evidence that CGRP, in contrast to CT and its C-terminal flanking peptide, is a highly conserved molecule. IS - 2 JF - J Mol Endocrinol SN - 0952-5041 AD - Department of Chemical Pathology, Royal Postgraduate Medical School, London. EP - 152 TI - Predicted structure of the bovine calcitonin gene-related peptide and the carboxy-terminal flanking peptide of bovine calcitonin precursor. VL - 6 SP - 147 KW - bovine KW - cgrp N1 - CGRP文献ファイル AU - Collyear, K AU - Girgis, SI AU - Saunders, G AU - MacIntyre, I AU - Holt, G PY - 1991/04// UR - http://view.ncbi.nlm.nih.gov/pubmed/2043242 ER -