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Factors that influence characteristics of genetic biobanks. Export

Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing / Sigma Theta Tau, Vol. 39, No. 1. (2007), pp. 25-29.

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attitudes biobanks demographics genetic-research participants

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PURPOSE: To identify demographic differences between patients who choose participation and patients who choose nonparticipation in genetic biobanks, and to explore reasons for nonparticipation. DESIGN: Prospective study of hospitalized cardiovascular patients approached to participate in a genetic biobank, 300 nonparticipants and 299 participants, in the southwestern US. METHODS: Reasons for nonparticipation were explored. Logistic regression was performed to determine if gender, race or ethnicity, or age predicted nonparticipation. FINDINGS: Race or ethnicity and age were significantly different between participants and nonparticipants, but gender was not. Blood-sample collection was the main reason for declining participation. CONCLUSIONS: Minority and older adults were less likely to participate. Understanding reasons for nonparticipation in this group might aid in the development of methods used to obtain a diverse population in biobanks.


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