Glycemic index and heart disease Export

@article{citeulike:2744307, abstract = {A diet high in carbohydrates with high glycemic indexes (GI) and glycemic load were linked to risk of coronary heart disease development in women in a large prospective study. Two cross-sectional studies showed that low-GI diets are associated with high HDL-cholesterol concentrations, especially in women. In a tightly controlled study of patients with type 2 diabetes, serum total cholesterol, LDL cholesterol, and apolipoprotein B concentrations fell more significantly after a low-GI diet than after a high-GI diet. In the same study, plasminogen activator inhibitor-1 concentrations were reduced by 58\% after the low-GI diet. Insulin-stimulated glucose uptake by adipocytes was significantly higher in patients undergoing coronary artery bypass graft surgery after 4 wk of consuming a low-GI diet than after consuming a high-GI diet. The effects of low-GI diets may be mediated by changes in postprandial fatty acid concentrations or by hormonal signals from adipocytes, but a possible association of low-GI diets with some other dietary factor such as chromium must not be excluded. Proof of the clinical value of low-GI diets awaits prospective trials, which should include short-term observations covering periods of metabolic stress induced by surgery as well as long-term trials with clinical endpoints.}, author = {Leeds, Anthony R.}, citeulike-article-id = {2744307}, citeulike-linkout-0 = {http://www.ajcn.org/cgi/content/abstract/76/1/286S}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/12081853}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=12081853}, day = {1}, journal = {Am J Clin Nutr}, keywords = {glucose\_uptake, glycemic\_index, glycemic\_load, heart\_disease, higea}, month = {July}, number = {1}, pages = {286S--289}, posted-at = {2008-05-02 08:17:44}, priority = {2}, title = {Glycemic index and heart disease}, url = {http://www.ajcn.org/cgi/content/abstract/76/1/286S}, volume = {76}, year = {2002} }

TY - JOUR ID - citeulike:2744307 L3 - citeulike-article-id:2744307 N2 - A diet high in carbohydrates with high glycemic indexes (GI) and glycemic load were linked to risk of coronary heart disease development in women in a large prospective study. Two cross-sectional studies showed that low-GI diets are associated with high HDL-cholesterol concentrations, especially in women. In a tightly controlled study of patients with type 2 diabetes, serum total cholesterol, LDL cholesterol, and apolipoprotein B concentrations fell more significantly after a low-GI diet than after a high-GI diet. In the same study, plasminogen activator inhibitor-1 concentrations were reduced by 58% after the low-GI diet. Insulin-stimulated glucose uptake by adipocytes was significantly higher in patients undergoing coronary artery bypass graft surgery after 4 wk of consuming a low-GI diet than after consuming a high-GI diet. The effects of low-GI diets may be mediated by changes in postprandial fatty acid concentrations or by hormonal signals from adipocytes, but a possible association of low-GI diets with some other dietary factor such as chromium must not be excluded. Proof of the clinical value of low-GI diets awaits prospective trials, which should include short-term observations covering periods of metabolic stress induced by surgery as well as long-term trials with clinical endpoints. IS - 1 JF - Am J Clin Nutr EP - 289 TI - Glycemic index and heart disease VL - 76 SP - 286S KW - glucose_uptake KW - glycemic_index KW - glycemic_load KW - heart_disease KW - higea AU - Leeds, Anthony PY - 2002/07/01/ UR - http://www.ajcn.org/cgi/content/abstract/76/1/286S ER -