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statistical	309
evidence-based-medicine	308
meta-analysis	305
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models	196
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evidence-based-medicine---criticism	55
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risk-assessment	45
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computer-simulation	43
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confounding-factors-epidemiology	42
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logistic-models	41
predictive-value-of-tests	41
publication-bias---methods	40
economic-analysis	40
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updating-systematic-reviews	39
random-allocation	39
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periodicals-as-topic	30
analysis-of-variance	30
drug-industry	30
case-control-studies	29
pregnancy	29
information-storage-and-retrieval--methods	29
quality-assessment-of-ccts	29
noninferiority	29
direct-vs-indirect-comparisons	29
epidemiologic-methods	29
likelihood-functions	29
prognosis	28
practice-guidelines-as-topic	28
organizational	28
consort	28
fda	28
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prognosis-studies	27
rating-a-body-of-evidence	27
conflict-of-interest	26
monte-carlo-method	26
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probability	26
diagnosis	26
bayesian-meta-analysis	26
guidelines-as-topic	25
retrospective-studies	25
prospective-studies	25
non-phs	25
internet	25
information-storage-and-retrieval	24
genetic	24
editorial-policies	24
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questionnaires	24
patient-communication	23
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clinical-medicine	23
personalized-medicine	23
randomized-controlled-trials-sn-statistics-numerical-data	22
adolescent	22
quality-of-health-care	22
periodicals-as-topic--standards	22
clinical-trials-st-standards	22
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proportional-hazards-models	21
epidemiologic-research-design	20
research-design-standards	20
clinical-competence	20
evidence-based-medicine--methods	20
education	20
evaluation-studies-as-topic	19
language	19
publishing--standards	19
double-blind-method	19
study-design	19
clinical-trials-mt-methods	19
non-randomized-study-designs	19
methods	18
quality-adjusted-life-years	18
individual-patient-data-meta-analysis	18
diffusion-of-innovation	18
attitude-of-health-personnel	18
routine--standards	18
infant	18
observation	18
formularies	18
information-dissemination	17
multivariate-analysis	17
genetics	17
public-health	17
physicians-practice-patterns	17
classic	17
number-needed-to-treat	17
case-reports-case-series	17
follow-up-studies	17
observer-variation	17
clinical	17
epidemiologic-studies	17
biomedical	16
theoretical	16
reference-standards	16
registries	16
drug-therapy	16
heterogeneity	16
uncertainty	16
genetic-predisposition-to-disease	16
biometry	16
statistics-as-topic	16
effect-modifiers-epidemiology	16
racial-and-ethnic-differences	16
quality-of-life	16
evaluation-studies	16
randomized-controlled-trials-as-topic--standards	16
observational-study-designs---propensity-scores	16
clinical-trials-sn-statistics-numerical-data	15
randomized-controlled-trials---novel-design	15
effect-measures	15
evidence-based-medicine-mt-methods	15
practice	15
anti-inflammatory-agents	15
medical-informatics-applications	15
periodicals-st-standards	14
presenting-results	14
software	14
terminology	14
guideline-adherence	14
bayesian-statistics	14
blinding	14
health-promotion	14
physician-patient-relations	14
health-services	14
united-states-food-and-drug-administration	14
evidence-based-medicine-st-standards	14
epidemiology	14
health-priorities	14
subject-headings	14
terminology-as-topic	14
pubmed	13
data-collection-mt-methods	13
myocardial-infarction-dt-drug-therapy	13
societies	13
patient-satisfaction	13
safety	13
attitude-to-health	13
priority-setting---research	13
practice-guidelines-st-standards	13
journalism	13
combining-studies-of-mixed-design	13
practice-guidelines-as-topic--standards	12
ontario	12
physicians	12
health-services-research-mt-methods	12
family-practice	12
review	12
allocation-concealment	12
mass-screening	12
placebo-conrolled-trials	12
evidence-based-medicine-es-ethics	12
medical-subject-headings	12
causality	12
grey-literature	12
critical-appraisal	12
therapeutics	12
newborn	12
linear-models	12
drug	12
animal-studies	12
false-positive-reactions	12
routine	12
prevalence	12
research-st-standards	11
polymorphism	11
intervention-studies	11
knowledge	11
communication	11
clinical-protocols	11
forecasting	11
health	11
genotype	11
advisory-committees	11
information-storage-and-retrieval-mt-methods	11
research-support-as-topic	11
diagnostic-techniques-and-procedures--standards	11
animals	11
statistics-mt-methods	11
publishing-standards	11
personalizedmedicine	11
variation-in-methods-for-systematic-reviews	11
outcome-and-process-assessment-health-care	11
decision-trees	11
health-behavior	10
information-systems	10
surgery	10
incidence	10
evidence-based-medicine--standards	10
attitudes	10
authorship	10
abstracting-and-indexing-as-topic	10
health-knowledge	10
reviews-of-systematic-reviews	10
efficiency	9
clinical-trials-as-topic--standards	9
arthritis	9
patient-compliance	9
product-surveillance	9
patient-participation	9
biomedical-research--methods	9
carcinoma	9
health-care-rationing	9
diagnostic-techniques-and-procedures	9
placebos	9
problem-formulation	9
aged---80-and-over	9
clinical-trials-as-topic--methods	9
guideline	9
writing	9
tomography	9
united-states-agency-for-healthcare-research-and-quality	9
biometry--methods	9
severity-of-illness-index	9
econometric	9
consensus	9
user-computer-interface	9
acute-disease	9
informed-consent	9
nonparametric	9
meta-regression	9
cluster-analysis	9
cross-sectional-studies	8
propensity-score	8
empirical-evidence-of-bias	8
comparative-effectiveness-research	8
abstracting-and-indexing	8
mortality	8
libraries	8
dose-response-relationship	8
guidelines-as-topic--standards	8
diagnostic-errors	8
preschool	8
randomized-controlled-trials---sn-statistics-numerical-data	8
drug-evaluation	8
england	8
individual-patient-meta-analysis	8
markov-chains	8
clinical-trials-methods	8
randomized-controlled-trials-as-topic--methods	8
economics	8
adverse-drug-reaction-reporting-systems	8
philosophy	8
insurance-coverage	8
nice	8
biomedical--methods	8
randomized-controlled-trials-standards	8
international-cooperation	8
publishing-sn-statistics-numerical-data	8
clinical-trials-as-topic--statistics-numerical-data	8
information-services	8
reporting-bias	7
genetic-markers	7
data-presentation	7
evidence-based-medicine-td-trends	7
patient-acceptance-of-health-care	7
hm-method	7
ethics-committees	7
program-evaluation	7
randomized-controlled-trials-as-topic--statistics-numerical-data	7
derp	7
evidence-based-medicine-ec-economics	7
disclosure	7
magnetic-resonance-imaging	7
congresses-as-topic	7
health-care-costs	7
costs-and-cost-analysis	7
sampling-studies	7
delivery-of-health-care	7
psychological	7
program-evaluation-mt-methods	7
searching---medline	7
evidence-based-medicine---complementary	7
genome	7
genetic-screening	7
single-blind-method	7
drug-industry-ec-economics	7
continuing	7
mutation	7
age-factors	7
information-storage-and-retrieval-methods	7
empirical-research	7
culture	7
expert-opinion	7
diabetes-mellitus	7
hypertension-dt-drug-therapy	7
biological	7
research-design-sn-statistics-numerical-data	7
tumor-markers	7
europe	7
quality-indicators	6
therapeutic-equivalency	6
resource-allocation	6
financing	6
phenotype	6
state-medicine	6
adrenergic-beta-antagonists-tu-therapeutic-use	6
extramural	6
judgment	6
scientific-misconduct	6
publishing--statistics-numerical-data	6
randomized-controlled-trials-as-topic-standards	6
large-trials	6
choice-behavior	6
genes	6
evidence-based-practice	6
periodicals-as-topic-standards	6
data-collection-st-standards	6
80-and-over	6
research-design---st-standards	6
drug-approval	6
internationality	6
least-squares-analysis	6
rare-or-zero-events	6
biomedical-mt-methods	6
systematic-reviews---updating	6
disease-free-survival	6
angioplasty	6
access-to-information	6
preventive-health-services-ec-economics	6
randomized-controlled-trials-statistics-numerical-data	6
outcome-assessment-health-care-methods	6
statistics-methods	6
publication-bias---stopping-trials	6
fibrinolytic-agents-tu-therapeutic-use	6
medicare	6
survival-rate	6
treatment	6
consumer-participation	6
cooperative-behavior	6
antidepressive-agents--therapeutic-use	6
sex-factors	6
standards	6
chronic-disease	6
nih	6
false-negative-reactions	6
professional-practice	6
cost-of-illness	6
electrocardiography	5
medline-st-standards	5
insufficient-evidence	5
physicians-practice-patterns---st-standards	5
delphi-technique	5
decision-support-systems	5
medical--standards	5
death	5
information	5
national-library-of-medicine-us	5
receptors	5
treatment-failure	5
administration---oral	5
publishing---st-standards	5
history---20th-century	5
journal-impact-factor	5
publication-bias--statistics-numerical-data	5
influenza	5
cochrane-methods-newsletter	5
socioeconomic-factors	5
quality-assessment-of-systematic-reviews	5
pharmaceutical-preparations---ae-adverse-effects	5
politics	5
cause-of-death	5
randomized-controlled-trials---st-standards	5
research-mt-methods	5
therapeutic-use	5
cmra3	5
usgovt	5
surgical-procedures	5
biomedical-research--standards	5
preventive-health-services-mt-methods	5
drug-therapy-adverse-effects	5
myocardial-infarction	5
clinical-trials-ec-economics	5
genetic-diseases	5
orthopedics	5
myocardial-infarction-mo-mortality	5
prescriptions	5
practice-guidelines---st-standards	5
statistics-as-topic--methods	5
benchmarking	5
abstracting-and-indexing-as-topic--standards	5
pharmaceutical	5
clinical-trials---sn-statistics-numerical-data	5
quality	5
germany	5
diet	5
antibodies	5
pilot-projects	5
quorum	5
complementary-therapies	5
evidence-based-medicine---mt-methods	5