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A DNA computing inspired computational model Export

Theor. Comput. Sci., Vol. 404, No. 1-2. (2008), pp. 88-96.

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biocomputing computational-models computing-models dna-computing membrane-computing membranes models-of-computation rewriting-systems synthetic-biology universal-rewriting

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In this paper we propose a universal rewriting system whose computational steps closely resemble the manner in which nature computes double stranded DNA molecules. The basic data structure is given by a couple of strings paired by a complementarity relation (such as the Watson-Crick one), and the rewriting rules have a biotechnological implementation as DNA computing standard procedures. The antiparallel orientation of the formal strings laying on the double structure is taken into consideration, as in [G. Franco, V. Manca, An algorithmic analysis of DNA structure, Soft Computing-A Fusion of Foundations, Methodologies and Applications 9 (10) (2005) 761-768] it was shown to be essential for some informational and computational aspects underlying the DNA autoduplication process. The universality of such a system has been proved and the biotechnological details of a possible implementation have been outlined. Moreover, the membrane system which turned out to be the natural context to describe our system in [G. Franco, M. Margenstern, Computing by Floating Strings, in: N. Busi, C. Zandron (Eds.), Proceedings of the First Workshop on Membrane Computing and Biologically Inspired Process Calculi (MeCBIC 2006), July 9, S. Servolo, Venice, Italy, in: ENTCS, vol. 171(issue 2), July 2007, pp. 95-104] has been proposed here in more technical detail, and the announced extension work has been developed.


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