Evolution of innate and adaptive immunity: can we draw a line? Export

@article{citeulike:2838352, abstract = {Several recent findings in the field of comparative immunology have reinforced the importance of examining the molecular and functional features of immune systems in a variety of organisms. Particularly exciting are the discoveries of a new gene rearrangement mechanism in lampreys and a somatic diversification of mollusk immune genes. These immune features being found in animals previously believed only to have innate immunity, as well as the flood of information on immune genes, molecules and mechanisms in many different creatures, have prompted us to revisit the artificial dichotomy between adaptive and innate immune systems. Although we draw no startling conclusions, we hope to encourage different thought patterns when viewing immune systems.}, address = {Department of Microbiology and Immunology, University of Maryland at Baltimore School of Medicine, Baltimore, MD 21201-1559, USA. MFlajnik@som.umaryland.edu}, author = {Flajnik, M. F. and Du Pasquier, L.}, citeulike-article-id = {2838352}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.it.2004.10.001}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/15530832}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=15530832}, doi = {10.1016/j.it.2004.10.001}, issn = {1471-4906}, journal = {Trends in immunology}, keywords = {conceptual, evolution}, month = {December}, number = {12}, pages = {640--644}, posted-at = {2009-05-17 15:08:23}, priority = {2}, title = {Evolution of innate and adaptive immunity: can we draw a line?}, url = {http://dx.doi.org/10.1016/j.it.2004.10.001}, volume = {25}, year = {2004} }

TY - JOUR ID - citeulike:2838352 L3 - citeulike-article-id:2838352 N2 - Several recent findings in the field of comparative immunology have reinforced the importance of examining the molecular and functional features of immune systems in a variety of organisms. Particularly exciting are the discoveries of a new gene rearrangement mechanism in lampreys and a somatic diversification of mollusk immune genes. These immune features being found in animals previously believed only to have innate immunity, as well as the flood of information on immune genes, molecules and mechanisms in many different creatures, have prompted us to revisit the artificial dichotomy between adaptive and innate immune systems. Although we draw no startling conclusions, we hope to encourage different thought patterns when viewing immune systems. IS - 12 JF - Trends in immunology SN - 1471-4906 AD - Department of Microbiology and Immunology, University of Maryland at Baltimore School of Medicine, Baltimore, MD 21201-1559, USA. MFlajnik@som.umaryland.edu EP - 644 TI - Evolution of innate and adaptive immunity: can we draw a line? VL - 25 SP - 640 KW - conceptual KW - evolution AU - Flajnik, MF AU - Du Pasquier, L PY - 2004/12// UR - http://dx.doi.org/10.1016/j.it.2004.10.001 ER -