Genomic location analysis by ChIP-Seq Export

@article{citeulike:3981553, abstract = {The interaction of a multitude of transcription factors and other chromatin proteins with the genome can influence gene expression and subsequently cell differentiation and function. Thus systematic identification of binding targets of transcription factors is key to unraveling gene regulation networks. The recent development of ChIP-Seq has revolutionized mapping of DNA-protein interactions. Now protein binding can be mapped in a truly genome-wide manner with extremely high resolution. This review discusses ChIP-Seq technology, its possible pitfalls, data analysis and several early applications. J. Cell. Biochem. 107: 11-18, 2009. {\copyright} 2009 Wiley-Liss, Inc.}, address = {Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, NIH, Bethesda, MD 20892}, author = {Barski, Artem and Zhao, Keji}, citeulike-article-id = {3981553}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/jcb.22077}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19173299}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19173299}, citeulike-linkout-3 = {http://www3.interscience.wiley.com/cgi-bin/abstract/121663153/ABSTRACT}, day = {1}, doi = {10.1002/jcb.22077}, issn = {1097-4644}, journal = {Journal of Cellular Biochemistry}, keywords = {analysis, chip-sequence, dna, sequence, transcription\_factors}, month = {May}, number = {1}, pages = {11--18}, posted-at = {2009-11-05 16:51:21}, priority = {2}, title = {Genomic location analysis by ChIP-Seq}, url = {http://dx.doi.org/10.1002/jcb.22077}, volume = {107}, year = {2009} }

TY - JOUR ID - citeulike:3981553 L3 - citeulike-article-id:3981553 N2 - The interaction of a multitude of transcription factors and other chromatin proteins with the genome can influence gene expression and subsequently cell differentiation and function. Thus systematic identification of binding targets of transcription factors is key to unraveling gene regulation networks. The recent development of ChIP-Seq has revolutionized mapping of DNA-protein interactions. Now protein binding can be mapped in a truly genome-wide manner with extremely high resolution. This review discusses ChIP-Seq technology, its possible pitfalls, data analysis and several early applications. J. Cell. Biochem. 107: 11-18, 2009. © 2009 Wiley-Liss, Inc. IS - 1 JF - Journal of Cellular Biochemistry SN - 1097-4644 AD - Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, NIH, Bethesda, MD 20892 EP - 18 TI - Genomic location analysis by ChIP-Seq VL - 107 SP - 11 KW - analysis KW - chip-sequence KW - dna KW - sequence KW - transcription_factors AU - Barski, Artem AU - Zhao, Keji PY - 2009/05/01/ UR - http://dx.doi.org/10.1002/jcb.22077 ER -