Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels. Export

@article{citeulike:3773928, abstract = {The ability to generate microorganisms that can produce biofuels similar to petroleum-based transportation fuels would allow the use of existing engines and infrastructure and would save an enormous amount of capital required for replacing the current infrastructure to accommodate biofuels that have properties significantly different from petroleum-based fuels. Several groups have demonstrated the feasibility of manipulating microbes to produce molecules similar to petroleum-derived products, albeit at relatively low productivity (e.g. maximum butanol production is around 20 g/L). For cost-effective production of biofuels, the fuel-producing hosts and pathways must be engineered and optimized. Advances in metabolic engineering and synthetic biology will provide new tools for metabolic engineers to better understand how to rewire the cell in order to create the desired phenotypes for the production of economically viable biofuels.}, author = {Lee, Sung Kuk K. and Chou, Howard and Ham, Timothy S. and Lee, Taek Soon S. and Keasling, Jay D.}, citeulike-article-id = {3773928}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.copbio.2008.10.014}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0958166908001420}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/18996194}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=18996194}, doi = {10.1016/j.copbio.2008.10.014}, issn = {1879-0429}, journal = {Current opinion in biotechnology}, keywords = {bacteria, biofuels, biology, butanol, engineering, ethanol, from, fuels, metabolic, microorganisms, production, review, synthetic}, month = {December}, number = {6}, pages = {556--563}, posted-at = {2009-07-02 09:36:44}, priority = {2}, title = {Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels.}, url = {http://dx.doi.org/10.1016/j.copbio.2008.10.014}, volume = {19}, year = {2008} }

TY - JOUR ID - citeulike:3773928 L3 - citeulike-article-id:3773928 N2 - The ability to generate microorganisms that can produce biofuels similar to petroleum-based transportation fuels would allow the use of existing engines and infrastructure and would save an enormous amount of capital required for replacing the current infrastructure to accommodate biofuels that have properties significantly different from petroleum-based fuels. Several groups have demonstrated the feasibility of manipulating microbes to produce molecules similar to petroleum-derived products, albeit at relatively low productivity (e.g. maximum butanol production is around 20 g/L). For cost-effective production of biofuels, the fuel-producing hosts and pathways must be engineered and optimized. Advances in metabolic engineering and synthetic biology will provide new tools for metabolic engineers to better understand how to rewire the cell in order to create the desired phenotypes for the production of economically viable biofuels. IS - 6 JF - Current opinion in biotechnology SN - 1879-0429 EP - 563 TI - Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels. VL - 19 SP - 556 KW - bacteria KW - biofuels KW - biology KW - butanol KW - engineering KW - ethanol KW - from KW - fuels KW - metabolic KW - microorganisms KW - production KW - review KW - synthetic AU - Lee, Sung Kuk AU - Chou, Howard AU - Ham, Timothy AU - Lee, Taek Soon AU - Keasling, Jay PY - 2008/12// UR - http://dx.doi.org/10.1016/j.copbio.2008.10.014 ER -