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Regulation of coenzyme A transferase and acetoacetate decarboxylase activities in Clostridium acetobutylicum. Export

Annales de l'Institut Pasteur. Microbiology, Vol. 139, No. 6. (c 1988), pp. 683-688.

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a acetoacetate acetobutylicum clostridium coenzyme decarboxylase regulation transferase

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The activity of two enzymes involved in acetone production in Clostridium acetobutylicum, acetoacetate decarboxylase and coenzyme A transferase, was studied under acidogenic or solventogenic conditions. Acetoacetate decarboxylase activity was low under acidogenic conditions and after pyruvate addition. Under the same conditions, coenzyme A transferase activity was high. A mutant which lacked acetoacetate decarboxylase activity but was positive for coenzyme A transferase activity was isolated.


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