A model for signal transduction during quorum sensing in Vibrio harveyi. Export

@article{citeulike:6014739, abstract = {We present a framework for analyzing luminescence regulation during quorum sensing in the bioluminescent bacterium Vibrio harveyi. Using a simplified model for signal transduction in the quorum sensing pathway, we identify key dimensionless parameters that control the system's response. These parameters are estimated using experimental data on luminescence phenotypes for different mutant strains. The corresponding model predictions are consistent with results from other experiments which did not serve as input for determining model parameters. Furthermore, the proposed framework leads to novel testable predictions for luminescence phenotypes and for responses of the network to different perturbations.}, author = {Banik, Suman K. and Fenley, Andrew T. and Kulkarni, Rahul V.}, citeulike-article-id = {6014739}, citeulike-linkout-0 = {http://dx.doi.org/10.1088/1478-3975/6/4/046008}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19843985}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19843985}, doi = {10.1088/1478-3975/6/4/046008}, issn = {1478-3975}, journal = {Physical biology}, keywords = {ai-2, harveyi, luxs, model, quorum, sensing, signal, transduction, vibrio}, number = {4}, posted-at = {2009-10-27 09:06:29}, priority = {2}, title = {A model for signal transduction during quorum sensing in Vibrio harveyi.}, url = {http://dx.doi.org/10.1088/1478-3975/6/4/046008}, volume = {6}, year = {2009} }

TY - JOUR ID - citeulike:6014739 L3 - citeulike-article-id:6014739 N2 - We present a framework for analyzing luminescence regulation during quorum sensing in the bioluminescent bacterium Vibrio harveyi. Using a simplified model for signal transduction in the quorum sensing pathway, we identify key dimensionless parameters that control the system's response. These parameters are estimated using experimental data on luminescence phenotypes for different mutant strains. The corresponding model predictions are consistent with results from other experiments which did not serve as input for determining model parameters. Furthermore, the proposed framework leads to novel testable predictions for luminescence phenotypes and for responses of the network to different perturbations. IS - 4 JF - Physical biology SN - 1478-3975 TI - A model for signal transduction during quorum sensing in Vibrio harveyi. VL - 6 KW - ai-2 KW - harveyi KW - luxs KW - model KW - quorum KW - sensing KW - signal KW - transduction KW - vibrio AU - Banik, Suman AU - Fenley, Andrew AU - Kulkarni, Rahul PY - 2009/// UR - http://dx.doi.org/10.1088/1478-3975/6/4/046008 ER -