ATP plays a role in neurite stimulation with activated mast cells. Export

@article{citeulike:2614719, abstract = {Previously, we showed that nerve-mast cell cross-talk can occur bidirectionally and that substance P is a mediator to activate mast cells. Here, we have studied the mediators to activate nerves cocultured with mast cells. Addition of antigen to the cocultures of superior cervical ganglia (SCG) and rat basophilic leukemia cells (RBLs) elicited Ca(2+) response in RBLs and after a lag period induced Ca(2+) signal in SCG neurites. Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid (purinergic receptor antagonist) or apyrase (ATP-hydrolyzing enzyme) reduced the Ca(2+) signals in neurites, indicating that ATP released from activated mast cells was one of important mediators to activate nerves.}, address = {Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.}, author = {Suzuki, R. and Furuno, T. and Okamoto, K. and Teshima, R. and Nakanishi, M.}, citeulike-article-id = {2614719}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.jneuroim.2007.09.013}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/17928071}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=17928071}, doi = {10.1016/j.jneuroim.2007.09.013}, issn = {0165-5728}, journal = {J Neuroimmunol}, keywords = {atp, endnote, mast, ngf}, month = {December}, number = {1-2}, pages = {49--56}, posted-at = {2008-03-31 03:32:22}, priority = {2}, title = {ATP plays a role in neurite stimulation with activated mast cells.}, url = {http://dx.doi.org/10.1016/j.jneuroim.2007.09.013}, volume = {192}, year = {2007} }

TY - JOUR ID - citeulike:2614719 L3 - citeulike-article-id:2614719 N2 - Previously, we showed that nerve-mast cell cross-talk can occur bidirectionally and that substance P is a mediator to activate mast cells. Here, we have studied the mediators to activate nerves cocultured with mast cells. Addition of antigen to the cocultures of superior cervical ganglia (SCG) and rat basophilic leukemia cells (RBLs) elicited Ca(2+) response in RBLs and after a lag period induced Ca(2+) signal in SCG neurites. Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid (purinergic receptor antagonist) or apyrase (ATP-hydrolyzing enzyme) reduced the Ca(2+) signals in neurites, indicating that ATP released from activated mast cells was one of important mediators to activate nerves. IS - 1-2 JF - J Neuroimmunol SN - 0165-5728 AD - Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan. EP - 56 TI - ATP plays a role in neurite stimulation with activated mast cells. VL - 192 SP - 49 KW - atp KW - endnote KW - mast KW - ngf AU - Suzuki, R AU - Furuno, T AU - Okamoto, K AU - Teshima, R AU - Nakanishi, M PY - 2007/12// UR - http://dx.doi.org/10.1016/j.jneuroim.2007.09.013 ER -