Advanced glycation end products and cardiovascular disease. Export

@article{citeulike:2800684, abstract = {Cardiovascular disease (CVD) is the leading cause of mortality worldwide. Advanced glycation end products [AGEs] seem to play an important role for the development and/or progression of CVD mainly through induction of oxidative stress and inflammation. AGEs are a heterogenous group of molecules formed by the nonenzymatic reaction of reducing sugars with amino acids of proteins, lipids and nucleic acids. Recent studies suggest that in addition to those endogenously formed, diet constitutes an important exogenous source of AGEs. Diet-derived AGEs contribute to the whole body AGE pool and the AGE-related pathology. Recent in vitro and in vivo studies revealed significant correlations between diet-derived AGEs and several risk factors and/or markers of CVD, suggesting the dietary AGEs restriction as a promising therapeutic intervention.}, address = {Endocrine Unit, 2nd Department of Internal Medicine-Propaedeutic, Research Institute and Diabetes Center, Attikon University Hospital, Athens, Greece, moly6592@yahoo.com.}, author = {Peppa, M. and Raptis, S. A.}, citeulike-article-id = {2800684}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/18473756}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=18473756}, issn = {1573-3998}, journal = {Current diabetes reviews}, keywords = {age, atherosclerosis}, month = {May}, number = {2}, pages = {92--100}, posted-at = {2008-05-15 05:46:06}, priority = {2}, title = {Advanced glycation end products and cardiovascular disease.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/18473756}, volume = {4}, year = {2008} }

TY - JOUR ID - citeulike:2800684 L3 - citeulike-article-id:2800684 N2 - Cardiovascular disease (CVD) is the leading cause of mortality worldwide. Advanced glycation end products [AGEs] seem to play an important role for the development and/or progression of CVD mainly through induction of oxidative stress and inflammation. AGEs are a heterogenous group of molecules formed by the nonenzymatic reaction of reducing sugars with amino acids of proteins, lipids and nucleic acids. Recent studies suggest that in addition to those endogenously formed, diet constitutes an important exogenous source of AGEs. Diet-derived AGEs contribute to the whole body AGE pool and the AGE-related pathology. Recent in vitro and in vivo studies revealed significant correlations between diet-derived AGEs and several risk factors and/or markers of CVD, suggesting the dietary AGEs restriction as a promising therapeutic intervention. IS - 2 JF - Current diabetes reviews SN - 1573-3998 AD - Endocrine Unit, 2nd Department of Internal Medicine-Propaedeutic, Research Institute and Diabetes Center, Attikon University Hospital, Athens, Greece, moly6592@yahoo.com. EP - 100 TI - Advanced glycation end products and cardiovascular disease. VL - 4 SP - 92 KW - age KW - atherosclerosis AU - Peppa, M AU - Raptis, SA PY - 2008/05// UR - http://view.ncbi.nlm.nih.gov/pubmed/18473756 ER -