Transcriptional control of human p53-regulated genes. Export

@article{citeulike:2713555, abstract = {The p53 protein regulates the transcription of many different genes in response to a wide variety of stress signals. Following DNA damage, p53 regulates key processes, including DNA repair, cell-cycle arrest, senescence and apoptosis, in order to suppress cancer. This Analysis article provides an overview of the current knowledge of p53-regulated genes in these pathways and others, and the mechanisms of their regulation. In addition, we present the most comprehensive list so far of human p53-regulated genes and their experimentally validated, functional binding sites that confer p53 regulation.}, author = {Riley, Todd and Sontag, Eduardo and Chen, Patricia and Levine, Arnold}, citeulike-article-id = {2713555}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nrm2395}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nrm2395}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/18431400}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=18431400}, doi = {10.1038/nrm2395}, issn = {1471-0080}, journal = {Nature reviews. Molecular cell biology}, keywords = {p53, review}, month = {May}, number = {5}, pages = {402--412}, posted-at = {2008-08-21 09:16:25}, priority = {2}, publisher = {Nature Publishing Group}, title = {Transcriptional control of human p53-regulated genes.}, url = {http://dx.doi.org/10.1038/nrm2395}, volume = {9}, year = {2008} }

TY - JOUR ID - citeulike:2713555 L3 - citeulike-article-id:2713555 N2 - The p53 protein regulates the transcription of many different genes in response to a wide variety of stress signals. Following DNA damage, p53 regulates key processes, including DNA repair, cell-cycle arrest, senescence and apoptosis, in order to suppress cancer. This Analysis article provides an overview of the current knowledge of p53-regulated genes in these pathways and others, and the mechanisms of their regulation. In addition, we present the most comprehensive list so far of human p53-regulated genes and their experimentally validated, functional binding sites that confer p53 regulation. IS - 5 JF - Nature reviews. Molecular cell biology SN - 1471-0080 EP - 412 TI - Transcriptional control of human p53-regulated genes. PB - Nature Publishing Group VL - 9 SP - 402 KW - p53 KW - review AU - Riley, Todd AU - Sontag, Eduardo AU - Chen, Patricia AU - Levine, Arnold PY - 2008/05// UR - http://dx.doi.org/10.1038/nrm2395 ER -