Magnetic field dependence of proton spin-lattice relaxation times Export

@article{citeulike:3340336, abstract = {The magnetic field dependence of the water-proton spin-lattice relaxation rate (1/T1) in tissues results from magnetic coupling to the protons of the rotationally immobilized components of the tissue. As a consequence, the magnetic field dependence of the water-proton (1/T1) is a scaled report of the field dependence of the (1/T1) rate of the solid components of the tissue. The proton spin-lattice relaxation rate may be represented generally as a power law: 1/T1omega = Aomega-b, where b is usually found to be in the range of 0.5-0.8. We have shown that this power law may arise naturally from localized structural fluctuations along the backbone in biopolymers that modulate the proton dipole-dipole couplings. The protons in a protein form a spin communication network described by a fractal dimension that is less than the Euclidean dimension. The model proposed accounts quantitatively for the proton spin-lattice relaxation rates measured in immobilized protein systems at different water contents, and provides a fundamental basis for understanding the parametric dependence of proton spin-lattice relaxation rates in dynamically heterogeneous systems, such as tissues. Magn Reson Med 48:21-26, 2002. {\copyright} 2002 Wiley-Liss, Inc.}, address = {Laboratoire de Physique de la Mati\`{e}re Condens\'{e}e, UMR 7643 du CNRS, \'{E}cole Polytechnique, Palaiseau, France; Chemistry Department, University of Virginia, Charlottesville, Virginia}, author = {Korb, Jean-Pierre and Bryant, Robert G.}, citeulike-article-id = {3340336}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/mrm.10185}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/12111928}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=12111928}, citeulike-linkout-3 = {http://www3.interscience.wiley.com/cgi-bin/abstract/95016022/ABSTRACT}, doi = {10.1002/mrm.10185}, issn = {1522-2594}, journal = {Magnetic Resonance in Medicine}, keywords = {relaxometry}, month = {July}, number = {1}, pages = {21--26}, posted-at = {2009-07-26 09:36:51}, priority = {2}, title = {Magnetic field dependence of proton spin-lattice relaxation times}, url = {http://dx.doi.org/10.1002/mrm.10185}, volume = {48}, year = {2002} }

TY - JOUR ID - citeulike:3340336 L3 - citeulike-article-id:3340336 N2 - The magnetic field dependence of the water-proton spin-lattice relaxation rate (1/T1) in tissues results from magnetic coupling to the protons of the rotationally immobilized components of the tissue. As a consequence, the magnetic field dependence of the water-proton (1/T1) is a scaled report of the field dependence of the (1/T1) rate of the solid components of the tissue. The proton spin-lattice relaxation rate may be represented generally as a power law: 1/T1omega = Aomega-b, where b is usually found to be in the range of 0.5-0.8. We have shown that this power law may arise naturally from localized structural fluctuations along the backbone in biopolymers that modulate the proton dipole-dipole couplings. The protons in a protein form a spin communication network described by a fractal dimension that is less than the Euclidean dimension. The model proposed accounts quantitatively for the proton spin-lattice relaxation rates measured in immobilized protein systems at different water contents, and provides a fundamental basis for understanding the parametric dependence of proton spin-lattice relaxation rates in dynamically heterogeneous systems, such as tissues. Magn Reson Med 48:21-26, 2002. © 2002 Wiley-Liss, Inc. IS - 1 JF - Magnetic Resonance in Medicine SN - 1522-2594 AD - Laboratoire de Physique de la Matière Condensée, UMR 7643 du CNRS, École Polytechnique, Palaiseau, France; Chemistry Department, University of Virginia, Charlottesville, Virginia EP - 26 TI - Magnetic field dependence of proton spin-lattice relaxation times VL - 48 SP - 21 KW - relaxometry AU - Korb, Jean-Pierre AU - Bryant, Robert PY - 2002/07// UR - http://dx.doi.org/10.1002/mrm.10185 ER -