Physical activity in adolescence and young adulthood and breast cancer risk: a quantitative review. Export

@article{citeulike:3733841, abstract = {Physical activity habits are potentially modifiable and could therefore be targeted in a primary prevention strategy against breast cancer, provided there is causality and a sufficiently strong relationship. Our objective of this quantitative review was to provide a summary estimate of the association of moderate/vigorous recreational physical activity during adolescence/young adulthood with breast cancer risk, and to determine whether a dose-response relationship exists. Data sources included studies in humans relating physical activity to breast cancer risk, published between January 1966 and October 2002, identified on Medline, the Web of Science, from reference lists and related reviews. The main characteristics of each study, the point estimates of relative risk (RR) and confidence intervals (CI) were extracted from 19 case-control and four cohort studies. Comparing the highest to the lowest category of physical activity, the summary RR from the random effects model was 0.81 (95\% CI 0.73-0.89). This almost 20\% risk reduction proved to be fairly consistent, despite variation in populations and methods. Each one-hour increase of recreational physical activity/week during adolescence was associated with a 3\% (95\% CI 0-6\%) risk reduction. Physical activity in 12-24-year-old females significantly reduces risk of breast cancer. Heterogeneity may be explained by different methods to measure activity.}, author = {Lagerros, Y. T. and Hsieh, S. F. and Hsieh, C. C.}, citeulike-article-id = {3733841}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/15075782}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=15075782}, issn = {0959-8278}, journal = {European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)}, keywords = {activity, breast, cancer, physical, superlist, thelist}, month = {February}, number = {1}, pages = {5--12}, posted-at = {2008-12-02 01:47:55}, priority = {2}, title = {Physical activity in adolescence and young adulthood and breast cancer risk: a quantitative review.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/15075782}, volume = {13}, year = {2004} }

TY - JOUR ID - citeulike:3733841 L3 - citeulike-article-id:3733841 N2 - Physical activity habits are potentially modifiable and could therefore be targeted in a primary prevention strategy against breast cancer, provided there is causality and a sufficiently strong relationship. Our objective of this quantitative review was to provide a summary estimate of the association of moderate/vigorous recreational physical activity during adolescence/young adulthood with breast cancer risk, and to determine whether a dose-response relationship exists. Data sources included studies in humans relating physical activity to breast cancer risk, published between January 1966 and October 2002, identified on Medline, the Web of Science, from reference lists and related reviews. The main characteristics of each study, the point estimates of relative risk (RR) and confidence intervals (CI) were extracted from 19 case-control and four cohort studies. Comparing the highest to the lowest category of physical activity, the summary RR from the random effects model was 0.81 (95% CI 0.73-0.89). This almost 20% risk reduction proved to be fairly consistent, despite variation in populations and methods. Each one-hour increase of recreational physical activity/week during adolescence was associated with a 3% (95% CI 0-6%) risk reduction. Physical activity in 12-24-year-old females significantly reduces risk of breast cancer. Heterogeneity may be explained by different methods to measure activity. IS - 1 JF - European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) SN - 0959-8278 EP - 12 TI - Physical activity in adolescence and young adulthood and breast cancer risk: a quantitative review. VL - 13 SP - 5 KW - activity KW - breast KW - cancer KW - physical KW - superlist KW - thelist AU - Lagerros, YT AU - Hsieh, SF AU - Hsieh, CC PY - 2004/02// UR - http://view.ncbi.nlm.nih.gov/pubmed/15075782 ER -