Dietary Patterns and Breast Cancer Recurrence and Survival Among Women With Early-Stage Breast Cancer Export

@article{citeulike:3893031, abstract = {Purpose: To determine the association of dietary patterns with cancer recurrence and mortality of early-stage breast cancer survivors.Patients and Methods: Patients included 1,901 Life After Cancer Epidemiology Study participants diagnosed with early-stage breast cancer between 1997 and 2000 and recruited primarily from the Kaiser Permanente Northern California Cancer Registry. Diet was assessed at cohort entry using a food frequency questionnaire. Two dietary patterns were identified: prudent (high intakes of fruits, vegetables, whole grains, and poultry) and Western (high intakes of red and processed meats and refined grains). Two hundred sixty-eight breast cancer recurrences and 226 all-cause deaths (128 attributable to breast cancer) were ascertained. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95\% CIs.Results: Increasing adherence to a prudent dietary pattern was associated with a statistically significant decreasing risk of overall death (P trend = .02; HR for highest quartile = 0.57; 95\% CI, 0.36 to 0.90) and death from non-breast cancer causes (P trend = .003; HR for highest quartile = 0.35; 95\% CI, 0.17 to 0.73). In contrast, increasing consumption of a Western dietary pattern was related to an increasing risk of overall death (P trend = .05) and death from non-breast cancer causes (P = .02). Neither dietary pattern was associated with risk of breast cancer recurrence or death from breast cancer. These observations were generally not modified by physical activity, being overweight, or smoking.Conclusion: Women diagnosed with early-stage breast cancer might improve overall prognosis and survival by adopting more healthful dietary patterns. 10.1200/JCO.2008.19.4035}, author = {Kwan, Marilyn L. and Weltzien, Erin and Kushi, Lawrence H. and Castillo, Adrienne and Slattery, Martha L. and Caan, Bette J.}, citeulike-article-id = {3893031}, citeulike-linkout-0 = {http://dx.doi.org/10.1200/JCO.2008.19.4035}, citeulike-linkout-1 = {http://jco.ascopubs.org/cgi/content/abstract/27/6/919}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19114692}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19114692}, day = {29}, doi = {10.1200/JCO.2008.19.4035}, journal = {J Clin Oncol}, keywords = {breast, cancer, diet, early-stage, recurrence}, month = {December}, pages = {JCO.2008.19.4035+}, posted-at = {2009-10-08 07:07:58}, priority = {2}, title = {Dietary Patterns and Breast Cancer Recurrence and Survival Among Women With Early-Stage Breast Cancer}, url = {http://dx.doi.org/10.1200/JCO.2008.19.4035}, year = {2008} }

TY - JOUR ID - citeulike:3893031 L3 - citeulike-article-id:3893031 N2 - Purpose: To determine the association of dietary patterns with cancer recurrence and mortality of early-stage breast cancer survivors.Patients and Methods: Patients included 1,901 Life After Cancer Epidemiology Study participants diagnosed with early-stage breast cancer between 1997 and 2000 and recruited primarily from the Kaiser Permanente Northern California Cancer Registry. Diet was assessed at cohort entry using a food frequency questionnaire. Two dietary patterns were identified: prudent (high intakes of fruits, vegetables, whole grains, and poultry) and Western (high intakes of red and processed meats and refined grains). Two hundred sixty-eight breast cancer recurrences and 226 all-cause deaths (128 attributable to breast cancer) were ascertained. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% CIs.Results: Increasing adherence to a prudent dietary pattern was associated with a statistically significant decreasing risk of overall death (P trend = .02; HR for highest quartile = 0.57; 95% CI, 0.36 to 0.90) and death from non-breast cancer causes (P trend = .003; HR for highest quartile = 0.35; 95% CI, 0.17 to 0.73). In contrast, increasing consumption of a Western dietary pattern was related to an increasing risk of overall death (P trend = .05) and death from non-breast cancer causes (P = .02). Neither dietary pattern was associated with risk of breast cancer recurrence or death from breast cancer. These observations were generally not modified by physical activity, being overweight, or smoking.Conclusion: Women diagnosed with early-stage breast cancer might improve overall prognosis and survival by adopting more healthful dietary patterns. 10.1200/JCO.2008.19.4035 JF - J Clin Oncol TI - Dietary Patterns and Breast Cancer Recurrence and Survival Among Women With Early-Stage Breast Cancer SP - JCO.2008.19.4035 KW - breast KW - cancer KW - diet KW - early-stage KW - recurrence AU - Kwan, Marilyn AU - Weltzien, Erin AU - Kushi, Lawrence AU - Castillo, Adrienne AU - Slattery, Martha AU - Caan, Bette PY - 2008/12/29/ UR - http://dx.doi.org/10.1200/JCO.2008.19.4035 ER -