Adolescent diet and risk of breast cancer. Export

@article{citeulike:5243388, abstract = {OBJECTIVES: To investigate the components of adolescent diet that may influence risk of breast cancer as an adult. METHODS: Retrospective cohort study among 47,355 participants in the Nurses Health Study II who answered a 131-item food frequency questionnaire about diet during high school. Cox proportional hazards regression was used to estimate relative risks and 95\% confidence intervals among incident cases of breast cancer between 1989 (inception of the study) and 1998 (when high school diet was assessed). RESULTS: Intakes of fat and fiber were not significantly related to risk of breast cancer in multivariate analysis, but increased intake of vegetable fat ( Q (5) versus Q (1) multivariate RR = 0.58, 95\% CI (0.38-0.86); test for trend p = 0.005) and vitamin E ( Q (5) versus Q (1) multivariate RR = 0.61, 95\% CI (0.42-0.89); test for trend p = 0.003) were associated with a lower risk. A higher dietary glycemic index ( Q (5) versus Q (1) multivariate RR = 1.47, 95\% CI (1.04-2.08); test for trend p = 0.01) was associated with increased risk of breast cancer. CONCLUSIONS: The apparent protective effects of vegetable fat and vitamin E and adverse effect of high glycemic foods on risk of breast cancer need confirmation in prospective analyses.}, author = {Frazier, A. L. and Li, L. and Cho, E. and Willett, W. C. and Colditz, G. A.}, citeulike-article-id = {5243388}, citeulike-linkout-0 = {http://dx.doi.org/10.1023/B:CACO.0000016617.57120.df}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/14970737}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=14970737}, doi = {10.1023/B:CACO.0000016617.57120.df}, issn = {0957-5243}, journal = {Cancer causes \& control : CCC}, keywords = {breast, cancer, diet, height, superlist, thelist}, month = {February}, number = {1}, pages = {73--82}, posted-at = {2009-07-23 23:10:23}, priority = {2}, title = {Adolescent diet and risk of breast cancer.}, url = {http://dx.doi.org/10.1023/B:CACO.0000016617.57120.df}, volume = {15}, year = {2004} }

TY - JOUR ID - citeulike:5243388 L3 - citeulike-article-id:5243388 N2 - OBJECTIVES: To investigate the components of adolescent diet that may influence risk of breast cancer as an adult. METHODS: Retrospective cohort study among 47,355 participants in the Nurses Health Study II who answered a 131-item food frequency questionnaire about diet during high school. Cox proportional hazards regression was used to estimate relative risks and 95% confidence intervals among incident cases of breast cancer between 1989 (inception of the study) and 1998 (when high school diet was assessed). RESULTS: Intakes of fat and fiber were not significantly related to risk of breast cancer in multivariate analysis, but increased intake of vegetable fat ( Q (5) versus Q (1) multivariate RR = 0.58, 95% CI (0.38-0.86); test for trend p = 0.005) and vitamin E ( Q (5) versus Q (1) multivariate RR = 0.61, 95% CI (0.42-0.89); test for trend p = 0.003) were associated with a lower risk. A higher dietary glycemic index ( Q (5) versus Q (1) multivariate RR = 1.47, 95% CI (1.04-2.08); test for trend p = 0.01) was associated with increased risk of breast cancer. CONCLUSIONS: The apparent protective effects of vegetable fat and vitamin E and adverse effect of high glycemic foods on risk of breast cancer need confirmation in prospective analyses. IS - 1 JF - Cancer causes & control : CCC SN - 0957-5243 EP - 82 TI - Adolescent diet and risk of breast cancer. VL - 15 SP - 73 KW - breast KW - cancer KW - diet KW - height KW - superlist KW - thelist AU - Frazier, AL AU - Li, L AU - Cho, E AU - Willett, WC AU - Colditz, GA PY - 2004/02// UR - http://dx.doi.org/10.1023/B:CACO.0000016617.57120.df ER -